Results 131 to 140 of about 9,029,710 (297)

Investigation of neuro‐vascular reactivity on fMRI study during visual activation in people with multiple sclerosis using EEG and hypercapnia challenge

Medical Physics, EarlyView.
Abstract Background People with multiple sclerosis (MS) exhibit a different pattern of blood oxygenation level‐dependent (BOLD) activation on functional magnetic resonance imaging (fMRI) studies when compared to healthy control (HC). Purpose The objective of this study is to determine whether observed differences in BOLD activation between people with ...
Wanyong Shin, Balu Krishnan, Ajay Nemani, Daniel Ontaneda, Mark J. Lowe   +4 more
wiley   +1 more source

Clinical course, therapeutic responses and outcomes in relapsing MOG antibody-associated demyelination. [PDF]

, 2018
OBJECTIVE: We characterised the clinical course, treatment and outcomes in 59 patients with relapsing myelin oligodendrocyte glycoprotein (MOG) antibody-associated demyelination.
Australasian and New Zealand MOG Study Group Andrews, P, Barnett, Mh, Barton, J, Brilot, F, Broadley, S, Burrow, J, Butzkueven, H, Cairns, A, Calvert, S, Caruana, P, Chelakkadan, S, Clark, D, Dale, Rc, Fraser, C, Freeman, J, Fung, Vsc, Gill, D, Grattan-Smith, P, Gupta, S, Hardy, T, Henderson, Apd, Kothur, K, Lechner-Scott, J, Ling, S, Lopez, J, Malone, S, Marriott, M, Merheb, V, Mohammad, S, Nguyen, Tk, Nosadini, M, O'grady, G, Orr, C, Ouvrier, R, Parratt, J, Patrick, E, Pilli, D, Ramanathan, S, Reddel, Sw, Riminton, D, Riney, K, Rodriguez-Casero, V, Ryan, M, Scheffer, I, Shah, U, Shuey, N, Spooner, C, Subramanian, G, Tantsis, E, Tea, F, Thomas, T, Thompson, J, Troedson, C, Vucic, S, Ware, T, Webster, R, White, Ob, Yiannikas, C, Yiu, E, Zou, A.   +59 more
core   +1 more source

Magnetization transfer imaging using non‐balanced SSFP at ultra‐low field

Magnetic Resonance in Medicine, EarlyView.
Abstract Purpose Ultra‐low field MRI scanners have the potential to improve health care delivery, both through improved access in areas where there are few MRI scanners and allowing more frequent monitoring of disease progression and treatment response.
Sharada Balaji, Neale Wiley, Adam Dvorak, Francesco Padormo, Rui P. A. G. Teixiera, Megan E. Poorman, Alex MacKay, Tobias Wood, Adam R. Cassidy, Anthony Traboulsee, David K. B. Li, Irene Vavasour, Steven C. R. Williams, Sean C. L. Deoni, Emil Ljungberg, Shannon H. Kolind   +15 more
wiley   +1 more source

Placental Mesenchymal Stem Cell-Derived Extracellular Vesicles Promote Myelin Regeneration in an Animal Model of Multiple Sclerosis. [PDF]

, 2019
Mesenchymal stem/stromal cells (MSCs) display potent immunomodulatory and regenerative capabilities through the secretion of bioactive factors, such as proteins, cytokines, chemokines as well as the release of extracellular vesicles (EVs).
Barthe, Sylvain, Clark, Kaitlin, Farmer, Diana, Guo, Fuzheng, Kreutzberg, Nicole, Kumar, Priyadarsini, Paxton, Zachary, Pivetti, Christopher, Reed, Camille, Wang, Aijun, Wang, Yan, Zhang, Sheng   +11 more
core   +2 more sources

Quantitative susceptibility mapping in magnetically inhomogeneous tissues

Magnetic Resonance in Medicine, EarlyView.
Abstract Purpose Conventional quantitative susceptibility mapping (QSM) methods rely on simplified physical models that assume isotropic and homogeneous tissue properties, leading to artifacts and inaccuracies in biological tissues. This study aims to develop and evaluate DEEPOLE, a deep learning–based method that incorporates macroscopically ...
Thomas Jochmann, Fahad Salman, Michael G. Dwyer, Niels Bergsland, Robert Zivadinov, Jens Haueisen, Ferdinand Schweser   +6 more
wiley   +1 more source

Efficacy and safety of Privigen® in patients with chronic inflammatory demyelinating polyneuropathy: results of a prospective, single-arm, open-label Phase III study (the PRIMA study) [PDF]

, 2013
This prospective, multicenter, single-arm, open-label Phase III study aimed to evaluate the efficacy and safety of Privigen (R) (10% liquid human intravenous immunoglobulin [IVIG], stabilized with l-proline) in patients with chronic inflammatory ...
Bauhofer, Artur, De Bleecker, Jan, Kamienowski, Jerzy, Léger, Jean-Marc, Merkies, Ingemar SJ, Mielke, Orell, Robberecht, Wim, Saarela, Mika, Shebl, Amgad, Sommer, Claudia, Stelmasiak, Zbigniew, Tackenberg, Björn, Zenker, Othmar   +12 more
core   +1 more source

Tumefactive Brain Demyelination Accompanying MADSAM Neuropathy

Türk Nöroloji Dergisi, 2015
Multifocal acquired demyelinating sensory and motor (MADSAM) neuropathy is characterized by asymmetric multifocal motor and sensory loss and conduction blocks in peripheral nerves.
Şefik Evren Erdener, Çağrı Mesut Temuçin, Figen Söylemezoğlu, Rahşan Göçmen, Aslı Tuncer Kurne   +4 more
doaj   +1 more source

Peripheral Nervous System Involvement of Hereditary Transthyretin Amyloidosis in the United States: A Multi‐Center Perspective

Muscle &Nerve, EarlyView.
ABSTRACT Introduction/Aims Hereditary transthyretin amyloidosis (ATTRv) is an autosomal dominant multisystem disorder that occurs worldwide. The most common mutation in the United States, V142I, has previously been described as having a primarily cardiac presentation.
Urvi Desai, Hristelina S. Ilieva, James E. Eyer, Amanda C. Peltier   +3 more
wiley   +1 more source

Five decades of cuprizone, an updated model to replicate demyelinating diseases [PDF]

, 2017
: Introduction: Demyelinating diseases of the central nervous system (CNS) comprise a group of neurological disorders characterized by progressive (and eventually irreversible) loss of oligodendrocytes and myelin sheaths in the white matter tracts.
GONZALEZ PEREZ, OSCAR, GONZALEZ PEREZ, OSCAR, MENDEZ VICTORIANO, GERARDO, MENDEZ VICTORIANO, GERARDO, MORALES LUCKIE, RAUL ALBERTO, MORALES LUCKIE, RAUL ALBERTO, VEGA RIQUER, JOSE MANUEL, VEGA RIQUER, JOSE MANUEL   +7 more
core  

Expression and Differential Responsiveness of Central Nervous System Glial Cell Populations to the Acute Phase Protein Serum Amyloid A [PDF]

, 2017
Acute-phase response is a systemic reaction to environmental/inflammatory insults and involves hepatic production of acute-phase proteins, including serum amyloid A (SAA). Extrahepatically, SAA immunoreactivity is found in axonal myelin sheaths of cortex
A Castellheim, A Ellis, AE Mullick, BK Lundholt, BM Schreiber, C Caltagirone, C Gabay, C Marinelli, C Nathan, C Nuccio De, C Rosin, C Solà, C Vaure, CM Uhlar, DB Noriega, DL Thiele, E Gruys, ES Wohleb, F Begum, F Caso, G Guillemin, GC Sellar, GS Getz, GW Duff, H Zheng, HJ Yu, I Hardardóttir, I Paterniti, I Paterniti, I Rajkovic, J Saura, JM Dopp, JS Liang, JT Guo, JW Jeong, J‐L Tchélingérian, K Selmaj, L Facci, L Probert, L Qin, L Sun, M Alhouayek, M Barbierato, M Bsibsi, M Buck De, M Cordaro, M Kopf, M Li, M Poljakovic, ME Hamby, MK McCoy, MS Kindy, N Castanon, N Cheng, N Marchi, P Matzinger, R Martini, RA Dal Canto, RL Meek, RM Ransohoff, S Amor, S Kim, S Lehnardt, S Sandri, S Spuler, SA Liddelow, SD Skaper, SD Skaper, SJ Crocker, SJ Hewett, SY Seong, T Kawamoto, T Miida, TC Theoharides, TF Chung, Y Kumon, Y Yu, YJ Jang   +77 more
core   +2 more sources