Results 91 to 100 of about 39,830 (289)

Drug‐Induced Cuproptosis Defines the Therapeutic Window of Celecoxib in Intervertebral Disc Degeneration via the HSP90‐RBX1 Axis

Advanced Science, EarlyView.
This study reveals the dual role of celecoxib in intervertebral disc degeneration. While low concentrations are protective, high concentrations induce toxicity by upregulating HSP90, which synergizes with USP15 to deubiquitinate and stabilize RBX1. This leads to degradation of COMMD1/ATP7B, copper dyshomeostasis, and ultimately, cuproptosis.
Youfeng Guo, Hongju Xiao, Shenghao Ba, Yu Zhou, Bijun Wang, Bin Yu, Yufeng Huang, Haihong Zhao, Zhefan Stephen Chen, Na Shen, Zhaoyu Ba, Desheng Wu   +11 more
wiley   +1 more source

Screening for mutations in human alpha-globin genes by nonradioactive single-strand conformation polymorphism

Brazilian Journal of Medical and Biological Research, 2003
Point mutations and small insertions or deletions in the human alpha-globin genes may produce alpha-chain structural variants and alpha-thalassemia.
S.B. Jorge, M.B. Melo, F.F. Costa, M.F. Sonati   +3 more
doaj   +1 more source

Assessment of Bacterial Diversity of Industrial Poultry Wastewater by Denaturing Gradient Gel Electrophoresis (DGGE) and the Cultivation Method in Order to Inform Its Reuse in Agriculture. [PDF]

Biomed Res Int, 2022
Oueslati A, Hassen W, Ellafi A, Alibi S, Jaziri A, Bachkouel S, Oueslati I, Snoussi M, Adnan M, Patel M, Elasbali AM, Mansour HB.   +11 more
europepmc   +1 more source

Phylogenetic sequence affiliation of amplified 16S rRNA gene sequences excised from archaeal denaturing gradient gel electrophoresis (DGGE) gels.

, 2014
Phylogenetic sequence affiliation of amplified 16S rRNA gene sequences excised from archaeal denaturing gradient gel electrophoresis (DGGE) gels.
Qing Wu (277441), Liping Hao (362213), Liming Shao (541157), Pinjing He (541158), Fan Lü (3917735)   +4 more
core   +1 more source

Spatiotemporal Control of Formation of Dynamic Protein Fiber Assemblies via Photophysical Effects of a Focused Laser Beam

Advanced Science, EarlyView.
Tightly focused laser irradiation can accumulate tubulin proteins at/around the laser focus, which leads to the formation of highly ordered microtubule assemblies. The assemblies can exhibit various dynamic behaviors such as radial motion, bundling, and flagella‐like rotation with motor protein and chemical energy, highlighting as a unique tool for ...
Hiroshi Y. Yoshikawa, Ren Shirata, Takuya Takeshige, Riki Yoshida, Fumika Kiryu, Kei Takano, Shuma Matsumoto, Reiji Kawanami, Natsumi Sawada, Chi‐Shiun Wu, Yang‐Hsin Shih, Hiromasa Niinomi, Takahisa Matsuzaki, Seiichiro Nakabayashi, Tomoaki Matsuura, Teruki Sugiyama, Ryuzo Kawamura   +16 more
wiley   +1 more source

Identification of yeasts by polymerase-chain-reaction-mediated denaturing gradient gel electrophoresis in marcha, an ethnic amylolytic starter of India

Journal of Ethnic Foods, 2016
Background: Marcha is an ethnic amylolytic starter that is used to ferment boiled cereals to produce alcoholic drinks, commonly called jaanr, in the Himalayan Regions of Sikkim and Darjeeling of India.
Shankar P. Sha, Anu Anupama, Pooja Pradhan, Gandham S. Prasad, Jyoti P. Tamang   +4 more
doaj   +1 more source

The RNA‐Binding Protein PARN Remodeled 3′ UTR Structure Defines Poly(A)‐Loading Sites to Mediate Immunoglobulin Homeostasis

Advanced Science, EarlyView.
ABSTRACT Class Switch Recombination (CSR) is essential for generating high‐affinity antibody isotypes from IgM during adaptive humoral responses. Despite well‐established roles for various transcription factors, whether CSR is subject to dedicated post‐transcriptional control represents a significant gap in knowledge.
Siyuan Sun, Chen Yang, Xiaoyu Wang, Naijing Hu, Shengyao Zhang, Xinchun Li, Yu Chen, Jianan Zhai, Xiangfeng Tang, Wei Lu, Chenxu Lu, Changchang Cao, Weiru Yu, Wenhao Wu, Xiaonan Nie, Fengchao Wang, Bing Fang, Fazheng Ren, Yixuan Li, Juan Chen   +19 more
wiley   +1 more source

Effects of bleaching wastewater irrigation on soil quality of constructed reed wetlands

Chemical Speciation & Bioavailability, 2016
Constructed reed wetland microcosms (CRWs) in a lab of east China have been irrigated with bleaching wastewater per month for a reed growth season. The soil physicochemical properties, enzyme activities (i.e.
Cheng Ding, Wenjun Yang, Aihui Chen, Liqiang Cui, Zhaoxia Li   +4 more
doaj   +1 more source

Denaturing gradient gel electrophoresis and multi-SIR profiles of soil microbial communities from a karst doline at Aggtelek National Park, Hungary. [PDF]

Folia Microbiol (Praha), 2021
Mucsi M, Krett G, Szili-Kovács T, Móga J, Borsodi AK.   +4 more
europepmc   +1 more source

Identification of the Bacterial Community Responsible for Decontaminating Eleme Petrochemical Industrial Effluent Using 16s RDNA PCR Denaturing Gradient Gel Electrophoresis

, 2014
Identification of bacteria community responsible for decontaminating Eleme petrochemical industrial effluent using 16S PCR denaturing gradient gel electrophoresis (DGGE) was determined.
Atuanya, EI, Ajuzie, CU
core   +1 more source