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A number of viruses can initiate central nervous system (CNS) diseases that include demyelination as a major feature of neuropathology. In humans, the most prominent demyelinating diseases are progressive multifocal leukoencephalopathy, caused by JC papovirus destruction of oligodendrocytes, and subacute sclerosing panencephalitis, an invariably fatal ...
Fazakerley, JK, Walker, R
openaire +6 more sources
Inflammatory demyelinating polyneuropathy after total hip arthroplasty
Inflammatory demyelinating polyneuropathy is a rare but devastating condition. Guillain-Barré syndrome is the most common cause with acute inflammatory demyelinating polyneuropathy being the most common subtype that follows a monophasic course and does ...
Shane R. Hess, DO +3 more
doaj +2 more sources
Treatment of demyelinating disorders [PDF]
This invention discloses methods and compositions for the treatment of demyelinating disorders. Specifically, the invention relates to the use guanabenz or guanabenz derivative for treating demyelinating ...
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Objective: To investigate the effect of vanillic acid (VA) on a Cuprizone (Cup) demyelinating rat model and the mechanisms behind such effect. Methods: Thirty adult male Sprague Dawley (SD) rats were randomly divided into three groups: control, Cuprizone,
Sally M. Safwat +7 more
doaj +1 more source
Acute paretic syndrome in juvenile White Leghorn chickens resembles late stages of acute inflammatory demyelinating polyneuropathies in humans [PDF]
Background: Sudden limb paresis is a common problem in White Leghorn flocks, affecting about 1% of the chicken population before achievement of sexual maturity.
Sascha Trapp +26 more
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Occupational risk factors for multiple sclerosis: a systematic review with meta-analysis
ObjectiveWe decided to conduct the first systematic review with meta-analysis to provide the highest level of up-to-date evidence on the occupational risk factors for Multiple Sclerosis.MethodsA systematic, comprehensive literature search was performed ...
Bruno Kusznir Vitturi +7 more
doaj +1 more source
Recent advances in the diagnosis of immune mediated demyelinating neuropathies
Inflammatory neuropathies are a group of acquired neuropathies which could be due to autoimmune, infectious, paraneoplastic, or paraproteinemic etiology.
Shilpa Rao +2 more
doaj +1 more source
Glycoproteins as targets of autoantibodies in CNS inflammation: MOG and more [PDF]
B cells and antibodies constitute an important element in different inflammatory diseases of the central nervous system (CNS). Autoantibodies can serve as a biomarker to identify disease subgroups and may in addition contribute to the pathogenic process.
Mayer, Marie Cathrin +5 more
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Diffusion-weighted imaging in acute demyelinating myelopathy [PDF]
Diffusion-weighted imaging (DWI) has become a reference MRI technique for the evaluation of neurological disorders. Few publications have investigated the application of DWI for inflammatory demyelinating lesions. The purpose of the study was to describe
Stephan Wetzel +17 more
core +2 more sources
An overall view of the most common experimental models for multiple sclerosis
Multiple sclerosis (MS) is a complex chronic disease with an unknown etiology. It is considered an inflammatory demyelinating and neurodegenerative disorder of the central nervous system (CNS) characterized, in most cases, by an unpredictable onset of ...
S. Dedoni +8 more
doaj +1 more source

