Detection of Bovine Leukemia Virus in Bone Marrow of Patients with B-Cell Precursor Acute Lymphoblastic Leukemia: A Case–Control Study [PDF]
VirusesBovine leukemia virus (BLV) is an oncogenic deltaretrovirus that infects B cells, and its possible presence in humans has garnered increasing attention.
Kerlimber Núñez-Gutiérrez +4 more
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Post-transcriptional Regulation of HTLV Gene Expression: Rex to the Rescue [PDF]
Frontiers in Microbiology, 2019 Human T-lymphotropic virus type 1 (HTLV-1) and other members of the Deltaretrovirus genus code for a regulatory protein named Rex that binds to the Rex-responsive element present on viral mRNAs.
Donna M. D’Agostino +4 more
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Epidemiology and genetic diversity of bovine leukemia virus
Virology Journal, 2017 Bovine leukemia virus (BLV), an oncogenic member of the Deltaretrovirus genus, is closely related to human T-cell leukemia virus (HTLV-I and II). BLV infects cattle worldwide and causes important economic losses.
Meripet Polat +2 more
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Cytokine secretion in stem cells of cattle infected with bovine leukaemia virus
Journal of Veterinary ResearchBovine leukaemia virus (BLV) is a Deltaretrovirus responsible for enzootic bovine leukosis, the most common neoplastic disease of cattle. It deregulates the immune system, favouring secondary infections and changes in the blood and lymphatic tissues ...
Szczotka Maria, Kuźmak Jacek
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Recent Advances in BLV Research [PDF]
Viruses, 2015 Different animal models have been proposed to investigate the mechanisms of Human T-lymphotropic Virus (HTLV)-induced pathogenesis: rats, transgenic and NOD-SCID/γcnull (NOG) mice, rabbits, squirrel monkeys, baboons and macaques.
Pierre-Yves Barez +14 more
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Human T-Lymphotropic Viruses Evolution Possibly Explained by Primate Deltaretrovirus Geographical Segregation [PDF]
Retrovirology: Research and Treatment, 2008 The primate T cell lymphotropic virus group comprises pathogenic and apathogenic agents found in human and simian hosts. Up to date, three types of the simian T cell lymphotropic virus/STLV and four types of the human T cell lymphotropic virus/HTLV have been isolated and characterized from non human primates and from human hosts respectively.
Casseb, Jorge Simão do Rosário +1 more
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Reduced levels of reactive oxygen species correlate with inhibition of apoptosis, rise in thioredoxin expression and increased bovine leukemia virus proviral loads [PDF]
Retrovirology, 2009 Background Bovine Leukemia virus (BLV) is a deltaretrovirus that induces lymphoproliferation and leukemia in ruminants. In ex vivo cultures of B lymphocytes isolated from BLV-infected sheep show that spontaneous apoptosis is reduced.
François Carole +5 more
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Bovine Leukemia Virus DNA in Human Breast Tissue [PDF]
Emerging Infectious Diseases, 2014 Bovine leukemia virus (BLV), a deltaretrovirus, causes B-cell leukemia/lymphoma in cattle and is prevalent in herds globally. A previous finding of antibodies against BLV in humans led us to examine the possibility of human infection with BLV. We focused
Gertrude Case Buehring +5 more
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Stage-Dependent Transcriptional Reprogramming of B-Cell Receptor Signaling and Antigen Presentation During Bovine Leukemia Virus-Driven Lymphomagenesis. [PDF]
Anim GenetABSTRACT Bovine leukemia virus (BLV), an oncogenic deltaretrovirus, establishes lifelong infection in cattle and induces enzootic bovine leukosis in a subset of animals following prolonged latency. Despite extensive evidence of immune dysregulation, stage‐specific transcriptional reprogramming of B cells, the primary viral reservoir remains ...
Akbarin MM +6 more
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