Results 51 to 60 of about 1,441 (129)

Epidemiology and genetic diversity of bovine leukemia virus

Virology Journal, 2017
Bovine leukemia virus (BLV), an oncogenic member of the Deltaretrovirus genus, is closely related to human T-cell leukemia virus (HTLV-I and II). BLV infects cattle worldwide and causes important economic losses.
Meripet Polat, Shin-nosuke Takeshima, Yoko Aida   +2 more
doaj   +1 more source

Effects of Naturally Occurring Mutations in Bovine Leukemia Virus 5′-LTR and Tax Gene on Viral Transcriptional Activity

Pathogens, 2020
Bovine leukemia virus (BLV) is a deltaretrovirus infecting bovine B cells and causing enzootic bovine leucosis (EBL). The long terminal repeat (LTR) plays an indispensable role in viral gene expression. The BLV Tax protein acts as the main transactivator
Aneta Pluta, Luc Willems, Renée N. Douville, Jacek Kuźmak   +3 more
doaj   +1 more source

Bovine Leukemia Virus: Global Prevalence and Localized Resurgence in China Revealed by an Integrated Meta‐Analysis and Case Series

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Background Bovine leukemia virus (BLV), the causative agent of enzootic bovine leukosis (EBL), causes substantial economic losses in the global cattle industry. While some regions have made progress in terms of control, the global epidemiological landscape and situation in China have not been fully elucidated.
Ruicheng Yu, Sen Zhang, Zhijie Xiang, Liyun Wan, Marawan A. Marawan, Jianguo Chen, Aizhen Guo, Yingyu Chen, Fedor Korennoy   +8 more
wiley   +1 more source

Establishment and Characterization of Human Cell Lines Stably Infected With Bovine Leukemia Virus In Vitro Reveals Apoptosis After Latency and Silencing

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Bovine leukemia virus (BLV) is the etiological agent of B‐cell leukemia/lymphoma in cattle worldwide. Although previous studies have linked BLV to breast cancer in women, its zoonotic potential remains controversial. Moreover, no previous studies have clearly investigated the BLV latency in human cells.
Samy Metwally, Rania Hamada, Ryosuke Matsuura, Yoko Aida, Efstathios Giotis S   +4 more
wiley   +1 more source

HIGHLIGHTS ON DISTINCTIVE STRUCTURAL AND FUNCTIONAL PROPERTIES OF HTLV TAX PROTEINS.

Frontiers in Microbiology, 2013
Human T-cell Leukemia Viruses (HTLVs) are complex human retroviruses of the Deltaretrovirus genus. Four types have been identified thus far, with HTLV-1 and HTLV-2 much more prevalent than HTLV-3 or -4 .
Maria Grazia Romanelli, Erica eDiani, Elisa eBergamo, Claudio eCasoli, Vincenzo eCiminale, Françoise eBex, Umberto eBertazzoni   +6 more
doaj   +1 more source

Bovine Leukemia Virus DNA in Human Breast Tissue

Emerging Infectious Diseases, 2014
Bovine leukemia virus (BLV), a deltaretrovirus, causes B-cell leukemia/lymphoma in cattle and is prevalent in herds globally. A previous finding of antibodies against BLV in humans led us to examine the possibility of human infection with BLV. We focused
Gertrude Case Buehring, Hua Min Shen, Hanne M. Jensen, K. Yeon Choi, Dejun Sun, Gerard Nuovo   +5 more
doaj   +1 more source

Reduced levels of reactive oxygen species correlate with inhibition of apoptosis, rise in thioredoxin expression and increased bovine leukemia virus proviral loads

Retrovirology, 2009
Background Bovine Leukemia virus (BLV) is a deltaretrovirus that induces lymphoproliferation and leukemia in ruminants. In ex vivo cultures of B lymphocytes isolated from BLV-infected sheep show that spontaneous apoptosis is reduced.
François Carole, Florins Arnaud, Boxus Mathieu, Bouzar Amel, Reichert Michal, Willems Luc   +5 more
doaj   +1 more source

Circulating Cell‐Free DNA of Bovine Leukemia Virus: A Promising Biomarker for Enzootic Bovine Leukosis

Microbiology and Immunology, Volume 69, Issue 9, Page 466-476, September 2025.
ABSTRACT Bovine leukemia virus (BLV) causes Enzootic bovine leukosis (EBL) in approximately 1%–5% of infected cattle after a long latent period. Few biomarkers effectively distinguish non‐EBL from EBL cattle. Given the rapid turnover of tumor cells, we hypothesized that cell‐free DNA (cfDNA) in plasma could serve as a more effective biomarker for EBL ...
M. Ishrat Jahan, Toshiaki Inenaga, Sakurako Makimoto, Md. Belal Hossain, Yuka Matsuoka, Sharmin Nahar Sithi, Samiul Alam Rajib, Arif Nur Muhammad Ansori, Kenji Sugata, Kazuhiko Imakawa, Tomoko Kobayashi, Yorifumi Satou   +11 more
wiley   +1 more source

Computational analysis of envelope glycoproteins from diverse geographical isolates of bovine leukemia virus identifies highly conserved peptide motifs

Retrovirology, 2018
Background Bovine leukemia virus (BLV) is a deltaretrovirus infecting bovine B cells and causing enzootic bovine leucosis. The SU or surface subunit, gp51, of its envelope glycoprotein is involved in receptor recognition and virion attachment.
Aneta Pluta, Lorraine M. Albritton, Marzena Rola-Łuszczak, Jacek Kuźmak   +3 more
doaj   +1 more source

Bovine leukemia virus tax gene/Tax protein polymorphism and its relation to Enzootic Bovine Leukosis

Virulence, 2020
Bovine leukemia virus (BLV) is an oncogenic retrovirus of the Deltaretrovirus genus, which causes persistent infection in its natural hosts – cattle, zebu, and water buffalo with diverse clinical manifestations through the defeat of B-cells.
Irina M. Zyrianova, Svetlana N. Kovalchuk   +1 more
doaj   +1 more source