Results 131 to 140 of about 27,738 (240)

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Automated water demand forecasting for national-scale deployment: a prophet-based framework for Palestinian municipal water management. [PDF]

Sci Rep
Salman A, Shaka'a Y.
europepmc   +1 more source

The application of specialised management assistants in demand forecasting of human resources. [PDF]

Heliyon, 2022
Wang S, Wang L, Liu D, Xin Y, Sun G, Wang Y, Wang J, Ping L.   +7 more
europepmc   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Demand forecasting and inventory optimization of distribution equipment: A fusion model based on genetic algorithm and machine learning. [PDF]

PLoS One
Tu Q, Zhang H, Li W, Duan J, Kong C.
europepmc   +1 more source

A robust autonomous method for blood demand forecasting. [PDF]

Transfusion, 2022
Turkulainen EV, Wemelsfelder ML, Janssen MP, Arvas M.   +3 more
europepmc   +1 more source

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

FEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz, Bruna Abreu, Cindy Mendes, Catarina Freitas‐Dias, Filipe Gonçalves, Fernanda Silva, José Ramalho, Saudade André, Vasco D. B. Bonifácio, Jacinta Serpa   +9 more
wiley   +1 more source

Age-sensitive urban rail passenger demand forecasting and uncertainty-driven anomaly detection using a hybrid SAINT + CatBoost ensemble. [PDF]

Sci Rep
Akçay MT.
europepmc   +1 more source

Interpretable tourism demand forecasting with temporal fusion transformers amid COVID-19. [PDF]

Appl Intell (Dordr), 2023
Wu B, Wang L, Zeng YR.
europepmc   +1 more source

Forecasting intermittent demand

, 2006
Methods for forecasting intermittent demand are compared using a large data-set from the UK Royal Air Force (RAF). Several important results are found. First, we show that the traditional per period forecast error measures are not appropriate for intermittent demand, even though they are consistently used in the literature.
Teunter, R H, Duncan, L
openaire   +1 more source