Results 211 to 220 of about 56,601 (283)

When Treatment Turns to Stone: Injection‐Site Calcinosis Associated With Interferon‐β in Multiple Sclerosis: A Case Report

Clinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT Injection‐site calcinosis is a rare complication of interferon‐β therapy in multiple sclerosis. We report a 52‐year‐old woman with stable bilateral gluteal calcifications after long‐term subcutaneous interferon‐β‐1b therapy. Findings were most consistent with probable dystrophic calcinosis cutis secondary to chronic repeated injection‐site ...
Anna Walter, Adam Bott, Marianne Kiechle, Margret Hund‐Georgiadis   +3 more
wiley   +1 more source

Spinal Cord Involvement in Neurosarcoidosis: A Case of Longitudinally Extensive Transverse Myelitis at Disease Onset

Clinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT Acute‐onset neurological deficits in otherwise healthy individuals warrant a broad differential diagnosis. Neurosarcoidosis presenting as longitudinally extensive transverse myelitis is rare, mimicking demyelinating, infectious, or neoplastic disorders. Early recognition, histopathological confirmation, and timely immunosuppressive therapy are
Areeb Tiwana, Vicky Elias Nahra, Muhammad Adeel Hassan   +2 more
wiley   +1 more source

A Case of Cerebral Cortical Encephalitis

Annals of Clinical and Translational Neurology, Volume 13, Issue 6, Page 1294-1296, June 2026.
Sixiao Liu, Kunqian Ji, Wei Wu, Wei Li
wiley   +1 more source

Neuromyelitis Optica Spectrum Disorder Following Pituitary Tumor Resection: A Rare but Critical Differential in Neurosurgical Practice

Clinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT Neuromyelitis optica spectrum disorder (NMOSD) is a rare, immune‐mediated astrocytopathy disorder that predominantly affects adults. Postoperative cases are scarcely reported. A 75‐year‐old woman underwent uncomplicated endoscopic resection of a nonfunctional pituitary macro‐adenoma.
Arad Iranmehr, Mohammad Shirani, Abdorreza Naser Moghadasi, Shirin Irani, Narges Akhlaghi, Samira Mirzaei, Hesam Ghadirian   +6 more
wiley   +1 more source

Use of Complementary and Alternative Medicine in Patients With Idiopathic Inflammatory Demyelinating Diseases of the Central Nervous System: A Cross-Sectional Study in Thailand. [PDF]

Curr Ther Res Clin Exp
Kosiyakul P, Jitprapaikulsan J, Rattanathamsakul N, Siritho S, Sangsai O, Aueaphatthanawong K, Engchuan M, Prayoonwiwat N.   +7 more
europepmc   +1 more source

CYP46A1‐Targeted Treatment Alleviates Long‐Term White Matter Injury Following Traumatic Brain Injury by Promoting Cholesterol Metabolic Clearance and Remyelination

CNS Neuroscience &Therapeutics, Volume 32, Issue 6, June 2026.
Our findings demonstrate that CYP46A1 plays a critical role in regulating cholesterol homeostasis in microglia and that the targeting of CYP46A1 may offer a viable therapeutic approach for traumatic brain injury (TBI). The CYP46A1 activator Efavirenz reduces white matter damage by increasing the levels of the cholesterol metabolite 24OHC, thereby ...
Lin Li, You Shi, Qing Luo, Peiwen Guo, Taotao Jin, Xufang Ru, Zhouyang Jiang, Yin Niu, Wenyan Li, Yujie Chen, Zhi Chen   +10 more
wiley   +1 more source

Exercise Intervention for REM Sleep Behavior Disorder in Parkinson's Disease: Mechanisms and Implications for Neurorehabilitation

CNS Neuroscience &Therapeutics, Volume 32, Issue 6, June 2026.
This review systematically explores exercise as a multi‐target intervention for RBD, highlighting its mechanisms of action and regulatory effects on key pathophysiological processes. ABSTRACT Backgrounds REM sleep behavior disorder (RBD) is a prodromal non‐motor symptom of Parkinson's disease (PD) and other α‐synucleinopathies, affecting approximately ...
Xinhui Qiu, Zihui Wang, Ruixue Xu, Yiying Hu, Weidong Le   +4 more
wiley   +1 more source

Growth Differentiation Factor 11 Is a Circulating Regulator of Oligodendrocyte Differentiation and CNS Myelin Formation and Repair

CNS Neuroscience &Therapeutics, Volume 32, Issue 6, June 2026.
Systemically administered GDF11 enhances CNS myelin formation and repair across both developmental and disease contexts. GDF11 promotes the differentiation of oligodendrocyte progenitor cells into mature oligodendrocytes, increases myelin sheath thickness in neonatal mice, and accelerates remyelination in both the cuprizone‐induced demyelination model ...
Zhen Zhang, Min Yan, Wenjiao Huang, Yongchang Chen, Tao Lv, Wenli Chen   +5 more
wiley   +1 more source

Association of Neurodevelopmental Disorders and Congenital Anomalies With Prenatal Multiple Sclerosis Treatment—Real‐World Historical Cohort Study

Clinical Pharmacology &Therapeutics, Volume 119, Issue 6, Page 1565-1573, June 2026.
There is a paucity of data regarding the effects of prenatal disease‐modifying therapies (DMTs) for multiple sclerosis (MS), on congenital anomalies in the offspring. Moreover, data on the association with neurodevelopmental disorders are lacking. This is an historical cohort study, within the Israeli Clalit Health Services database (2005–2024) that ...
Bar Rosh, Ofek Levi, Nili Stein, Amir Yahav, Naomi Gronich   +4 more
wiley   +1 more source

Physiology, pathology and therapeutic potential of microglial triggering receptor expressed on myeloid cells 2 signalling: A narrative update

Clinical and Translational Discovery, Volume 6, Issue 3, June 2026.
TREM2hi microglia and macrophages exert distinct roles in neurological diseases. Enhancing TREM2 signalling supports pathological protein or debris clearance and mitigates inflammation in Alzheimer's disease, Parkinson's disease, amyotrophic lateral sclerosis, demyelination disorders and stroke, whereas blocking TREM2 may alleviate tauopathy and ...
Zhe Kong, Libin Shen, Daqing Ma, Jinchao Hou   +3 more
wiley   +1 more source