Results 101 to 110 of about 131,881 (286)

The effects of temperature, feed ratio, and reaction time on the properties of copolymer PLA-PEG-PLA

Vietnam Journal of Science, Technology and Engineering, 2019
Triblock copolymers were polymerised by the ringopening reaction of D,L-lactide in the presence of poly(ethylene glycol) (PEG), with number-average molecular weight (Mn) of 1500 and 2050 g/mol, using Sn(Oct)2 as a catalyst.
Viet Linh Nguyen-Vu, Mai Anh Pham, Dai Phu Huynh   +2 more
doaj   +1 more source

Denaturation of Heterogeneous DNA

, 1997
The effect of heterogeneous sequence composition on the denaturation of double stranded DNA is investigated. The resulting pair-binding energy variation is found to have a negligible effect on the critical properties of the smooth second order melting ...
A. Yu. Grosberg, B. Derrida, B. H. Zimm, B. H. Zimm, D. Poland, D. Poland, Dinko Cule, E. W. Montroll, G. Forgacs, H. Kallabis, J.-F. Joanny, L. D. Landau, L. Gutman, M. Kardar, M. Peyrard, O. Gotoh, P.-G. de Gennes, R. M. Wartell, R. M. Wartell, S. M. Bhattacharjee, S. Mukherji, S. P. Obukhov, T. Dauxois, T. Dauxois, Terence Hwa   +24 more
core   +1 more source

A Cryoprotectant‐Compatible Nanoporous Platform for Stable and Scalable Delivery of Biopharmaceuticals

Advanced Materials, EarlyView.
A cryoprotectant‐compatible nanoporous platform enables ambient‐stable and scalable delivery of gene editing therapeutics. By combining hierarchical pore architecture with optimized lyophilization chemistry, the system preserves Cas9‐RNP activity post‐freeze‐drying.
Sian Lee, Seongchan Kim, Jooyeun Chong, Min‐gyeong Kim, Kayeong Lim, Nan‐Ee Lee, Jahyun Koo, Jiheong Kang, Hyojin Lee   +8 more
wiley   +1 more source

Synchronizing the Osteochondral Regeneration Process through Spatial Patterning of Stable and Hypertrophic Cartilage Organoids

Advanced Materials, EarlyView.
Zonated osteochondral assembloid implants are engineered through scaffold‐free spatial assembly of induced pluripotent stem cell (iPSC)‐derived chondrocyte organoids and periosteum‐derived osteogenic organoids. Implanted into full‐thickness rat osteochondral defects, they promote hyaline‐like cartilage repair, support subchondral bone formation with ...
Liuqi Peng, Isaak Decoene, Hanna Svitina, Ioannis Papantoniou   +3 more
wiley   +1 more source

Conformational Isomerization Involving Conserved Proline Residues Modulates Oligomerization of the NS1 Interferon Response Inhibitor from the Syncytial Respiratory Virus [PDF]

, 2019
Interferon response suppression by the respiratory syncytial virus relies on two unique nonstructural proteins, NS1 and NS2, that interact with cellular partners through high-order complexes.
Alonso, Leonardo Gabriel, Aran, Martin, Borkosky, Silvina Susana, Conci, Julieta, de Oliveira, Guilherme A. P., de Prat Gay, Gonzalo, Esperante, Sebastian, Mohana Borges, Ronaldo, Pagani, Talita Duarte, Álvarez Paggi, Damián Jorge   +9 more
core   +1 more source

Eutectozymes as Soft Hybrid Materials for Advanced Biocatalysis

Advanced Materials, EarlyView.
Eutectozymes are sustainable hybrid materials that embed a GOx–HRP cascade within hydrophobic eutectogels featuring a dual supramolecular–covalent network. This architecture preserves native enzyme structure and stability, enables efficient heterogeneous biocatalysis in aqueous media, and positions eutectogels as robust platforms for next‐generation ...
Manuel Eduardo Martinez Cartagena, Lucia Suarez, Aitor Ontoria, Francisca J. Benitez, Elixabete Rezabal, María Soledad Orellano, Marcelo Calderón, Cristián Huck‐Iriart, Agustin S. Picco, Matias L. Picchio, Ana Beloqui   +10 more
wiley   +1 more source

Thermal analysis of osmotically dehydrated fish meat [PDF]

Journal on Processing and Energy in Agriculture, 2015
Thermal analysis of osmotically treated fish (Carassius gibelio) meat was performed by three thermal techniques: Differential Scanning Calorimetry (DSC) Modulated Differential Scanning Calorimetry (MDSC) and Thermogravimetry (TGA).
Ostojić Sanja, Micić Darko, Zlatanović Snežana, Kovačević Olgica, Pezo Lato, Simonović Branislav R., Lević Ljubinko   +6 more
doaj  

Equation to Line the Borders of the Folding–Unfolding Transition Diagram of Lysozyme [PDF]

, 2016
It is important for the formulators of biopharmaceuticals to predict the folding-unfolding transition of proteins. This enables them to process proteins under predetermined conditions, without denaturation.
Forbes, Robert Thomas, Grimsey, Ian M., Mohammad, Mohammad Amin   +2 more
core   +1 more source

Assembling a True “Olympic Gel” From over 16 000 Combinatorial DNA Rings

Advanced Materials, EarlyView.
Olympic gels are an elusive class of soft matter, consisting of molecular networks held together purely by mechanically interlocked rings. Their topological structure promises unique properties and functions, but their synthesis has proven notoriously difficult.
Sarah K. Speed, Yu‐Hsuan Peng, Azra Atabay, Krishna Gupta, Toni Müller, Carolin Fischer, Ilka M. Hermes, Jens‐Uwe Sommer, Michael Lang, Elisha Krieg   +9 more
wiley   +1 more source

Hierarchically Engineered Multi‐Enzyme Nanoreactors for in vitro Drug Biosynthesis and Pathway Transplantation Into Cells

Advanced Materials, EarlyView.
A hierarchically structured metal–organic framework (eMIL) is shown to host the complete six‐enzyme biosynthesis pathway for the anti‐cancer pigment violacein, reshaping reaction dynamics and multiplying in vitro yields. eMIL nanoreactors deliver this reconstituted bacterial multi‐protein system into mammalian cells, where cell‐derived substrates and ...
Ainur Sharip, Somayah S. Qutub, Manar M. Farooqui, Walaa Baslyman, Nida Khalfay, Lukman O. Alimi, Patricia Lopez Sanchez, Lingyun Zhao, Milena Chernyshevskaia, Giovanni Colombo, Niveen M. Khashab, Stefan T. Arold, Raik Grünberg   +12 more
wiley   +1 more source