Results 11 to 20 of about 271,555 (310)

Neuroinflammation by cytotoxic T-lymphocytes impairs retrograde axonal transport in an oligodendrocyte mutant mouse. [PDF]

PLoS ONE, 2012
Mice overexpressing proteolipid protein (PLP) develop a leukodystrophy-like disease involving cytotoxic, CD8+ T-lymphocytes. Here we show that these cytotoxic T-lymphocytes perturb retrograde axonal transport.
Chi Wang Ip, Antje Kroner, Janos Groh, Marianne Huber, Dennis Klein, Irene Spahn, Ricarda Diem, Sarah K Williams, Klaus-Armin Nave, Julia M Edgar, Rudolf Martini   +10 more
doaj   +2 more sources

Reversible Axonal Dystrophy by Calcium Modulation in Frataxin-Deficient Sensory Neurons of YG8R Mice [PDF]

Frontiers in Molecular Neuroscience, 2017
Friedreich’s ataxia (FRDA) is a peripheral neuropathy involving a loss of proprioceptive sensory neurons. Studies of biopsies from patients suggest that axonal dysfunction precedes the death of proprioceptive neurons in a dying-back process.
Belén Mollá, Belén Mollá, Diana C. Muñoz-Lasso, Diana C. Muñoz-Lasso, Diana C. Muñoz-Lasso, Diana C. Muñoz-Lasso, Fátima Riveiro, Fátima Riveiro, Arantxa Bolinches-Amorós, Arantxa Bolinches-Amorós, Federico V. Pallardó, Federico V. Pallardó, Federico V. Pallardó, Angel Fernandez-Vilata, María de la Iglesia-Vaya, María de la Iglesia-Vaya, María de la Iglesia-Vaya, Francesc Palau, Francesc Palau, Francesc Palau, Pilar Gonzalez-Cabo, Pilar Gonzalez-Cabo, Pilar Gonzalez-Cabo   +22 more
doaj   +2 more sources

Axonal Computations [PDF]

Frontiers in Cellular Neuroscience, 2019
25 pages, 6 ...
Pepe Alcami, Pepe Alcami, Ahmed El Hady, Ahmed El Hady   +3 more
openaire   +6 more sources

Axon Physiology [PDF]

Physiological Reviews, 2011
Axons are generally considered as reliable transmission cables in which stable propagation occurs once an action potential is generated. Axon dysfunction occupies a central position in many inherited and acquired neurological disorders that affect both peripheral and central neurons.
Debanne, Dominique, Campanac, Emilie, Bialowas, Andrzej, Carlier, Edmond, Alcaraz, Gisèle   +4 more
openaire   +3 more sources

Nondirected axonal growth on basal lamina from avian embryonic neural retina [PDF]

, 1987
The vitreous surface of the embryonic avian retinal neuroepithelium was isolated by mechanical disruption of the retina mounted between 2 adhesive substrata.
Kröger, Stephan, Kröger, S. ; https://orcid.org/, Reckhaus, W., W Halfter, W Reckhaus, S Kroger, Halfter, W.   +6 more
core   +2 more sources

Traumatic axonal injury in the spinal cord evoked by traumatic brain injury [PDF]

, 2008
Although it is well known that traumatic brain injury (TBI) evokes traumatic axonal injury (TAI) within the brain, TBI-induced axonal damage in the spinal cord (SC) has been less extensively investigated.
Czeiter, Endre,, Dóczi, Tamás, Luckl, Janos,, Doczi, Tamas,, Kovesdi, Erzsebet,, Büki, András, Pál, József, Pal, Jozsef,, Czeiter, Endre, Bukovics, Peter,, Kövesdi, Erzsébet, Lückl, János, Büki, Andras,, Bukovics, Péter   +13 more
core   +1 more source

Tri-partite complex for axonal transport drug delivery achieves pharmacological effect. [PDF]

, 2010
BACKGROUND: Targeted delivery of pharmaceutical agents into selected populations of CNS (Central Nervous System) neurons is an extremely compelling goal.
Sokoloff Alan J, Miri D Rabinowitz, Munglani, Raj, Filler, Aaron G, Filler, A.G, Munglani, R, Chris Abell, Rabinowitz, Miri D, Terrence W Deacon, Andrew ML Lever, Deacon Terrence W, Munglani Raj, Mark Bacon, Sokoloff, Alan J, Franklyn A Howe, Deacon, T.W, Whiteside, Garth T, Bacon, Mark, Howe, F.A, Abell, Chris, Sokoloff, AJ, Griffiths, J.R, Filler Aaron G, Lever, Andrew ML, Howe, FA, Alan J Sokoloff, Martyn Frederickson, Bell B Anthony, Bell, B.A, Bacon, M, Frederickson Martyn, Garth T Whiteside, Griffiths, John R, Abell, C, Aaron G Filler, B Anthony Bell, Griffiths John R, Rabinowitz Miri D, Bacon Mark, Bell, B Anthony, Lever, A.M.L, Frederickson, Martyn, Filler, AG, Abell Chris, Sokoloff, A.J, Frederickson, M, John R Griffiths, Lever Andrew ML, Whiteside Garth T, Deacon, Terrence W, Bell, BA, Whiteside, GT, Griffiths, JR, Rabinowitz, MD, Deacon, TW, Lever, AM, Whiteside, G.T, Howe Franklyn A, Howe, Franklyn A, Raj Munglani, Rabinowitz, M.D   +60 more
core   +3 more sources

Axonal Regeneration Through Autologous Grafts: Does the Axonal Load Influence Regeneration? [PDF]

, 2022
INTRODUCTION Two-stage free functional muscle transfers for long-standing facial palsy can yield unpredictable results. Earlier studies have demonstrated incomplete regeneration across neurorrhaphies in native nerve and higher donor axonal counts ...
Leckenby, Jonathan I, Milek, David, Grobbelaar, Adriaan O, Lichtman, Jeff W, Chacon, Miranda A   +4 more
core   +1 more source

Axonal transport during injury on a theoretical axon

Frontiers in Cellular Neuroscience, 2023
Neurodevelopment, plasticity, and cognition are integral with functional directional transport in neuronal axons that occurs along a unique network of discontinuous polar microtubule (MT) bundles. Axonopathies are caused by brain trauma and genetic diseases that perturb or disrupt the axon MT infrastructure and, with it, the dynamic interplay of motor ...
Soumyadeep Chandra, Rounak Chatterjee, Zachary T. Olmsted, Zachary T. Olmsted, Amitava Mukherjee, Amitava Mukherjee, Janet L. Paluh   +6 more
openaire   +3 more sources

Live axonal transport disruption by mutant huntingtin fragments in Drosophila motor neuron axons [PDF]

, 2009
Huntington's Disease is a neurodegenerative condition caused by a polyglutamine expansion in thehuntingtin (Htt) protein, which aggregates and also causes neuronal dysfunction. Pathogenic N-terminal httfragments perturb axonal transport in vitro.
Burbidge-King, T., Thompson, LM, Sinadinos, Christopher, Sinadinos, C, Marsh, J.L, Soh, D, Wyttenbach, Andreas, Mudher, Amritpal, Wyttenbach, A, Marsh, JL, Soh, D., Burbidge-King, T, Mudher, AK, Thompson, L.M.   +13 more
core   +1 more source