Results 171 to 180 of about 1,119,525 (359)
Advanced Healthcare Materials, EarlyView.Cerebral organoids are transforming brain research, yet the field remains fragmented. This comprehensive systematic review maps 738 studies published between 2014 and 2024 to uncover trends, gaps, and opportunities across neuroscience. Introducing OrganoidMap—an interactive, open‐access platform to explore and compare models—this work enables ...
Anna Wolfram +10 more
wiley +1 more source
COGNITIVE/CLINICAL ENDPOINTS FOR PRE-DEMENTIA AD TRIALS [PDF]
, 2015 Paul Aisen
openalex +1 more source
Advanced Materials, EarlyView.This study reports the fabrication of MRI‐compatible elastomeric micro‐balloons via a multi‐step bubble casting process, where the monolithic elastomeric wall is selectively stiffened for reversible and controlled inflation and elasticity, depending on the target vessels for graded occlusion of cerebral arteries.
Jong Bin Kim +10 more
wiley +1 more source
Neuid: A Novel Neuron‐Enriched LncRNA that Connects Epigenetic Gene Silencing to Alzheimer's Disease
Advanced Science, EarlyView.ABSTRACT The increasing evidence that non‐coding RNAs can become deregulated during pathogenesis is dramatically expanding the space for drug discovery beyond the protein‐coding genome. Long noncoding RNAs (lncRNAs) are emerging as key regulators of cellular function, yet most remain uncharacterized.
Ranjit Pradhan +17 more
wiley +1 more source
Multimodal analysis of synchronization data from patients with dementia [PDF]
, 2017 Little is known about the abilities of people with dementia to synchronize bodily movements to music. The lack of non-intrusive tools that do not hinder patients, and the absence of appropriate analysis methods may explain why such investigations remain ...
Desmet, FrankUGent001960895315801000562960971854648585F4230C92-F0ED-11E1-A9DE-61C894A0A6B4 +5 more
core +1 more source
Cognitive Trajectories from Preclinical Alzheimer's Disease to Dementia
Advanced Science, EarlyView.A continuous, multi‐domain characterization of cognitive decline across the Alzheimer's disease spectrum identifies when individual cognitive measures become abnormal. Episodic memory declines first, followed by executive function, language, processing speed, and visuospatial abilities, supporting improved clinical interpretation and optimized endpoint
Fredrik Öhman +3 more
wiley +1 more source
Rapidly progressive dementia as a form of presentation of Cushing syndrome
, 2018 Claudia Rodríguez-López +2 more
openalex +1 more source
ASSOCIATION BETWEEN RENAL FUNCTION AND COGNITIVE PERFORMANCE IN ELDERLY COMMUNITY‐DWELLING MEN WITHOUT DEMENTIA [PDF]
, 2010 Albert C. Yang +6 more
openalex +1 more source
Advanced Science, EarlyView.This study tests NeuroD1 AAV‐based gene therapy in a non‐human primate Alzheimer's disease model. The therapy prevents neuronal damage, inhibits hippocampal atrophy, and reduces neuroinflammation. It also repairs vascular and blood‐brain barrier damage, restores cerebrospinal fluid biomarkers, enhances hippocampal glucose metabolism, and improves ...
Zhouquan Jiang +21 more
wiley +1 more source