Results 151 to 160 of about 717,640 (312)

Healthbridge: The National Evaluation of Peer Support Networks and Dementia Advisers in implementation of the National Dementia Strategy for England [PDF]

, 2013
This report, commissioned by the Department of Health, provides evidence on the importance of post diagnostic support for people with dementia and their carers, and the role that dementia advisers and peer support networks can provide in this ...
Hodgson, Philip, Cattan, Mima, Robinson, Louise, Alexjuk, Jo, Wilcockson, Jane, Keyes, Sarah, Reynolds, Joanna, Wilkinson, Heather, McClelland, Siobhan, Corner, Lynne, Clarke, Charlotte   +10 more
core  

An evaluation of an online postgraduate Dementia Studies program

, 2012
Education is key to addressing the challenges of providing high-quality care to the ever growing number of people with dementia. Although dementia education is required for multiple professions and disciplines working with people with dementia and their ...
Innes, Anthea, McCabe, Louise, Kelly, Fiona   +2 more
core   +1 more source

Impact of Apolipoprotein E4 on blood-brain barrier integrity in target replacement murine models: a systematic review and meta-analysis

Alzheimer’s Research & Therapy
Background The E4 variant of Apolipoprotein E (APOE) is a primary genetic susceptibility risk factor for late-onset Alzheimer’s disease and has been implicated in cerebrovascular dysfunction.
Krystal K. Laing, Nela Fialova, Joanna Wardlaw, Axel Montagne   +3 more
doaj   +1 more source

Early Retinal UCHL1 Dysregulation Coupled With Synaptic Loss Reflects Alzheimer's Disease Severity

Advanced Science, EarlyView.
This study identifies synapse‐enriched deubiquitinase UCHL1 as an early Aβ‐responsive regulator of retinal synaptopathy in Alzheimer's disease. Retinal UCHL1 loss accompanies excitatory synapse degeneration, p75NTR activation, and neuroinflammation, and predicts Braak stage and cognitive decline. Aβ42 fibrils trigger synaptic and UCHL1 depletion before
Altan Rentsendorj, Jean‐Philippe Vit, Alexandre Hutton, Yosef Koronyo, Saba Shahin, Edward Robinson, Ernesto Barron, Anthony Rodriguez, Ousman Jallow, Julia Sheyn, Bhakta Prasad Gaire, Lalita Subedi, Miyah R. Davis, Barathan Gnanabharathi, Alexander V. Ljubimov, Stuart L. Graham, Vivek K. Gupta, Mehdi Mirzaei, Debra Hawes, Katlin Silm, Keith L. Black, Lon S. Schneider, Alfredo A. Sadun, Jesse G. Meyer, Dieu‐Trang Fuchs, Maya Koronyo‐Hamaoui   +25 more
wiley   +1 more source

Architecture for dementia. Stirling Gold: 2008-2020

, 2021
‘Architecture for dementia’ is a compendium of international architecture projects each awarded the world renowned DSDC building accreditation ‘Gold’ award for dementia design.

core  

People Living With Dementia and Their Families as Educators for Social Justice

Health Expectations
Background It is increasingly recognised that dementia education and training should include the direct voices of Experts by Experience (people living with dementia and their families).
Clare Mason, Ana Barbosa, Danielle Jones, Michael Andrews, Andrea Capstick   +4 more
doaj   +1 more source

Alzheimer's Disease Beyond Amyloid: Lessons From Atherosclerosis

Annals of Clinical and Translational Neurology, EarlyView.
Marcello Ciaccio, Luisa Agnello
wiley   +1 more source

Molecular and Cellular Hallmarks of Age‐Related Vestibular Hair Cell Degeneration

Advanced Science, EarlyView.
This study utilizes single‐cell RNA‐seq transcriptomes, advanced imaging, and electrophysiology to examine universal and cell‐type‐specific aging signatures of vestibular hair cells. The study shows that impaired hair bundle function is a key driver of age‐related vestibular dysfunction.
Samadhi Kulasooriya, Huizhan Liu, Sarath Vijayakumar, Celia Bloom, Zhenhang Xu, Shu Tu, Benjamin J. Borgmeier, Mi Zhou, Litao Tao, Bechara Kachar, David Z. He   +10 more
wiley   +1 more source

Still Alice is far from a good thing for dementia awareness [PDF]

, 2015
First paragraph: Still Alice tells the story of a university professor who is diagnosed with an aggressive early-onset dementia. Her intellectual and physical capacity declines cruelly, and it’s certain that she has passed the genetic mutation
Andrews, June
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Harnessing Large‐Scale Multi‐Omics Data for Risk Prediction and Deep Phenotyping of Valvular Heart Diseases in the General Population

Advanced Science, EarlyView.
Large‐scale UK Biobank analyses identify clinical and proteomic signatures for early prediction of valvular heart disease and its subtypes. Proteins add predictive value for VHD, AVS, and MVR, with outcome‐specific compact panels showing translational potential. Multi‐layer evidence highlights matrix remodeling, protease regulation, immune inflammation,
Zhihao Jiang, Yang Liu, Mingyu Song, Ning Chen, Canqing Yu, Jun Lv, Eric Yuk Fai Wan, Lu Qi, Liming Li, Dianjianyi Sun, Bang Zheng   +10 more
wiley   +1 more source