Macrophages and Autoantibodies in Demyelinating Diseases [PDF]
Cells, 2021 Myelin phagocytosis by macrophages has been an essential feature of demyelinating diseases in the central and peripheral nervous systems, including Guillain–Barré syndrome (GBS), chronic inflammatory demyelinating polyneuropathy (CIDP), and multiple ...
Haruki Koike, Masahisa Katsuno
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Advances in Therapeutics Research for Demyelinating Diseases [PDF]
PharmaceuticalsDemyelinating diseases comprise a group of chronic and debilitating neurological disorders, with the destruction of the myelin sheath serving as the core pathological hallmark. The central pathogenesis involves immune-mediated damage to oligodendrocytes (
Jinhui Jiang +5 more
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COVID-19 and the risk of CNS demyelinating diseases: A systematic review [PDF]
Frontiers in Neurology, 2022 BackgroundViral infections are a proposed possible cause of inflammatory central nervous system (CNS) demyelinating diseases, including multiple sclerosis (MS), neuromyelitis optica spectrum disorder (NMOSD), and myelin oligodendrocyte glycoprotein ...
Itay Lotan +4 more
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Therapeutic potential of neuromodulation for demyelinating diseases
Neural Regeneration Research, 2021 Neuromodulation represents a cutting edge class of both invasive and non-invasive therapeutic methods which alter the activity of neurons. Currently, several different techniques have been developed - or are currently being investigated – to treat a wide
Elliot H Choi +5 more
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Demyelinating Diseases: From Molecular Mechanisms to Therapeutic Strategies. [PDF]
Int J Mol Sci, 2023 Demyelinating diseases are a group of pathologies characterized by the alteration of myelin-that is, the coating that wraps around most of the nerve fibres of the central and peripheral nervous system, whose goal is the improvement of nerve conduction ...
Bernardo A, Visentin S.
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Central nervous system demyelinating diseases: glial cells at the hub of pathology. [PDF]
Front Immunol, 2023 Inflammatory demyelinating diseases (IDDs) are among the main causes of inflammatory and neurodegenerative injury of the central nervous system (CNS) in young adult patients.
Coutinho Costa VG +3 more
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Polycaprolactone/graphene oxide/acellular matrix nanofibrous scaffolds with antioxidant and promyelinating features for the treatment of peripheral demyelinating diseases. [PDF]
J Mater Sci Mater Med, 2023 Peripheral demyelinating diseases entail damage to axons and Schwann cells in the peripheral nervous system. Because of poor prognosis and lack of a cure, this group of diseases has a global impact. The primary underlying cause of these diseases involves
Nagarajan A +8 more
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Nuclear hormone receptors in demyelinating diseases. [PDF]
J Neuroendocrinol, 2022 Demyelination results from the pathological loss of myelin and is a hallmark of many neurodegenerative diseases. Despite the prevalence of demyelinating diseases, there are no disease modifying therapies that prevent the loss of myelin or promote ...
Zorrilla Veloz RI +3 more
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The Role of Visual Evoked Potentials in the Differential Diagnosis of Demyelinating Diseases
Türk Nöroloji Dergisi, 2021 Objective: Demyelinating diseases are included in the differential diagnosis of non-specific white matter lesions (NSWMLs), which are incidentally detected by magnetic resonance imaging (MRI) of the brain.
Nurhan Kaya Tutar +4 more
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Diffusion Weighted Imaging versus Contrast- enhanced T1-weighted Imaging Sequences in Inflammatory Demyelinating Diseases of Brain: A Cross-sectional Study [PDF]
International Journal of Anatomy Radiology and Surgery, 2022 Introduction: Based on the literature, Contrast-enhanced T1- Weighted (CE T1WI) imaging sequence is considered as the gold standard radiological marker of active inflammatory demyelinating diseases of brain.
KR Manohar Kumar +2 more
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