Early and transient reverse transcription during primary deltaretroviral infection of sheep [PDF]
Retrovirology, 2008 Background Intraindividual genetic variability plays a central role in deltaretrovirus replication and associated leukemogenesis in animals as in humans. To date, the replication of these viruses has only been investigated during the chronic phase of the
Wattel Eric +7 more
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Post-transcriptional Regulation of HTLV Gene Expression: Rex to the Rescue [PDF]
Frontiers in Microbiology, 2019 Human T-lymphotropic virus type 1 (HTLV-1) and other members of the Deltaretrovirus genus code for a regulatory protein named Rex that binds to the Rex-responsive element present on viral mRNAs.
Donna M. D’Agostino +4 more
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Cytokine secretion in stem cells of cattle infected with bovine leukaemia virus
Journal of Veterinary ResearchBovine leukaemia virus (BLV) is a Deltaretrovirus responsible for enzootic bovine leukosis, the most common neoplastic disease of cattle. It deregulates the immune system, favouring secondary infections and changes in the blood and lymphatic tissues ...
Szczotka Maria, Kuźmak Jacek
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A dose-effect relationship for deltaretrovirus-dependent leukemogenesis in sheep
Retrovirology, 2009 Background Retrovirus-induced tumors develop in a broad range of frequencies and after extremely variable periods of time, from only a few days to several decades, depending mainly on virus type.
Franck Mortreux +2 more
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No genetic evidence for involvement of Deltaretroviruses in adult patients with precursor and mature T-cell neoplasms [PDF]
Retrovirology, 2007 Background The Deltaretrovirus genus comprises viruses that infect humans (HTLV), various simian species (STLV) and cattle (BLV). HTLV-I is the main causative agent in adult T-cell leukemia in endemic areas and some of the simian T-cell lymphotropic ...
Hoelzer Dieter +4 more
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Recent Advances in BLV Research [PDF]
Viruses, 2015 Different animal models have been proposed to investigate the mechanisms of Human T-lymphotropic Virus (HTLV)-induced pathogenesis: rats, transgenic and NOD-SCID/γcnull (NOG) mice, rabbits, squirrel monkeys, baboons and macaques.
Pierre-Yves Barez +14 more
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Engineered soluble truncated envelope proteins block bovine leukemia virus infection [PDF]
Virus ResearchBovine leukemia virus (BLV), a member of the delta retrovirus family, is transmitted horizontally among cows. BLV causes enzootic bovine leukosis and has great economic impact on the cattle industry.
Nashon Wanjala +4 more
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Epidemiology and genetic diversity of bovine leukemia virus
Virology Journal, 2017 Bovine leukemia virus (BLV), an oncogenic member of the Deltaretrovirus genus, is closely related to human T-cell leukemia virus (HTLV-I and II). BLV infects cattle worldwide and causes important economic losses.
Meripet Polat +2 more
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Detection of Bovine Leukemia Virus in Bone Marrow of Patients with B-Cell Precursor Acute Lymphoblastic Leukemia: A Case–Control Study [PDF]
VirusesBovine leukemia virus (BLV) is an oncogenic deltaretrovirus that infects B cells, and its possible presence in humans has garnered increasing attention.
Kerlimber Núñez-Gutiérrez +4 more
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Prevalence of human T-cell lymphotropic virus in blood donor screening at the Blood Center: a descriptive study, Mato Grosso, 2018-2021 [PDF]
Epidemiologia e Serviços de SaúdeObjectives: To describe the prevalence of human T-lymphotropic virus types 1 and 2 (HTLV-1/2) infection among blood donors at the Mato Grosso Blood Center between January 2018 and August 2021, as well as to report the demographic characteristics and ...
Pennsylvania Marinho Borralho +7 more
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