Results 111 to 120 of about 37,908 (265)
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To evaluate the expression of nine blood RNA biomarkers in a clinical trial based on genes previously identified in an experimental monkey model of stroke for diagnosis feasibility and prognostication. Methods IBIS‐CT1 was a prospective longitudinal study enrolling patients with ischemic stroke (IS) or intracerebral hemorrhage (ICH ...
Salomé Retailleau +11 more
wiley +1 more source
A cost-effective strategy for enhancing mobility in aging communities: the case of Narita City
Frontiers in SustainabilityIn depopulated areas with aging populations, it is challenging to design public transportation services. This is because municipalities are expected to provide mobility to as many people as possible within a limited budget while considering the various ...
Takuto Ojima +2 more
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To investigate which baseline clinical and imaging characteristics best predict TSPO‐PET‐measurable reduction in glial activation following treatment of multiple sclerosis (MS), to utilize this information for designing more efficient biomarker‐based clinical trials targeting glial activation.
Marlene T. Morch +5 more
wiley +1 more source
Transportation Research Interdisciplinary PerspectivesDemand-responsive transport (DRT) is expected to be a transport mode that solves first- and last-mile mobility problems. This study aimed to investigate the potential association of multimodal transport (buses or railways) with DRT on daily walking steps.
Haruka Kato
doaj +1 more source
Natural Frequencies of Levodopa‐Induced Dyskinesia in Parkinson's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objectives Abnormal involuntary movements, known as dyskinesias, are common complications of levodopa treatment in patients with Parkinson's disease and can significantly impair quality of life. The underlying pathophysiology remains unclear, and current therapeutic options are limited.
Ioannis U. Isaias +3 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Treatment of disorders of consciousness (DoC) remains a major clinical challenge, and noninvasive, targeted modulation of deep brain structures has emerged as a promising therapeutic strategy. We aimed to evaluate the feasibility/safety and preliminary effects of thalamic temporal interference stimulation (TIS) targeting centromedian‐
Gengyao Hu +7 more
wiley +1 more source
Integration of freight transportation in demand responsive transport systems
, 2020 Demand-Responsive Transport (DRT) describes public transport modes, which do not run on a fixed schedule but the customers can order their trip including time windows, origin and destinations themselves. Especially for rural areas with lower demand for passengers, DRT systems seem to be suitable concepts.
openaire +1 more source
Progressive Parkinsonism in PPP2R5D‐Related Neurodevelopmental Disorder
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT PPP2R5D‐related neurodevelopmental disorder (Houge–Janssens syndrome type 1) is a rare autosomal dominant condition characterized by macrocephaly, intellectual disability, and epilepsy. Progressive parkinsonism is an emerging adult phenotype that neurologists should be aware of since timely genetic diagnosis opens the door to disease‐modifying
Katerina Bernardi +6 more
wiley +1 more source
FindingsDemand-responsive transport (DRT) systems struggle to strike a balance between universal accessibility and efficient, equitable service delivery. This study utilises MATSim to evaluate two distinct DRT policies in Greater Melbourne: a serve-all policy ...
Sapan Tiwari
doaj +1 more source