Results 131 to 140 of about 717,640 (312)

Endothelial Cell Proteins as Biomarkers in Susac Syndrome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Susac syndrome (SS) is a rare CD8+ T cell–mediated microangiopathy affecting the brain, retina, and auditory labyrinth. Endothelial injury is thought to be a central mechanism; however, no circulating disease biomarkers are known. We performed targeted proteomic profiling to identify circulating endothelial‐associated proteins as ...
Rohit Benjamin, Yue Andy Qi, Ying Hao, Catherine DeMarino, Samuel Darko, Irene Cortese, Daniel S. Reich, María I. Gaitán, Steven Jacobson, Bridgett J. Billioux, Bryan Smith, Avindra Nath   +11 more
wiley   +1 more source

A comparison of modifiable risk factors for dementia among South Asian migrants and non-migrants aged 50 or older in Tasmania, Australia

BMC Public Health
Background South Asian migrants are one of the fastest-growing populations in Australia, particularly in the southern island state of Tasmania. However, there is limited research evaluating their modifiable dementia risk factors. This study aimed to fill
Mohammed Shoaib Hamrah, Jane Alty, Lynette R. Goldberg, Kathleen Doherty, Alex Kitsos, Aidan Bindoff, Eddy Roccati, Hiroshi Yatsuya, James Clement Vickers   +8 more
doaj   +1 more source

Data‐Driven SuStaIn Model of Disability Progression in Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine whether ordinal Subtype and Stage Inference (SuStaIn) applied to routine ALSFRS‐R item scores can identify reproducible disability progression patterns in amyotrophic lateral sclerosis (ALS) and provide clinically meaningful staging.
Giammarco Milella, Veria Vacchiano, Vittorio Velucci, Stefano Zoccolella, Rocco Liguori, Giovanni Defazio   +5 more
wiley   +1 more source

The Lupus Damage Index Revision Program: Results From the Item Generation and Reduction Phases

Arthritis Care &Research, EarlyView.
Objective A data‐driven and expert/patient consensus‐based project to develop a revised Systemic Lupus International Collaborating Clinics (SLICC)/American College of Rheumatology (ACR) Damage Index (SDI) is under way supported by SLICC, ACR, and the Lupus Foundation of America. Our objective is to report the item generation and reduction phase results
Burak Kundakci, Megan R. W. Barber, Ann E. Clarke, Sindhu R. Johnson, Anselm Mak, Hermine I. Brunner, Murat Inanc, Rosalind Ramsey‐Goldman, Guillermo Ruiz‐Irastorza, Ellen M. Ginzler, John G. Hanly, Alexandra Legge, Cynthia Aranow, Laurent Arnaud, Nathalie Costedoat‐Chalumeau, Dafna D. Gladman, Søren Jacobsen, Michelle Petri, Clovis A. Silva, Évelyne Vinet, Alexandre E. Voskuyl, SDI Revision Literature Review Groups, SDI Revision Delphi Panel, SDI Revision Item Reduction Committee, SDI Revision Clinical Domain Groups, Ian N. Bruce   +25 more
wiley   +1 more source

The Continuum of Care for People Living with Dementia in Ireland

, 2019
This review addresses one of the actions outlined in the National Dementia Strategy (2014) that the Health Service Executive will examine a range of appropriate long-term care options to accommodate the diverse needs of people living with dementia.
Cooney, Adeline, O'Shea, Eamon, Keogh, Fiona   +2 more
core  

Management of Cognitive Communication Difficulties in Dementia: A Cross Sectional Survey of Speech and Language Therapists

, 2020
Background: Cognitive communication difficulties are a characteristic feature of dementia. Speech and language therapists (SLTs) have an important role in managing cognitive communication difficulties associated with ...
Walshe, Margaret
core  

Post-Diagnostic Support for People with Dementia and their Carers [PDF]

, 2018
Review of the literature on dementia post-diagnostic ...
Heneghan, Ciara, O'Shea, Eamon, Keogh, Fiona   +2 more
core   +1 more source

Individuals With Multijoint Osteoarthritis Demonstrate Larger Longitudinal Declines in Frailty: Data From the Canadian Longitudinal Study on Aging

Arthritis Care &Research, EarlyView.
Objective The aim of this study was to test the hypothesis that multijoint osteoarthritis would modify the relation between time and frailty progression, in which more affected joints would lead to larger declines over six years compared to those without osteoarthritis using data from the Canadian Longitudinal Study on Aging.
Carson Halliwell, Rebecca Moyer, Myles W. O'Brien   +2 more
wiley   +1 more source

Engineered Nanotopography to Modulate Growth and Signaling of Neuronal Networks

Advanced Functional Materials, EarlyView.
This study examines the interaction between neurons and nanoscale topographies on engineered substrates. Neurons cultured on nanowires, nanopillars and nanoneedles exhibit enhanced neurite outgrowth, form more organized neuronal circuits, and display improved synaptic connectivity, compared to flat substrates.
Hao Nguyen Tran, Kalyan Shobhana, Zlatan Trifunovic, Dan Smith, Michael Stuiber, Chennupati Jagadish, Mirella Dottori, Andrea J. O'Connor, Vini Gautam   +8 more
wiley   +1 more source

Making Hampshire a dementia- friendly county. Finding out what a dementia friendly community means to people with dementia and carers

, 2012
Praktisk veilederThis is a guide for people working with people with dementia and their carers. In particular it is for those who want to support people with dementia and their carers to have a say in building a more dementia-friendly Hampshire.
Local Government Association, Hampshire County Counsil, Innovations in Dementia   +2 more
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