Results 61 to 70 of about 181,853 (274)

Improvment of safety conditions of unstable rock slopes through the use of explosives [PDF]

, 2008
The paper discusses operations aimed at creating a safer natural or man made rock slope by artificially inducing the displacement of unstable elements by blasting.
Casale, M., Oggeri, Claudio, Peila, Daniele   +2 more
core   +3 more sources

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Towards urban LCA: examining densification alternatives for a residential neighbourhood

Buildings & Cities
This paper explores the environmental impacts of retaining or replacing buildings by extending the consequential replacement framework (CRF) for life-cycle assessment (LCA) from individual buildings towards the urban scale. It addresses a gap in previous
Malin Moisio, Emmi Salmio, Tapio Kaasalainen, Satu Huuhka, Aapo Räsänen, Jukka Lahdensivu, Minna Leppänen, Pirjo Kuula   +7 more
doaj   +1 more source

National Commission on Human Life Reproduction and Rhythm [PDF]

, 1969
A bulldozer continues to work on the demolition of Parks Hall as rubble surrounds the area.
Ratner, Herbert
core   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Recording Various Aspects of Unfair Practices of Parties During Legalization or Demolition of Unauthorized Structures

Вестник Кемеровского государственного университета. Серия: гуманитарные и общественные науки
Cases regarding the recognition of property rights to an unauthorized structure or its demolition often become the subject of judicial examination. These claims are often unjustifiable, which means unfair practice of one of the parties.
Vladislav A. Syrbo, Viktoriya A. Morozova   +1 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Antibiofilm activity of a chionodracine‐derived peptide by NMR‐based metabolomics of cell‐free supernatant of Acinetobacter baumannii clinical strains

FEBS Open Bio, EarlyView.
KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli, Enrico Landi, Francesco Maiurano, Irene Paris, Rosanna Papa, Marco Artini, Laura Selan, Stefano Borocci, Francesco Buonocore, Esther Imperlini   +9 more
wiley   +1 more source

A study on C&D waste generation and recycling potential in Gujarat [PDF]

ITM Web of Conferences
In the context of urbanization and construction’s unceasing expansion, management of Construction and Demolition (C&D) Waste is a major issue facing in the current era. About 30to 40% C&D waste is generate across globe.
Nair Sujithvelloor S.
doaj   +1 more source

Mihail Gorbaciov și Proiectul românesc de Sistematizare Rurală (1989) [PDF]

Polis: Revista de Stiinte Politice, 2022
In 1989, the scandal broke out in the West because of the rural systematization project. The project involved the demolition of half of Romania’s villages, 7-8 thousand villages that were to be wiped off the face of the earth along with their cemeteries.
Nicoleta ȘERBAN
doaj