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More Democracy Is Not Better Democracy: Cain's Case for Reform Pluralism [PDF]
, 2014 This article is part of a symposium on Bruce Cain's "Democracy More or Less: America’s Political Reform Quandary." It identifies the basic normative framework of Cain's skeptical "reform pluralism" as a form of democratic instrumentalism rather
Turner, Piers Norris
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FEBS Open Bio, EarlyView.Here, we introduced an intermittent electrical stimulation protocol mimicking the episodic nature of real‐life exercise in vitro by alternating low‐ and high‐frequency stimulation. In comparison with widely used continuous stimulation, it enhanced the rate of glucose and fatty acid oxidation, but not the myokine release.
Klára Gabrišová +11 more
wiley +1 more source
The Mysterious Travel of Drugs from Nature to Pharmacy
Forbes Tıp DergisiFor thousands of years, people have used various substances found in nature to relieve symptoms and even cure diseases. Drugs are medicinal products obtained from natural sources such as plants, animals, and microorganisms or synthesized in the ...
Gülden DİNİZ +5 more
doaj +1 more source
FEBS Open Bio, EarlyView.CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee +3 more
wiley +1 more source
E-democracy and values in information systems design [PDF]
, 2012 In this paper I demonstrate the utility of a Values in Design (VID) perspective for the assessment, the design and development of e-democracy tools. In the first part, I give some background information on Values in Design and Value-Sensitive Design and ...
Simon, Judith
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Thrombolytic proteins profiling: High‐throughput activity, selectivity, and resistance assays
FEBS Open Bio, EarlyView.We present optimized biochemical protocols for evaluating thrombolytic proteins, enabling rapid and robust screening of enzymatic activity, inhibition resistance, and fibrin affinity, stimulation, and selectivity. The outcome translates to key clinical indicators such as biological half‐life and bleeding risk. These assays streamline the development of
Martin Toul +3 more
wiley +1 more source
FEBS Open Bio, EarlyView.Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid +3 more
wiley +1 more source
e-Kafkas Eğitim Araştırmaları Dergisi: This research has been conducted to examine the relationship between teacher-child relationships school adjustment and social competence variables.
Aysel Adıgüzel, Sibel Yoleri
doaj +1 more source
Alternatives to Liberal Constitutional Democracy [PDF]
, 2017 The global appeal of liberal constitutional democracy—defined as a competitive multiparty system combined with governance within constitutional limits—cannot be taken for granted due to the existence of competing forms of government that appear ...
Law, David S.
core +1 more source
Democracy: History of a Crisis Without End [PDF]
, 2016 Over the last years it has been increasingly discussed about the crisis of democracy, a process that does not only concern the new realities, but also and perhaps more surprisingly the Western world.
CILENTO, Marco, Claudio, FOLITI, CLAUDIO
core +1 more source