Results 81 to 90 of about 2,563,822 (300)

Prospecting the protein design landscape

FEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona, Katharina T. Stonig, Jens Meiler, Clara T. Schoeder, Monica L. Fernández‐Quintero   +4 more
wiley   +1 more source

Modeling demand flexibility in electrified supply chains: optimizing manufacturing and transport under carbon pricing

Frontiers in Energy Research
IntroductionThis study presents a novel framework for leveraging temporal slack in end-to-end electrified logistics systems to enable medium- to long-duration load flexibility.MethodsWe formulate a coordinated optimization of energy-intensive ...
Changli Wu, Zhan Wang, Jinyue Li, Xiaohan Sun   +3 more
doaj   +1 more source

Optimal Scheduling of Integrated Energy Systems Considering Electric Vehicle Charging Patterns and Supply-Demand Flexibility [PDF]

Dianli jianshe
[Objective] To enhance the flexibility and low-carbon performance of integrated energy systems （IES）， this study proposes an optimal scheduling strategy that accounts for various electric vehicle （EV） charging modes and supply-demand flexibility ...
LIU Weimin, XIAO Hui, ZENG Linjun, YAN Qin, GUO Huidong, WU Yongxiao
doaj   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Electricity Demand Forecasting Based on Flexibility Characterization

Electricity
Electricity demand forecasting is essential for optimizing energy management and planning in microgrids and institutional contexts. The purpose of this article is to demonstrate how flexibility characterization can serve as a structural foundation for ...
Jesús Alexander Osorio-Lázaro, Ricardo Isaza-Ruget, Javier Alveiro Rosero García   +2 more
doaj   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source

Impact of Income on Price and Income Responses in the Differential Demand System [PDF]

An extension of the differential demand system model is developed that allows the demand system’s income and price responses to vary with income level.
Brown, Mark G.
core   +2 more sources

Is Being Flexible Advantageous for Demands?

IEEE Transactions on Power Systems, 2017
This paper analyzes the impacts of flexible demands on day-ahead market outcomes in a system with significant wind power production. We use a two-stage stochastic market-clearing model, where the first stage represents the day-ahead market and the second stage represents the real-time operation.
Abbaspourtorbati, Farzaneh, Conejo, Antonio J., Wang, Jianhui, Cherkaoui, Rachid   +3 more
openaire   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Smaller is better: nanobodies meet NMR

FEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source