Results 71 to 80 of about 1,206,124 (263)

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

The electric commons: A qualitative study of community accountability [PDF]

, 2017
This study explores how energy might be conceptualised as a commons, a resource owned and managed by a community with a system of rules for production and consumption.
Araral, Bauwens, Beckel, Blanchet, Bollier, Bowen, Buchanan, Burchell, Burchell, Burchell, Butler, Catney, Celia Way, Cox, Cox, DECC, Döbelt, Ehrhardt-Martinez, Emilia Melville, Frischmann, Frontier Economics, Sustainability First, Gardner, Harries, Horne, Hyde, Ian Christie, Jamieson, Kate Burningham, Kloza, Levitas, Moreno-Munoz, Morse, Naus, Ostrom, Phil Hampshire, Rose, Skjølsvold, Solove, Solove, Solove, Stadler, Sweeney, Thumim, VaasaETT, Weisburd, Wilson, Yadoo   +46 more
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Self-optimization method of resident demand response strategy based on priority queue

电力工程技术, 2022
Resident load is one of the important components of seasonal peak load and has huge demand response (DR) potential. But its randomness and decentralization limit the ability to flexibly participate in DR interactions.
LI Yang, YAN Qiang, FAN Youjie, SHI Yunpeng   +3 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Demand Response Readiness in Retail Stores: DR Control Preferences, Stakeholder Engagement, and Cross-National Differences

, 2018
Retail buildings can provide energy flexibility to the grid with the possibility of load shifting and building automation systems. Demand response is a collective innovation in the smart grid domain. Various stakeholders should be involved in the demand response activities to ensure the success.
Zheng Ma, Kati Kuusinen, Mikkel Baun Kjærgaard, Bo Nørregaard Jørgensen   +3 more
openaire   +2 more sources

Simplified Algorithm for Dynamic Demand Response in Smart Homes Under Smart Grid Environment

, 2019
Under Smart Grid environment, the consumers may respond to incentive--based smart energy tariffs for a particular consumption pattern. Demand Response (DR) is a portfolio of signaling schemes from the utility to the consumers for load shifting/shedding ...
Namboodiri, Aryesh, Selvan, M. P., Singh, Shashank   +2 more
core   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Prediksi Safety Stock Produk Filter Oli Sepeda Motor Berbasis Demand Response (DR) - ARMA

bit-Tech
Manajemen rantai pasokan merupakan hal krusial yang dibutuhkan dalam menjaga persediaan suatu produk supaya tetap tersedia selama masa tunggu. Hal ini bertujuan untuk menjaga keberlanjutan suatu bisnis sehingga penjualan produk tersebut tidak terganggu dengan permasalahan kurangnya persediaan. Namun, metode prediksi konvensional seperti ARMA-klasik dan
Sandi Tendean, Jimmy Tjen, Riyadi Jimmy Iskandar   +2 more
openaire   +1 more source

The role of demand response in mitigating market power - A quantitative analysis using a stochastic market equilibrium model. ESRI WP635, August 2019 [PDF]

, 2019
Market power is a dominant feature of many modern electricity markets with an oligopolistic structure, resulting in increased consumer cost. This work investigates how consumers, through demand response (DR), can mitigate against market power. Within DR,
Bertsch, Valentin, Devine, Mel T.
core