Results 181 to 190 of about 1,330,157 (395)
Advanced Science, EarlyView.Higher serum UA levels are associated with reduced AD risk in epidemiological studies. UA enhances microglial phagocytic capacity primarily by restoring CD36 and TREM2 receptor recycling that is impaired by Aβ exposure. Therapeutically, UA supplementation improves cognitive function and reduces neuropathology in AD mouse model by enhancing microglial ...
De Xie +18 more
wiley +1 more source
A CASE OF DEMENTIA DUE TO HUNTINGDON'S CHOREA. [PDF]
, 1905 G. Ernest Peachell
openalex +1 more source
Advanced Science, EarlyView.A high‐resolution intravital imaging platform combining functional ultrasound and localization microscopy enables longitudinal, minimally invasive assessment of cerebrovascular function in aging studies. The present investigation reveals aging‐related reductions in neurovascular coupling, arteriole‐to‐venule ratio and vascular density, introducing a ...
Sharon Negri +16 more
wiley +1 more source
Congenital Lues Causing Optic Atrophy and Ultimately Leading to Dementia Paralytica Juvenilis [PDF]
, 1910 Henry Head
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MRI Epicenters Differentiate Spatiotemporal Patterns of Neurodegeneration in Parkinson's Disease
Advanced Science, EarlyView.A connectivity‐based MRI epicenter model identifies two Parkinson's disease subtypes: subtype 1 with infratentorial‐dominant epicenters, severe motor symptoms, and rapid progression; and subtype 2 with supratentorial‐dominant epicenters with mild progression.
Xiaojie Duanmu +23 more
wiley +1 more source
PARTIAL THYROIDECTOMY FOR CATATONIC DEMENTIA PRÆCOX [PDF]
, 1910 Allen B. Kanavel, Lewis J. Pollock
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PIEZO Force Sensing in Vascular Biology: An Explosion of New Knowledge, Concepts and Opportunity
Advanced Science, EarlyView.Knowledge of the remarkable mechanical force sensing and electrically transducing PIEZO1 and PIEZO2 channels is discussed across vascular biology and its cell types from the embryonic to adult stages in health, disease and old age. How the channels work, relate to other factors and signal for tissue responses to mechanical forces is debated.
David J Beech
wiley +1 more source
The Ulster medical journal, 2015 Dementia is a clinical diagnosis requiring new functional dependence on the basis of progressive cognitive decline. It is estimated that 1.3% of the entire UK population, or 7.1% of those aged 65 or over, have dementia. Applying these to 2013 population estimates gives an estimated number of 19,765 people living with dementia in Northern Ireland.
Cunningham, E L +3 more
openaire +2 more sources
Dose–Response Associations of Grip Strength and Gait Speed With Multidimensional Mental Health
AGING MEDICINE, EarlyView.We found linear positive associations of grip strength and gait speed with most dimensions of mental health. The finding unveils the intrinsic connections between musculoskeletal function and mental health, highlighting the significance of preserving musculoskeletal function to prevent mental health disorders, especially for females and older adults ...
Jiapei Wei +8 more
wiley +1 more source