Results 171 to 180 of about 4,914,110 (289)

MyD88‐Family Adaptors: Compartmentalised Signalling and Non‐Immune Functions

Immunology, EarlyView.
MyD88‐family adaptors coordinate receptor‐ and compartment‐specific innate immune signalling across plasma membrane and endosomal pathways. At the plasma membrane, TIRAP/MAL supports MyD88‐dependent signalling downstream of TLR2 and TLR4, whereas endosomal TLR7, TLR8 and TLR9 recruit MyD88 directly.
Seshu Vardhan Pothabathula, Saurabh Mishra, Pugazhendhi Kannan, Annette Bellar, Amy Attaway, Nicole Welch, Srinivasan Dasarathy   +6 more
wiley   +1 more source

Mosaic STAT5B gain-of-function associated with demyelinating disease and autoimmunity. [PDF]

J Hum Immun
Schmitt EG, Saucier N, Risma SI, Arbag SN, Kolicheski A, Paul AJ, Toler TL, Semkiu K, Mar SS, Milner JD, Bednarski JJ, Cooper MA.   +11 more
europepmc   +1 more source

Tumor necrosis factor alpha inhibitors and demyelinating disease: what is behind it? [PDF]

Reumatologia, 2021
Kucharz EJ, Kotulska-Kucharz A.
europepmc   +1 more source

Neuroanatomy education through the years: Revisiting the teaching slides used by Sir Wilfrid Edward Le Gros Clark

Journal of Anatomy, EarlyView.
This paper examines the life and legacy of British anatomist Sir Wilfrid Le Gros Clark through his neuroanatomical teaching collection at the University of Oxford. The authors catalogued 103 specimens and analyzed selected slides—including cases of multiple sclerosis, amyotrophic lateral sclerosis, tabes dorsalis, syringomyelia, and the pineal gland's ...
Shiva A. Nischal, Kush M. Kale, Katherine Tourigny, Mohammed Abuelem, Gretchen Greene, Rachel Walsh, Zoltán Molnár   +6 more
wiley   +1 more source

Low-Positive Myelin Oligodendrocyte Glycoprotein (MOG)-Immunoglobulin G (IgG) in Pediatric Demyelinating Disease: How Imaging Features Can Support a MOG Antibody-Associated Disease (MOGAD) Diagnosis. [PDF]

Cureus
Tang CL, Fok EWS.
europepmc   +1 more source

Biological aging of CNS-resident cells alters the clinical course and immunopathology of autoimmune demyelinating disease. [PDF]

JCI Insight, 2022
Atkinson JR, Jerome AD, Sas AR, Munie A, Wang C, Ma A, Arnold WD, Segal BM.   +7 more
europepmc   +1 more source

Copper Deficiency-Induced Neuropathy After Bariatric Surgery Disguised as Demyelinating Disease: A Case Report. [PDF]

Cureus, 2022
Amin A, Khoury NC, Lacayo M, Kostanyan S.   +3 more
europepmc   +1 more source

Efficacy and safety of high doses of eltrombopag for treating adult immune thrombocytopenia: Results from a multicentre retrospective cohort study

British Journal of Haematology, EarlyView.
Salomé Dahan, Stéphanie Guillet, Olivier Fain, Delphine Gobert, Stéphane Cheze, Florent Broca, Bertrand Godeau, Marc Michel   +7 more
wiley   +1 more source

Narcolepsy and rapid eye movement sleep

Journal of Sleep Research, Volume 34, Issue 2, April 2025.
Summary Since the first description of narcolepsy at the end of the 19th Century, great progress has been made. The disease is nowadays distinguished as narcolepsy type 1 and type 2. In the 1960s, the discovery of rapid eye movement sleep at sleep onset led to improved understanding of core sleep‐related disease symptoms of the disease (excessive ...
Francesco Biscarini, Lucie Barateau, Fabio Pizza, Giuseppe Plazzi, Yves Dauvilliers   +4 more
wiley   +1 more source

Addendum: Myelin insulation as a risk factor for axonal degeneration in autoimmune demyelinating disease. [PDF]

Nat Neurosci
Schäffner E, Bosch-Queralt M, Edgar JM, Lehning M, Strauß J, Fleischer N, Kungl T, Wieghofer P, Berghoff SA, Reinert T, Krueger M, Morawski M, Möbius W, Barrantes-Freer A, Stieler J, Sun T, Saher G, Schwab MH, Wrede C, Frosch M, Prinz M, Reich DS, Flügel A, Stadelmann C, Fledrich R, Nave KA, Stassart RM.   +26 more
europepmc   +1 more source