Results 51 to 60 of about 194,353 (342)

AAA+ protein unfoldases—the Moirai of the proteome

open access: yesFEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

The Use of Demolition Wood in Papermaking [PDF]

open access: yes, 1996
The reason for this study came from three factors affecting the paper industry as well as society as a whole. These factors are decreasing landfill space, increasing tipping fees, and increasing demands for alternative fiber sources. In the United States,
Anderson, Todd W.
core   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Drivers of Housing Demolition Decision Making and the Impact on Timber Waste Management

open access: yesConstruction Economics and Building, 2011
The study investigates housing demolition and timber waste recovery – with the aim to identify ways of improving recovery. Using case studies the research focused on demolisher decision making, their onsite processes and the associated network of ...
Perry John Forsythe
doaj   +1 more source

Kralupy u Chomutova: Demolice obce kvůli rozšiřování těžby uhlí

open access: yesHistorická sociologie, 2020
The article is focused on the story of the village Kralupy u Chomutova, which was demolished in the 1970s due to the expanding coal mining. It monitors the process of demolition and response of its citizens.
Jana Vitíková
doaj   +1 more source

Comment on: "Measuring a Photonic Qubit without Destroying It" [PDF]

open access: yes, 2004
Recently, Pryde et al reported the demonstration of a quantum non-demolition scheme for single-photon polarization states with linear optics and projective measurements [Phys. Rev. Lett. 92, 190402 (2004)]. Here, we argue that their interpretation of the
Kok, Pieter, Munro, William J.
core   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Mihail Gorbaciov și Proiectul românesc de Sistematizare Rurală (1989) [PDF]

open access: yesPolis: Revista de Stiinte Politice, 2022
In 1989, the scandal broke out in the West because of the rural systematization project. The project involved the demolition of half of Romania’s villages, 7-8 thousand villages that were to be wiped off the face of the earth along with their cemeteries.
Nicoleta ȘERBAN
doaj  

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Home - About - Disclaimer - Privacy