Results 51 to 60 of about 118,970 (267)
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Distribution-Level Flexibility Market for Congestion Management
Energies, 2018 Nowadays, problems facing Distribution System Operators (DSOs) due to demand increase and the wide penetration of renewable energy are usually solved by means of grid reinforcement.
Ayman Esmat +2 more
doaj +1 more source
Energy Reports, 2022 Existing grids have been designed with traditional large centralized generation in mind; however, with the ever-increasing utilization of renewable distributed energy resources, the challenges of proper grid management have intensified.
Freddy Plaum +3 more
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Integration of circadian and hypoxia signaling via non‐canonical heterodimerization
FEBS Letters, EarlyView.CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley +1 more source
Appliance-Level Flexible Scheduling for Socio-Technical Smart Grid Optimization
IEEE Access, 2020 Participation in residential energy demand response programs requires an active role by consumers. They contribute flexibility in how they use their appliances as the means to adjust energy consumption, and reduce demand peaks, possibly at the expense of
Farzam Fanitabasi, Evangelos Pournaras
doaj +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Explanation of Flexibility Manufacturing Role in the World ClassCase study: Saipa automotive group [PDF]
پژوهشهای مدیریت عمومی, 2016 One of the major business risks in the world-class manufacturing and services firms is the risk of imbalance between supply and demand. To respond to fluctuations in demand, changing the capacity is an expensive strategy that some of organizations adopt ...
hasan Farsijani, ahmad Beklari
doaj +1 more source
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
EnergiesThe electrification of energy systems is essential for carbon reduction and sustainable energy goals. However, current network asset ratings and the poor thermal efficiency of older buildings pose significant challenges.
Thet Paing Tun +2 more
doaj +1 more source