Results 61 to 70 of about 4,443 (260)

Data-Driven Modeling of Demand-Responsive Transit: Evaluating Sustainability Across Urban, Rural, and Intercity Scenarios

Systems
Demand-responsive transit (DRT) is an innovative public transportation model that dynamically adjusts routes based on passengers’ specific demands. While existing studies offer insights into routing, scheduling, and network design, they remain fragmented,
Yunxi Zhang, Linjie Gao, Xu Zhao, Anning Ni   +3 more
doaj   +1 more source

Data-driven assessment for the predictability of demand responsive transit

Transportmetrica A: Transport Science
By adapting bus routes to users' requests, Demand-Responsive Transit (DRT) can serve low-demand areas more efficiently than conventional fixed-line buses. However, a main barrier to its adoption of DRT is its unpredictability, i.e., it is not possible to know a-priori how much time a certain trip will take, especially when no large prebooking is ...
Leonardi, Pierfrancesco, Torrisi, Vincenza, Araldo, Andrea, Ignaccolo, Matteo   +3 more
openaire   +2 more sources

Demand-responsive transit systems in areas with low transport demand of “smart city”

Transportation Research Procedia, 2020
Abstract The development of modern telecommunications allows the concept of a “smart city” to increase the flexibility of public transportation significantly and, thus, improve population mobility. In this regard, public transportation represents a demand-responsive transit (DRT) system.
Andrey Gorev, Olga Popova, Aleksandr Solodkij   +2 more
openaire   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Optimal Design of Demand-Responsive Feeder Transit Services with Passengers’ Multiple Time Windows and Satisfaction

Future Internet, 2018
This paper presents a mixed-integer linear programming model for demand-responsive feeder transit services to assign vehicles located at different depots to pick up passengers at the demand points and transport them to the rail station.
Bo Sun, Ming Wei, Senlai Zhu
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

An Assessment of Microtransit Impacts on its Substitution and Complementarity with other Modes

Findings
In March of 2022, the Metropolitan Atlanta Rapid Transit Authority, or MARTA, which had previously been a fixed-route system only, implemented a demand-responsive transit system called MARTA Reach.
Maha Ahmad, Lillian Cella, Susan C. Pike, Bailey Affolter, Kari E. Watkins   +4 more
doaj   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

RNA‐related functions of BRCA2 in transcription, replication, and genome stability

FEBS Letters, EarlyView.
Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda, Sreerama Chaitanya Sridhara, Aura Carreira   +2 more
wiley   +1 more source

Older people and local public transit: Mobility effects of accessibility improvements in Sweden

Journal of Transport and Land Use, 2009
Several transportation factors concerning older and disabled people are under transition in Sweden at present. By the year 2010, the public transit system must be fully accessible for all passengers.
Anders Wretstrand, Helena Svensson, Sofi Fristedt, Torbjörn Falkmer   +3 more
doaj   +1 more source