Results 81 to 90 of about 1,704,046 (402)
Molecular Oncology, EarlyView.Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley +1 more source
Businesses, 2023 Research on the career expectations of employees and the potential (mis)match with their lived reality is abundant, yet the research field has paid less attention to the expectation–reality gap of the self-employed.
Jessie Gevaert +3 more
doaj +1 more source
Demography-based adaptive network model reproduces the spatial organization of human linguistic groups [PDF]
Phys. Rev. E 92, 062811 (2015), 2015 The distribution of human linguistic groups presents a number of interesting and non-trivial patterns. The distributions of the number of speakers per language and the area each group covers follow log-normal distributions, while population and area fulfill an allometric relationship.
arxiv +1 more source
Introduction to the Demography Volume [PDF]
, 1992 [Excerpt] This volume represents another effort by Research in the Sociology of Organizations to focus on a crucial issue in organizational sociology. In some of the previous volumes, we concentrated on organizations and professions (Volume 8, 1991), the
Bacharach, Samuel B, Tolbert, Pamela S
core +1 more source
Molecular Oncology, EarlyView.TGF‐β has a complex role in cancer, exhibiting both tumor‐suppressive and tumor‐promoting properties. Using a series of differentiated tumoroids, derived from different stages and mutational background of colorectal cancer patients, we replicate this duality of TGF‐β in vitro. Notably, the atypical but highly aggressive KRASQ22K mutation rendered early‐
Theresia Mair +17 more
wiley +1 more source
Predicting evolutionary rescue via evolving plasticity in stochastic environments [PDF]
Proc. R. Soc. B 283:20161690 (2016), 2016 Phenotypic plasticity and its evolution may help evolutionary rescue in a novel and stressful environment, especially if environmental novelty reveals cryptic genetic variation that enables the evolution of increased plasticity. However, the environmental stochasticity ubiquitous in natural systems may alter these predictions because high plasticity ...
arxiv +1 more source
Germline variants in CDKN2A wild‐type melanoma prone families
Molecular Oncology, EarlyView.Among melanoma‐prone families, wild‐type for CDKN2A and CDK4, some have pathogenic variants in genes not usually linked to melanoma. Furthermore, rare XP‐related variants and variants in MC1R are enriched in such families. Germline pathogenic variants in CDKN2A are well established as an underlying cause of familial malignant melanoma. While pathogenic
Gjertrud T. Iversen +5 more
wiley +1 more source
On the Demography of Aging [PDF]
Demography, 1980 This paper is concerned with the contributions of demography to gerontology or the demography of aging. The major interests of gerontological demographers and outstanding issues and problems are discussed in terms of the process of aging. Problems of definition of old age and aging are noted in terms of: 1) the lack of a universally acceptable ...
openaire +3 more sources
FEBS Open Bio, EarlyView.This study reports the upregulation of ELMO1 and GPR141 in human Fuchs' endothelial corneal dystrophy (FECD) corneal endothelium and ultraviolet A‐induced FECD mice model. A genetic association of an intergenic single nucleotide polymorphism rs918980 present between both genes is observed with FECD in the Indian population.
Susmita Sharma +3 more
wiley +1 more source