Results 1 to 10 of about 271,555 (310)
Parvalbumin basket cell myelination accumulates axonal mitochondria to internodes
How myelin controls energy usage in different neuronal cell types remains unclear. Here, using viral tools, live imaging and ultrastructural data, the authors show that in contrast to excitatory axons interneuron myelination boosts the clustering of ...
Koen Kole +4 more
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Constitutively active SARM1 variants that induce neuropathy are enriched in ALS patients
Background In response to injury, neurons activate a program of organized axon self-destruction initiated by the NAD+ hydrolase, SARM1. In healthy neurons SARM1 is autoinhibited, but single amino acid changes can abolish autoinhibition leading to ...
A. Joseph Bloom +5 more
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Polineuropatia do paciente crítico: registro de caso [PDF]
A polineuropatia do paciente crítico é de natureza axonal, aguda e de predomínio motor, desenvolvendo-se em pacientes sépticos ou com falência de múltiplos órgãos que geralmente necessitam de ventilação mecânica em unidade de tratamento intensivo.
LUÍZA BEATRIZ A. M. ALVIM +3 more
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Axonal degeneration in association with carpal tunnel syndrome [PDF]
Median nerve entrapment in the palm to wrist segment is known as carpal tunnel syndrome (CTS). Electromyography is the best evaluation test to confirm the disease, as it shows a median reduced conduction velocity and/or conduction block; however, the ...
Marcelo Ribeiro Caetano
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Objective: One or more inexcitable motor (IM) nerves are common during electrodiagnostic (EDx) study in Guillain–Barré syndrome (GBS). This study assessed the dose–effect relationship of IM nerves on outcome in patients with acute inflammatory ...
Mritunjai Kumar +3 more
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Elevated Axonal Protein Markers Following Repetitive Blast Exposure in Military Personnel
Blast exposures that occur during training are common in military personnel; however, the biomarkers that relate to these subtle injuries is not well understood.
Rany Vorn +7 more
doaj +1 more source
Acute Onset Chronic Inflammatory Demyelinating Polyneuropathy Following COVID-19
The cases of Guillain Barre Syndrome (GBS) have been reported following the coronavirus disease 2019 (COVID-19). Here, we describe a case that evolved from GBS to chronic inflammatory demyelinating polyneuropathy (CIDP) after COVID-19 in terms of ...
Nilgün Çınar +4 more
doaj +1 more source
Therapeutic repair for spinal cord injury: combinatory approaches to address a multifaceted problem
The recent years saw the advent of promising preclinical strategies that combat the devastating effects of a spinal cord injury (SCI) that are progressing towards clinical trials.
Jarred M Griffin, Frank Bradke
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Parvalbumin-positive (PV+) γ-aminobutyric acid (GABA) interneurons are critically involved in producing rapid network oscillations and cortical microcircuit computations, but the significance of PV+ axon myelination to the temporal features of inhibition
Mohit Dubey +6 more
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Normal Cortical Myelination in Galectin-4-Deficient Mice
Myelin, critical for the correct function of the nervous system, is organized in different patterns that can include long non-myelinated axonal segments. How myelin patterning is regulated remains unexplained. The carbohydrate-binding protein galectin-4 (
María Elvira Brocca +8 more
doaj +1 more source

