Results 71 to 80 of about 234,133 (352)
3D Chromatin Architecture Provides Insights Into Leaf Trait Variation Among Pear Species
Advanced Science, EarlyView.ABSTRACT Three‐dimensional (3D) chromatin architecture plays a fundamental role in eukaryotic gene regulations, its functional significance in perennial fruit trees remains poorly characterized despite extensive applications in crop genomics. Here, we developed high‐resolution (∼5 kb) Hi‐C maps of Pyrus and compared 3D genomic architecture of three ...
Yueyuan Liu +11 more
wiley +1 more source
Karl Popper’s demarcation problem [PDF]
Karl Popper, as a critical rationalist, was an opponent of all forms of skepticism, conventionalism and relativism in science. A major argument of Popper is Hume's critique of induction, arguing that induction should never be used in science.
Sfetcu, Nicolae
core
The rhetoric of failure: a hyper-dialog about method in economics and how to get things going [PDF]
, 2012 All are agreed that orthodox economics is unsatisfactory but there is wide disagreement, especially among heterodox critics, whether the problems lie at the level of substantive theory or at the level of methodology. This paper gives first an overview of
Kakarot-Handtke, Egmont
core +1 more source
Advanced Science, EarlyView.ABSTRACT Liver metastasis is a leading cause of mortality in colorectal cancer (CRC), where the inflammatory tumor microenvironment, specifically neutrophil infiltration, significantly promotes metastatic colonization. This study reveals a pro‐metastatic role for alpha‐1 antitrypsin (A1AT) in CRC liver metastasis via a dual mechanism involving ...
Qian Fei +11 more
wiley +1 more source
Phase Diagrams and Piezoelectric Properties of Wurtzite Al1−x−yScxGdyN Heterostructural Alloys
Advanced Science, EarlyView.This study demonstrates ferroelectricity and piezoelectric properties improvement of quaternary wurtzite Al1−x−yScxGdyN${\rm Al}_{1-x-y}{\rm Sc}_x{\rm Gd}_y{\rm N}$ films, guided by density functional theory calculations. Wurtzite Al1−x−yScxGdyN${\rm Al}_{1-x-y}{\rm Sc}_x{\rm Gd}_y{\rm N}$ films have a high optical bandgap, enhanced piezoelectric ...
Julia L. Martin +11 more
wiley +1 more source
PhilosophiesEvidence-based medicine (EBM) supplies the best available data, yet clinicians still face low-value care, surrogate-driven reversals, and pseudoscientific claims. We propose Semi-Imperative Evidentialism (SIE), a normative framework that links evidential
José Nunes de Alencar +2 more
doaj +1 more source
Why We Can't Have Our Facts Back
Engaging Science, Technology, and Society, 2018 How do we make the case for “knowledge democracy” in the face of the growing influence of right-wing figures and movements that denounce experts and expertise?
Noortje Marres
doaj +1 more source
Shot peening for Ti-6Al-4V alloy compressor blades [PDF]
A text program was conducted to determine the effects of certain shot-peening parameters on the fatigue life of the Ti-6Al-4V alloys as well as the effect of a demarcation line on a test specimen.
Carek, Gerald A.
core +1 more source
Advanced Science, EarlyView.HNRNPD promotes radioresistance in nasopharyngeal carcinoma by enhancing stress granule assembly and sequestering GRAMD4 mRNA. This suppresses GRAMD4 translation and inhibits mitochondrial apoptosis. Targeting the integrated stress response with ISRIB restores GRAMD4 expression and sensitizes tumors to radiotherapy, revealing a translational control ...
Yingzi Li +13 more
wiley +1 more source
The role of coordinates in border diplomacy: The case of Albania [PDF]
Micro, Macro & Mezzo GeoinformationThis study addresses the essential importance of geodetic coordinates in border diplomacy, focusing on the case of Albania. State borders represent not only geographical divisions, but also sovereignty, national identity, and economic interest.
Anduel Cauli, Pal Nikolli, Oltion Pupi
doaj +1 more source