Results 81 to 90 of about 39,009 (301)

Evaluation of demand responsive transport schemes

open access: yes, 2004
Report prepared for Department for Transport/Greater Manchester/Passenger Transport ...
Parkhurst, Graham   +3 more
core  

Content and Evaluation of an Enterprise Reference Architecture for Demand-Responsive Public Transport

open access: yes, 2023
Demand-responsive public transport, such as new mobility solutions (NMS) like car sharing, city bikes, call taxis or e-scooters, have become increasingly popular in big cities. NMS have started to influence how people move around in urban areas, and they
Würtz, M. -O,, Sandkuhl, Kurt,
core   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

Recent Advances in Demand Responsive Transport: Opportunities With Autonomous Bus Service—A System-of-Systems Overview

open access: yesIEEE Access
This study explores recent advancements in emerging technologies for Demand Responsive Transport (DRT), focusing on the potential integration of autonomous bus services.
Sajid Fadlelseed   +10 more
doaj   +1 more source

A survey of research on demand responsive transit and its route optimization

open access: yes智能科学与技术学报, 2021
With the widespread application of new infrastructure and other technologies, demand responsive transit (DRT) is becoming the trend of urban traffic development in the future.In order to further clarify the research status of DRT at home and abroad ...
Shuai FENG, Xiaoming LIU
doaj  

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

User-Centered Development of a Public Transportation Vehicle Operated in a Demand Responsive Environment [PDF]

open access: yes, 2019
Within the scope of the research project "Reallabor Schorndorf", funded by the German state, demand responsive transport and operating systems as well as a virtual vehicle concept for public transport (PT) were designed and tested in a "real-world ...
Gerhard Kopp   +7 more
core   +1 more source

ESR1 methylation and ESR1 mutations in circulating tumor cells (CTCs) and paired plasma‐cfDNA of advanced breast cancer patients: A feasibility proof‐of‐concept study

open access: yesMolecular Oncology, EarlyView.
Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou   +12 more
wiley   +1 more source

Methodology for Determining the Territories Where Scheduled Public Transport Should Be Changed to DRT

open access: yesFuture Transportation
To address the evolving mobility requirements of local (suburban) and regional public transportation systems, it is imperative to employ service models capable of adapting to low-density and variable demand.
Rasa Ušpalytė-Vitkūnienė   +2 more
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

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