Results 101 to 110 of about 9,029,710 (297)
The microglial "activation" continuum: from innate to adaptive responses [PDF]
, 2005 Microglia are innate immune cells of myeloid origin that take up residence in the central nervous system (CNS) during embryogenesis. While classically regarded as macrophage-like cells, it is becoming increasingly clear that reactive microglia play more ...
Nikolic, Veljko +2 more
core +3 more sources
Анналы клинической и экспериментальной неврологии, 2018 Optical coherence tomography (OCT) is a non-invasive technique routinely used for obtaining in vivo transverse images of tissues. In the field of neurology, OCT is used to assess retinal changes in various diseases, including multiple sclerosis ...
Natalia V. Polekhina +2 more
doaj +1 more source
Forecasting Disease Burden In Philippines: A Symbolic Regression Analysis [PDF]
arXiv, 2021 Burden of disease measures the impact of living with illness and injury and dying prematurely and it is increasing worldwide leading cause of death both global and national. This paper aimed to propose an index of diseases and evaluate a mathematical model to describe the number of burden of disease by cause in the Philippines from 1990 - 2016. Through
arxiv
What Does Iron Mean to an Oligodendrocyte?
Glia, EarlyView.ABSTRACT Iron is essential for life and plays a key role in multiple fundamental cellular functions. The brain has the highest rate of energy consumption, and within the brain, oligodendrocytes have the highest level of oxidative metabolism per volume. Oligodendrocytes also stain the strongest for iron.
Quinn W. Wade, James R. Connor
wiley +1 more source
P2T2: a Physically-primed deep-neural-network approach for robust $T_{2}$ distribution estimation from quantitative $T_{2}$-weighted MRI [PDF]
arXiv, 2022 Estimating $T_2$ relaxation time distributions from multi-echo $T_2$-weighted MRI ($T_2W$) data can provide valuable biomarkers for assessing inflammation, demyelination, edema, and cartilage composition in various pathologies, including neurodegenerative disorders, osteoarthritis, and tumors.
arxiv
Glia, EarlyView.ABSTRACT Multiple sclerosis (MS) is the most common non‐infectious inflammatory CNS disease, characterized by progressive neurodegeneration and focal demyelinated lesions. Traditionally considered an autoimmune disease, MS is driven by the immune system's attack on CNS myelin, resulting in cumulative disability.
Volker Siffrin
wiley +1 more source
Concurrent TNFRSF1A R92Q and pyrin E230K mutations in a child with multiple sclerosis [PDF]
, 2010 We report a 16-year-old female patient with a severe course of multiple sclerosis and concomitant symptoms suggestive of a hereditary autoinflammatory disease.
Blaschek, Astrid +7 more
core +1 more source
The effect of realistic geometries on the susceptibility-weighted MR signal in white matter [PDF]
, 2017 Purpose: To investigate the effect of realistic microstructural geometry on the susceptibility-weighted magnetic resonance (MR) signal in white matter (WM), with application to demyelination. Methods: Previous work has modeled susceptibility-weighted signals under the assumption that axons are cylindrical. In this work, we explore the implications of
arxiv +1 more source
Investigating the role of SARM1 in central nervous system
Ibrain, EarlyView.Sterile‐α and Toll/interleukin 1 receptor (TIR) motif‐containing protein 1 (SARM1) is a pivotal molecule that has garnered extensive attention in neuroscience. As an intracellular molecule, SARM1 possesses various crucial biological functions in the nervous system.
Junjie Wang +4 more
wiley +1 more source
Neurological complications of immune checkpoint inhibitors: what happens when you \u27take the brakes off\u27 the immune system. [PDF]
, 2018 Patients with advanced malignancies treated with immune checkpoint inhibitors are at increased risk for developing immune-related neurological complications.
Dalakas, Marinos
core +1 more source