Results 111 to 120 of about 645,156 (309)

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Simulative evaluation of demand response approaches for waterbeds

open access: yes, 2016
This paper quantitatively compares five demand response (DR) approaches for waterbeds using simulation. The approaches enable privacy by design with a local control and contribute to the planning phase of the electricity network's balancing process ...
Turau, Volker, Venzke, Marcus
core  

Optimization of Generation and Aggregated Consumption Shifting for Demand Response Programs Definition

open access: yes, 2014
The concept of demand response has drawing attention to the active participation in the economic operation of power systems, namely in the context of recent electricity markets and smart grid models and implementations.
Pedro Faria   +3 more
core   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

A demand response approach locally implementable for waterbeds

open access: yes, 2015
This paper presents a demand response scheme for waterbeds that can be implemented with currently available infrastructure. It balances the requirements of saving energy and shifting power to times with higher power availability by scheduling heating ...
Turau, Volker, Venzke, Marcus
core  

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

A blockchain consortium-based framework to enhance interoperability, standardization, and secure demand response management in smart grid applications

open access: yesResults in Engineering
The rapid advancement of smart grids, propelled by the integration of distributed energy resources (DERs) and renewable energy technologies, has exposed key challenges such as interoperability, standardization, and data security.
Arvind R. Singh   +4 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Unlocking Demand Response at the Building Level: a Distributed Energy Optimisation Approach

open access: yes, 2019
International audienceIn this paper, we propose a distributed optimisation approach based on Alternating Direction Method of Multipliers to optimise building energy consumption, reduce energy bills, and adopt demand response (DR) schemes at the building ...
Kem, Oudom, Ksontini, Feirouz
core  

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