Results 71 to 80 of about 39,830 (289)

p53 Mutations and DNA Ploidy in Colorectal Adenocarcinomas

Analytical Cellular Pathology, 1998
The p53 tumour suppressor gene has an important role in the the maintenance of genome stability and its mutational inactivation may be at the origin of aneuploidy in cancer cells.
Paola Campomenosi, Paola Assereto, Massimo Bogliolo, Gilberto Fronza, Angelo Abbondandolo, Antonella Capasso, Patrizia F. Bellomo, Roberto Monaco, Anna Rapallo, Andrea Sciutto, Roberto Orecchia, Elio Geido, Walter Giaretti   +12 more
doaj   +1 more source

Autogenic versus environmental control during development of river biofilm [PDF]

, 2009
In the natural environment, microbial community structure of river biofilm is controlled by biotic and abiotic factors. This study explored the capacity to manipulate the structure of microbial communities by modifying environmental conditions during the
Émilie Lyautey, Paule, Armelle, Armelle Paule, Frédéric Garabetian, Rols, Jean-Luc, Lyautey, Emilie, Garabétian, Frédéric, Jean-Luc Rols   +7 more
core   +1 more source

β‐Elemene Rescues Radiation‐Induced Enteritis by Orchestrating a Host‐Microbiome Circuit That Fuels Epigenetic DNA Repair

Advanced Science, EarlyView.
This study elucidates that β‐elemene promotes cellular uptake of L. gasseri‐derived lactate by enhancing the membrane translocation of MCT1 in a CD147‐dependent manner. Intracellular lactate, through the lactylation of RBBP4 at the K26 site, recruits EP300 to the promoter regions of downstream genes (POLD1/POLD3), catalyzing H3K27ac modification.
Jiancheng He, Jiapeng Bao, Shukang Deng, Weijie Zang, Haoming Yan, Zihao Zhao, Guangze Zhang, Ruiqing Liu, Junjie Chen, Yilin Hu, Wanjiang Xue   +10 more
wiley   +1 more source

Microbiological analysis and microbiota in oyster: a review [PDF]

Invertebrate Survival Journal, 2016
Oyster, is a popular shellfish consumed globally. As a bivalve filter-feeding invertebrate mollusk, oyster harbors many microorganisms, which could eventually cause potential health risks of human.
H Chen, Z Liu, Y Shi, H H Ding
doaj   +1 more source

Nucleic acid contamination of glycogen used in nucleic acid precipitation and assessment of linear polyacrylamide as an alternative co-precipitant

BioTechniques, 2009
Molecular-grade glycogen is widely used to recover nanogram or picogram quantities of DNA and RNA across molecular biology applications in the life sciences. As a result, its purity is critical to obtain reliable results.
Andrea K. Bartram, Calvin Poon, Josh D. Neufeld   +2 more
doaj   +1 more source

Denaturing Gradient Gel Electrophoresis Analysis of Archaeal and Bacterial Populations in a Submerged Anaerobic Membrane Bioreactor Treating Landfill Leachate at Low Temperatures

, 2012
This study investigated the evolution of archaeal and bacterial populations of two submerged anaerobic membrane bioreactors (SAMBRs) operating at a mean solids residence time of 30 (SAMBR30) and 300 days (SAMBR300) at mesophilic and psychrophilic ...
David C. Stuckey, Trzcinski, Antoine P., Antoine P. Trzcinski, Stuckey, David C.   +3 more
core   +1 more source

S100A14 in Tumor‐Derived EVs Targets PIAS3 to Reprogram Astrocytes and Induce Immunosuppressive Microenvironment Promoting Brain Metastasis and Germacrone Reversal Effect

Advanced Science, EarlyView.
This study identifies S100A14 in tumor‐derived exosomes as a key driver of brain metastasis. S100A14 targets PIAS3 in astrocytes, activating STAT3 signaling and promoting immunosuppressive MDSCs recruitment via chemokine secretion. Germacrone, a natural compound, binds S100A14 to disrupt this axis, effectively inhibiting brain metastasis with low ...
Qian Feng, Xia Yang, Lin An, Xue‐Yu Wang, Ming‐Rui Wang, Zhuo‐Hong Cai, Cai‐Jun Xie, Li‐Jun Qiao, You‐Bi Shen, Xi‐Min Liang, Rong Zhang, Cai‐Yan Wang, Zhong‐Qiu Liu, Rong‐Rong Zhang   +13 more
wiley   +1 more source

Bacterial community survey of sediments at Naracoorte Caves, Australia

International Journal of Speleology, 2012
Bacterial diversity in sediments at UNESCO World Heritage listed Naracoorte Caves was surveyed as part of an investigation carried out in a larger study on assessing microbial communities in caves. Cave selection was based on tourist accessibility; Stick
Ball Andrew S., Kirby Greg, Bourne Steven, Cao Xiangsheng, Mazaheri Nezhad Fard Ramin, Adetutu Eric M., Shahsavari Esamaeil, Thorpe Krystal   +7 more
doaj  

Astrocytic Phenotypic Switching in Posterior Piriform Cortex Orchestrates Bone Cancer Pain–Depression Comorbidity via Purinergic–Noradrenergic Signaling

Advanced Science, EarlyView.
Bone cancer pain and depression share a common origin: astrocytic A2‐to‐A1 transition in the posterior piriform cortex. This phenotypic shift disrupts the ATP–adenosine–A2AR–norepinephrine axis, simultaneously driving nociceptive and affective dysfunction.
Jiang‐Ping Liu, Jun‐Han Zhang, Zhi‐Xuan Tan, Wei‐Bing Yan, Ya‐Ru Yuan, Yao Liu, Bing‐Di Wei, Meng‐Qi Ding, Zhuo‐Min Fu, Ying Liu, An‐Qi Wang, Lin Ma, Yong‐Hong Li, Er‐Qing Chai, Chao‐Jun Wei   +14 more
wiley   +1 more source

Bacterial community structure of mangrove sediments in relation to environmental variables accessed by 16S rRNA gene-denaturing gradient gel electrophoresis fingerprinting

Scientia Marina, 2009
Bacterial community structure and the relationship between environmental variables and microbial communities in the surface sediments of tropical mangrove ecosystems were investigated in Sanya, Hainan Island, China. Profiles of bacterial communities were
Yanying Zhang, Junde Dong, Bin Yang, Juan Ling, Youshao Wang, Si Zhang   +5 more
doaj   +1 more source