Results 11 to 20 of about 1,726 (150)

Remnants of an Ancient Deltaretrovirus in the Genomes of Horseshoe Bats (Rhinolophidae) [PDF]

open access: yesViruses, 2018
Endogenous retrovirus (ERV) sequences provide a rich source of information about the long-term interactions between retroviruses and their hosts. However, most ERVs are derived from a subset of retrovirus groups, while ERVs derived from certain other ...
Helena Fábryová   +2 more
exaly   +8 more sources

North American Big Brown Bats (Eptesicus fuscus) Harbor an Exogenous Deltaretrovirus

open access: yesmSphere, 2020
Bats are the reservoir for a large number of zoonotic viruses, including members of Coronaviridae (severe acute respiratory syndrome coronavirus [SARS-CoV] and SARS-CoV-2), Paramyxoviridae (Hendra and Nipah viruses), Rhabdoviridae (rabies virus), and ...
Ben M. Hause   +2 more
doaj   +4 more sources

Unique Structure and Distinctive Properties of the Ancient and Ubiquitous Gamma-Type Envelope Glycoprotein

open access: yesViruses, 2023
After the onset of the AIDS pandemic, HIV-1 (genus Lentivirus) became the predominant model for studying retrovirus Env glycoproteins and their role in entry.
Welkin E Johnson
exaly   +4 more sources

A Dose-Effect Relationship for Deltaretrovirus-Dependent Leukemogenesis in Sheep [PDF]

open access: yesRetrovirology, 2009
Background Retrovirus-induced tumors develop in a broad range of frequencies and after extremely variable periods of time, from only a few days to several decades, depending mainly on virus type.
Franck Mortreux   +2 more
exaly   +7 more sources

Vitamins as Modulators of Deltaretrovirus Infection: Implications for HTLV-1 and Bovine Leukemia Virus-Associated Diseases [PDF]

open access: yesArchives of Microbiology
Deltaretroviruses, particularly human T-cell leukemia virus type 1 (HTLV-1) and bovine leukemia virus (BLV), are oncogenic retroviruses responsible for severe lymphoproliferative and inflammatory diseases, including adult T-cell leukemia/lymphoma (ATLL) and HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP). Despite decades of research,
Mohammad Mehdi Akbarin   +1 more
exaly   +4 more sources

Deltaretroviruses have circulated since at least the Paleogene and infected a broad range of mammalian species [PDF]

open access: yesRetrovirology, 2019
The Deltaretrovirus genus of retroviruses (family Retroviridae) includes the human T cell leukemia viruses and bovine leukemia virus (BLV). Relatively little is known about the biology and evolution of these viruses, because only a few species have been ...
Tomáš Hron   +2 more
doaj   +2 more sources

Detection of Bovine Leukemia Virus in Argentine, Bolivian, Paraguayan and Cuban Native Cattle Using a Quantitative Real-Time PCR Assay-BLV-CoCoMo-qPCR-2 [PDF]

open access: yesPathogens
Bovine leukemia virus (BLV), an oncogenic retrovirus of the genus Deltaretrovirus, causes enzootic bovine leukosis (EBL), the most prevalent neoplastic disease in cattle and a major source of economic loss.
Guillermo Giovambattista   +9 more
doaj   +2 more sources

Virus de la leucemia bovina: entre la producción animal y la salud humana

open access: yesRevista Mvz Cordoba, 2023
El virus de la leucemia bovina (BLV) es un retrovirus del género deltaretrovirus, el cual infecta los linfocitos B y genera una expansión policlonal. En los rumiantes se integra como provirus al genoma del huésped y genera una infección de por vida.
Daniela Paternina B   +2 more
doaj   +2 more sources

Structural basis for the inhibition of HTLV-1 integration inferred from cryo-EM deltaretroviral intasome structures [PDF]

open access: yesNature Communications, 2021
Human T-cell lymphotropic virus type 1 (HTLV-1) is an oncogenic deltaretrovirus. Here the authors provide structural characterization of the binding mechanism of novel integrase strand transfer inhibitor (INSTI) candidates to limit HTLV-1 infection.
Michal S. Barski   +10 more
doaj   +3 more sources

Molecular Studies of HTLV-1 Replication: An Update

open access: yesViruses, 2016
Human T-cell leukemia virus type 1 (HTLV-1) was the first human retrovirus discovered. Studies on HTLV-1 have been instrumental for our understanding of the molecular pathology of virus-induced cancers.
Joachim D. Mueller   +2 more
exaly   +3 more sources

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