Results 121 to 130 of about 4,914,110 (289)

A Tripartite Model for EBV‐Driven Multiple Sclerosis: B Cell Survival, Altered Self‐Presentation, and HLA‐DR15‐Restricted T Cell Cross‐Reactivity

iNew Medicine, EarlyView.
ABSTRACT This commentary integrates findings from three recent Cell reports to establish a unified mechanistic model of multiple sclerosis (MS) driven by the interplay between Epstein‐Barr virus (EBV) and the HLA‐DR15 genotype. EBV promotes CNS autoimmunity through three distinct but intersecting mechanisms.
Fang Zhu, Arnaud John Kombe Kombe, Tengchuan Jin   +2 more
wiley   +1 more source

Fifth disease (slapped cheek syndrome)

, 2015
What is fifth disease Fifth disease, which is also known as ?slapped cheek syndrome? or erythema infectiosum is a common viral infection caused by parvovirus B19.
Centre for Disease Control
core  

The regulation of stem cell fate and its application in neural regeneration

Interdisciplinary Medicine, EarlyView.
Regulating stem cell fate is crucial for neural regeneration. This review summarizes key physical, biological, and chemical strategies and their applications in repairing nerve injuries, providing new insights for regenerative medicine. Abstract Regulating the fate of stem cells (SCs) is a key technical problem in the field of regenerative medicine and
Yuexin He, Xingyu Chen, Minghong He, Zhe Li   +3 more
wiley   +1 more source

Anti-NMDAR Antibodies in Demyelinating Diseases

, 2017
Introduction: Antibodies against N-methyl D-aspartate receptor (anti-NMDAR) are directly pathogenic autoantibodies associated with encephalitis. Cases reporting the presence of anti-NMDAR antibodies associated with a demyelinating disease have been ...
Elisak, M., Marusic, P., Liskova, P., Ivana Štětkářová, Krysl, David,, Petr Marusič, Hanzalova, J., Meluzinova, E., I. Doležalová, Stetkarova, I., Martin Elišák, J. Hanzalová, Petra Lišková, Eva Meluzínová, David Krýsl, Dolezalova, I.   +15 more
core   +1 more source

Multiparametric Quantitative MRI of Peripheral Nerves to Differentiate Demyelinating From Axonal Polyneuropathies

Journal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Background Differentiating demyelinating from axonal polyneuropathies helps for accurate diagnosis and treatment. However, the current clinical tools lack sensitivity to confirm demyelination in peripheral nerves, particularly for proximal nerves.
Jesus E. Fajardo, Vivian B. Truong, Yang Xuan, Sara E. Benitez, Mary L. Vo, Bo Hu, Richard D. Dortch, Jun Li, Yongsheng Chen   +8 more
wiley   +1 more source

Post COVID-19 Demyelinating Disease

, 2020
Post COVID-19 Demyelinating Disease Daniel Lopez, MD1, Nicole Irizarry, MD2, Daniel Martinez, MD3 Isabel Brea, MD4 1Emergency Medicine Resident PGY-1, Kendall Regional Medical Center 2Emergency Medicine Teaching Faculty, Kendall Regional Medical ...
Irizarry, Nicole, Lopez, Daniel J
core   +1 more source

Leptospira infection complicated by demyelinating disease: A case report. [PDF]

Front Neurol, 2022
Chen SX, Han DK, Liu Y, Ye ZH, Lu K, Xu B, Mai HQ.   +6 more
europepmc   +1 more source

Semliki Forest virus induced, immune mediated demyelination: the effect of irradiation [PDF]

, 1987
Intraperitoneal infection with the avirulent A7(74) strain of the alphavirus Semliki Forest virus (SFV) induces an immune mediated demyelinating encephalomyelitis.
Fazakerley, J K, Webb, H E
core  

The Hidden Burden of Hemifacial Spasm: A Systematic Review of Non‐Motor Symptoms

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Hemifacial spasm (HFS) is a chronic neurological disorder characterized by involuntary contractions of facial muscles. Traditionally regarded as a motor condition, HFS encompasses a spectrum of non‐motor symptoms that are often overlooked but significantly affect patients’ quality of life.
Miriam Carvalho Soares, Jacy Bezerra Parmera, Pedro Augusto Sampaio Rocha‐Filho   +2 more
wiley   +1 more source

Myelin insulation as a risk factor for axonal degeneration in autoimmune demyelinating disease. [PDF]

Nat Neurosci, 2023
Schäffner E, Bosch-Queralt M, Edgar JM, Lehning M, Strauß J, Fleischer N, Kungl T, Wieghofer P, Berghoff SA, Reinert T, Krueger M, Morawski M, Möbius W, Barrantes-Freer A, Stieler J, Sun T, Saher G, Schwab MH, Wrede C, Frosch M, Prinz M, Reich DS, Flügel A, Stadelmann C, Fledrich R, Nave KA, Stassart RM.   +26 more
europepmc   +1 more source