Results 101 to 110 of about 645,156 (309)
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
, 2008 The world summit on sustainable development in Johannesburg concluded that changing unsustainable patterns of energy use is a key area for global action to ensure survival of our planet.
Krumdieck, S., Gyamfi, S., Brackney, L.
core
Residents Demand Response Strategy Considering Rolling Evaluation
Zhongguo dianli, 2019 Carrying out demand response can effectively stabilize the load fluctuation and reduce the difference between peak and valley load power consumption.
Yi SUN +5 more
doaj +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Demand-Side Flexibility for Energy Transitions: Ensuring the Competitive Development of Demand Response Options [PDF]
This report provides an overview of the current debates about demand response development, focusing primarily on Europe, with some comparisons to the United States. ‘Demand response’ includes strategies that involve end-use customers adapting or altering
Nursimulu, Anjali +2 more
core +1 more source
Demand Response Design of Domestic Heat Pumps
Designs, 2017 This paper proposes an emergency-based demand response (DR) controller of domestic heat pump (DHP) units based on an estimated frequency of the UK electricity in 2035.
Mohammed Jasim M. Al Essa
doaj +1 more source
Forecast-Based Mechanisms for Demand Response
International Joint Conference on Autonomous Agents and Multiagent Systems, 2019 We study mechanisms to incentivize demand response in smart energy systems. We assume agents that can respond (reduce their demand) with some probability if they prepare prior to the realization of the demand. Both preparation and response incur costs to agents.
Methenitis, G. (author) +2 more
openaire +4 more sources
The human gut microbiome across the life course
FEBS Letters, EarlyView.Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
Evaluating Demand Response Programs: Getting the Key Performance Indicators Right [PDF]
, 2015 Demand Response (DR) has recently garnered great attention, with many DR programs being deployed and evaluated worldwide. They are hailed as a significant benefit enabled by the Smart Grid and an efficient method to engage consumers in managing their ...
Jain, Mohit +11 more
core
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source