Results 1 to 10 of about 271,555 (310)

Parvalbumin basket cell myelination accumulates axonal mitochondria to internodes

open access: yesNature Communications, 2022
How myelin controls energy usage in different neuronal cell types remains unclear. Here, using viral tools, live imaging and ultrastructural data, the authors show that in contrast to excitatory axons interneuron myelination boosts the clustering of ...
Koen Kole   +4 more
doaj   +1 more source

Constitutively active SARM1 variants that induce neuropathy are enriched in ALS patients

open access: yesMolecular Neurodegeneration, 2022
Background In response to injury, neurons activate a program of organized axon self-destruction initiated by the NAD+ hydrolase, SARM1. In healthy neurons SARM1 is autoinhibited, but single amino acid changes can abolish autoinhibition leading to ...
A. Joseph Bloom   +5 more
doaj   +1 more source

Polineuropatia do paciente crítico: registro de caso [PDF]

open access: yesArquivos de Neuro-Psiquiatria, 1999
A polineuropatia do paciente crítico é de natureza axonal, aguda e de predomínio motor, desenvolvendo-se em pacientes sépticos ou com falência de múltiplos órgãos que geralmente necessitam de ventilação mecânica em unidade de tratamento intensivo.
LUÍZA BEATRIZ A. M. ALVIM   +3 more
doaj   +1 more source

Axonal degeneration in association with carpal tunnel syndrome [PDF]

open access: yesArquivos de Neuro-Psiquiatria, 2003
Median nerve entrapment in the palm to wrist segment is known as carpal tunnel syndrome (CTS). Electromyography is the best evaluation test to confirm the disease, as it shows a median reduced conduction velocity and/or conduction block; however, the ...
Marcelo Ribeiro Caetano
doaj   +1 more source

Dose–Effect relationship of motor nerve inexcitability on outcome in guillain–Barré syndrome: A prospective cohort study

open access: yesAnnals of Indian Academy of Neurology, 2023
Objective: One or more inexcitable motor (IM) nerves are common during electrodiagnostic (EDx) study in Guillain–Barré syndrome (GBS). This study assessed the dose–effect relationship of IM nerves on outcome in patients with acute inflammatory ...
Mritunjai Kumar   +3 more
doaj   +1 more source

Elevated Axonal Protein Markers Following Repetitive Blast Exposure in Military Personnel

open access: yesFrontiers in Neuroscience, 2022
Blast exposures that occur during training are common in military personnel; however, the biomarkers that relate to these subtle injuries is not well understood.
Rany Vorn   +7 more
doaj   +1 more source

Acute Onset Chronic Inflammatory Demyelinating Polyneuropathy Following COVID-19

open access: yesDüzce Tıp Fakültesi Dergisi, 2022
The cases of Guillain Barre Syndrome (GBS) have been reported following the coronavirus disease 2019 (COVID-19). Here, we describe a case that evolved from GBS to chronic inflammatory demyelinating polyneuropathy (CIDP) after COVID-19 in terms of ...
Nilgün Çınar   +4 more
doaj   +1 more source

Therapeutic repair for spinal cord injury: combinatory approaches to address a multifaceted problem

open access: yesEMBO Molecular Medicine, 2020
The recent years saw the advent of promising preclinical strategies that combat the devastating effects of a spinal cord injury (SCI) that are progressing towards clinical trials.
Jarred M Griffin, Frank Bradke
doaj   +1 more source

Myelination synchronizes cortical oscillations by consolidating parvalbumin-mediated phasic inhibition

open access: yeseLife, 2022
Parvalbumin-positive (PV+) γ-aminobutyric acid (GABA) interneurons are critically involved in producing rapid network oscillations and cortical microcircuit computations, but the significance of PV+ axon myelination to the temporal features of inhibition
Mohit Dubey   +6 more
doaj   +1 more source

Normal Cortical Myelination in Galectin-4-Deficient Mice

open access: yesCells, 2022
Myelin, critical for the correct function of the nervous system, is organized in different patterns that can include long non-myelinated axonal segments. How myelin patterning is regulated remains unexplained. The carbohydrate-binding protein galectin-4 (
María Elvira Brocca   +8 more
doaj   +1 more source

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