Results 31 to 40 of about 10,948 (258)
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Prilikom upotrebe minsko-eksplozivnih sredstava za rušenje elemenata, materijala i objekata jako je bitna organizacija izvođenja radova prilikom pripreme i u toku izvođenja samog rušenja.
Nenad V. Kovačević
doaj +1 more source
The old town house in Obrenovac [PDF]
The paper outlines the development of the commercial quarter of Obrenovac because it made possible the emergence of a formally elaborate town house in the style of Balkan architecture.
Živković Nada
doaj +1 more source
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Representações da violência no cinema de Pedro Costa
THE REPRESENTATIONS OF VIOLENCE IN THE CINEMA OF PEDRO COSTA This article aims to reflect about the violent reality represented by the Portuguese film director Pedro Costa in the Letters from Fontainhas trilogy.
Guilherme Figueiredo
doaj +1 more source
The disposal volume of material for Construction and Demolition in Europe is increasing each year, that the European Union has decided to take control of the matter unifying practices and goals to achieve. This article analyses how waste management works
Javier Cárcel-Carrasco +3 more
doaj +1 more source
PANoptosis in the pathogenesis of myelodysplastic syndromes
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová +2 more
wiley +1 more source
Towards urban LCA: examining densification alternatives for a residential neighbourhood
This paper explores the environmental impacts of retaining or replacing buildings by extending the consequential replacement framework (CRF) for life-cycle assessment (LCA) from individual buildings towards the urban scale. It addresses a gap in previous
Malin Moisio +7 more
doaj +1 more source
How phagocytic cells kill bacteria: Lessons from a professional killer
How phagocytic cells ingest and kill bacteria has been studied for more than a century, but many questions remain unanswered. The study of the amoeba Dictyostelium discoideum brings new answers, and new questions. Professional phagocytic cells such as neutrophils and macrophages, as well as free‐living soil amoebae like Dictyostelium discoideum, employ
Otmane Lamrabet, Pierre Cosson
wiley +1 more source

