Results 41 to 50 of about 4,443 (260)

Classical Complement Pathway Inhibition in a Pediatric Patient With Refractory Immune Thrombocytopenia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric refractory immune thrombocytopenia (rITP) is generally characterized by persistent thrombocytopenia and failure to achieve a sustained response to multiple standard therapies. We report a 4‐year‐old female with congenital tufting enteropathy, post‐intestinal transplant patient on immunosuppressants, who developed severe rITP ...
Sarah Hsieh, Susmita Sarangi, Caileigh Pudela, Catherine M. Broome, Tara K. Suntum   +4 more
wiley   +1 more source

Dynamic Scheduling of Electric Demand Responsive Transit Considering Time-of-Use Pricing

Journal of Advanced Transportation
Demand-responsive transit (DRT) has been widely adopted in many cities worldwide due to its advantages of flexible routing and personalized services.
Jiadong Wang, Zhenzhou Yuan, Zhenying Yan, Meiying Jian, Feng Hao   +4 more
doaj   +1 more source

Novel model for integrated demand-responsive transit service considering rail transit schedule

Mathematical Biosciences and Engineering, 2022
<abstract> <p>This research aims to develop an optimization model for optimizing demand-responsive transit (DRT) services. These services can not only direct passengers to reach their nearest bus stops but also transport them to connecting stops on major transit systems at selected bus stops.
Yingjia Tan, Bo Sun, Li Guo, Binbin Jing
openaire   +3 more sources

Evidence‐Based Clinical Practice Guidelines for the Management of Pediatric Febrile Neutropenia: Resource‐Sensitive Recommendations for the Asian Continent

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Febrile neutropenia (FN) is a frequent and serious complication in children receiving cancer therapy. Standardizing FN management across Asia is challenging due to variable healthcare infrastructure, diagnostic capacity, and infection patterns; however, it could improve resource use and patient outcomes.
Joliza Patricia Cañeba, Shweta Bansal, Tea Reljic, Allyne Montecillo‐Aguelo, Hamidah Alias, Farrah Amaranto, Maria Stella Aquino‐Calingasan, Bambang Ardianto, Eggi Arguni, Sally Blair, Thi Tam Dang, Maria Beatriz Gepte, Samanmalee Gunasekara, Andini Handayani, Miriam Kimpo, Catherine G. Lam, Nawachai Lertvivatpong, Sergio Licona, Ana Loseo, Ratha Mlis, Vivian Moreno Berrio, Nguyen Hoai Anh, Anna Lisa Ong‐Lim, Ha Thu Pham, Krishna Sagar Sharma, Bun Sereyleak, Sally Jane G. Velasco‐Aro, Su Yadana, Ambuj Kumar, Sheena Mukkada   +29 more
wiley   +1 more source

Flex-Route Transit for Smart Cities: A Reinforcement Learning Approach to Balance Ridership and Performance

Smart Cities
A major challenge for modern transit systems relying on traditional fixed-route designs is providing broad accessibility to users. Flex-route transit can enhance accessibility in low-density areas, since it combines the directness of fixed-route transit ...
Joseph Rodriguez, Haris N. Koutsopoulos, Jinhua Zhao   +2 more
doaj   +1 more source

Performance analysis and fleet requirements of automated demand-responsive transport systems as an urban public transport service

International Journal of Transportation Science and Technology, 2018
The introduction of public transport services by fully automated vehicles can potentially change the way public transit services will be operated, as they allow shifting from rigid scheduled and route-bound services towards flexible, demand-responsive ...
Konstanze Winter, Oded Cats, Gonçalo Correia, Bart van Arem   +3 more
doaj   +1 more source

Iterated clustering optimization of the split-delivery vehicle routing problem considering passenger walking distance

Transportation Research Interdisciplinary Perspectives, 2023
The user-oriented, demand-driven nature of customized shuttle bus (CSB) services forces operators to pay more attention to service quality. However, the bus route planning of CSB and other similar systems in established studies rarely took service ...
Jiangbo Wang, Zhirui Lian, Chao Liu, Kai Liu   +3 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Feeding Urban Rail Transit: Hybrid Microtransit Network Design Based on Parsimonious Continuum Approach

Information
In recent years, the passenger flow volume of conventional transit in major cities has declined steadily. Ground public transit often suffers from congestion during rush hours caused by frequent stops (e.g., conventional fixed-route buses) or excessively
Qian Ye, Yunyu Zhang, Kunzheng Wang, Xinghua Liu, Chunfu Shao   +4 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source