Results 281 to 290 of about 1,356,534 (397)

Extrapyramidal Signs by Dementia Severity in Alzheimer Disease and Dementia With Lewy Bodies

, 2012
Berneet Kaur, Danielle Harvey, Charles DeCarli, Lin Zhang, Marwan N. Sabbagh, John Olichney   +5 more
openalex   +1 more source

Spotlight commentary: Addressing the persistent problem of benzodiazepine overuse, time for clinical, educational and AI‐driven reform

British Journal of Clinical Pharmacology, EarlyView.
Jakša Vukojević, Luka Horvat, Vito Papić, Andrija Štajduhar   +3 more
wiley   +1 more source

Intracellular Catalytic Photooxygenation of α‐Synuclein Amyloid

ChemistryEurope, EarlyView.
Amyloid‐selective catalytic photooxygenation reduces amyloid toxicity, aggregation tendencies, and seeding activities. Achieving therapeutic catalysis for intracellular amyloids is challenging due to conflicting oxygenation and reductive cellular environments.
Atsushi Iwai, Youhi Hwang, Hiroki Umeda, Taka Sawazaki, Ikumi Tomizawa, Maiko Ono, Makoto Higuchi, Youhei Sohma, Yukiko Hori, Taisuke Tomita, Harunobu Mitsunuma, Motomu Kanai   +11 more
wiley   +1 more source

Kidney Function, Alzheimer Disease Blood Biomarkers, and Dementia Risk in Community-Dwelling Older Adults. [PDF]

Neurology
Gasparini F, Valletta M, Vetrano DL, Beridze G, Rizzuto D, Calderón-Larrañaga A, Fredolini C, Dale M, Winblad B, Fratiglioni L, Grande G.   +10 more
europepmc   +1 more source

Development of New Benzo[b]Thiophene‐2‐Carboxamide Derivatives as Advanced Glycation End‐Products Receptor (RAGE) Antagonists

ChemMedChem, EarlyView.
A streamlined Ullmann‐Goldberg strategy enabled the synthesis of benzo[b]thiophene‐2‐carboxamides, promising ligands of the pro‐inflammatory RAGE receptor involved in inflammaging and age‐related diseases. LC‐MS, NMR, X‐ray and DFT studies elucidated the copper‐catalyzed mechanism. The lead compound, 3t’, shows inhibitory activity on the sRAGE/AGE2‐BSA
Lisa Bonin, Matthieu Hedouin, Christophe Furman, Ophélie Not, Steve Lancel, Mona Bensalah, Gael Coadou, Eric Boulanger, Sergiu Shova, Hassan Oulyadi, Alina Ghinet   +10 more
wiley   +1 more source

Dementia in older adults with schizophrenia: a 12-year analysis of prevalence, incidence, and treatment patterns in South Korea. [PDF]

Schizophrenia (Heidelb)
Park JS, Kim S, Jeong D, Choi JP, Jeong H, Park AJ, Kim YS, Lee J, Kim SH.   +8 more
europepmc   +1 more source

From Brain Health to Brain Economy

Brain Health, EarlyView.
Yongjun Wang
wiley   +1 more source

Association Discovery Approach in Healthcare Big Data to Identify Drug Safety and Drug Repurposing Signals

Clinical Pharmacology &Therapeutics, EarlyView.
Data science approaches have been increasingly implemented in healthcare big data to evaluate the safety and effectiveness of drugs. Association discovery is a data mining approach that finds potentially associated elements in high‐dimensional data. We present a novel implementation of the association discovery approach in longitudinal healthcare data ...
George S. Q. Tan, Lynn Miller, Sam Wade, Jenni Ilomäki, Dickson Lukose, Jia Rong, Geoffrey I. Webb   +6 more
wiley   +1 more source

Radiomics models identifying dementia in patients with normal age-related hippocampal atrophy: a study based on machine learning. [PDF]

BMC Geriatr
Yang XL, Luo YF, Huang SW, Li C, Wang YY, Huang HH, Wang MX, Lu WM, Zong PP, Zeng HL, Wu DH.   +10 more
europepmc   +1 more source

α-Synuclein in filamentous inclusions of Lewy bodies from Parkinson’s disease and dementia with Lewy bodies

, 1998
M. Spillantini, R., Anthony Crowther, R. Jakes, M. Hasegawa, M. Goedert   +5 more
semanticscholar   +1 more source