Results 51 to 60 of about 1,463,862 (342)

How to measure multidimensional quality of life of persons with disabilities in public policies - a case of Poland

open access: yesArchives of Public Health, 2022
Background The aim of this paper is to construct a tool that can be used to measure multidimensional quality of life of persons with disabilities in comparison with population without disabilities for the purpose of monitoring of the UN Convention on the
Izabela Grabowska   +3 more
doaj   +1 more source

Network topology drives population temporal variability in experimental habitat networks

open access: yesPopulation Ecology, EarlyView.
Habitat patches connected by dispersal pathways form habitat networks. We explored how network topology affects population outcomes in laboratory experiments using a model species (Daphnia carinata). Central habitat nodes in complex lattice networks exhibited lower temporal variability in population sizes, suggesting they support more stable ...
Yiwen Xu   +3 more
wiley   +1 more source

Individual quality of life and the environment – towards a concept of livable areas for persons with disabilities in Poland

open access: yesBMC Public Health, 2021
Background The United Nations Convention on the Rights of Persons with Disabilities [1] highlights the need to create proper socioeconomic and political conditions for persons with disabilities, with a special focus on their immediate living conditions ...
Izabela Grabowska   +3 more
doaj   +1 more source

Circulating tumor cells in metastatic breast cancer patients treated with immune checkpoint inhibitors – a biomarker analysis of the ALICE and ICON trials

open access: yesMolecular Oncology, EarlyView.
In this explorative biomarker analysis, we assessed serial sampling of circulating tumor cells (CTCs) with CellSearch in two randomized trials testing immune checkpoint inhibitors (ICIs) in metastatic breast cancer. Our data demonstrate a prognostic potential of CTCs, most apparent 4 weeks into ICI therapy.
Nikolai Kragøe Andresen   +13 more
wiley   +1 more source

Demography and Archaeology

open access: yesHuman Biology, 2009
In the field of archaeology, demography has sometimes seemed something of a phantom science. Many explanatory models in archaeology have taken population density as a central theme. But the quantitative precision and broad sweep of the resulting formulations, scientific enough in their intentions, have often been undermined by the difficulties in the ...
openaire   +4 more sources

Plasma lipidomic and metabolomic profiles in high‐grade glioma patients before and after 72‐h presurgery water‐only fasting

open access: yesMolecular Oncology, EarlyView.
Presurgery 72‐h fasting in GB patients leads to adaptations of plasma lipids and polar metabolites. Fasting reduces lysophosphatidylcholines and increases free fatty acids, shifts triglycerides toward long‐chain TGs and increases branched‐chain amino acids, alpha aminobutyric acid, and uric acid.
Iris Divé   +7 more
wiley   +1 more source

The initial journey of an Endangered penguin: implications for seabird conservation

open access: yesEndangered Species Research, 2013
Seabirds can disperse widely in search of prey, especially during non-breeding periods. Conservation measures predominately focus on protecting breeding colonies, but juvenile survival and recruitment can have critical impacts on population dynamics.
RB Sherley   +5 more
doaj   +1 more source

On Secular Stagnation and Low Interest Rates: Demography Matters

open access: yesInternational Finance, 2017
Nominal and real interest rates in advanced economies have been decreasing since the mid-1980s and reached historical low levels in the aftermath of the global financial crisis.
G. Ferrero, M. Gross, S. Neri
semanticscholar   +1 more source

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

open access: yesMolecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

The atypical KRASQ22K mutation directs TGF‐β response towards partial epithelial‐to‐mesenchymal transition in patient‐derived colorectal cancer tumoroids

open access: yesMolecular Oncology, EarlyView.
TGF‐β has a complex role in cancer, exhibiting both tumor‐suppressive and tumor‐promoting properties. Using a series of differentiated tumoroids, derived from different stages and mutational background of colorectal cancer patients, we replicate this duality of TGF‐β in vitro. Notably, the atypical but highly aggressive KRASQ22K mutation rendered early‐
Theresia Mair   +17 more
wiley   +1 more source

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