Results 81 to 90 of about 1,234,769 (254)

Sub-Lethal Effects of Pesticides on the DNA of Soil Organisms as Early Ecotoxicological Biomarkers

Frontiers in Microbiology, 2020
This review describes the researches performed in the last years to assess the impact of pesticide sub-lethal doses on soil microorganisms and non-target organisms in agricultural soil ecosystems.
Costantino Vischetti, Cristiano Casucci, Arianna De Bernardi, Elga Monaci, Luca Tiano, Fabio Marcheggiani, Maurizio Ciani, Francesca Comitini, Enrica Marini, Eren Taskin, Edoardo Puglisi   +10 more
doaj   +1 more source

The GPX3‐VCAM1 Axis Gates Pro‐Fibrotic Tubule Cell Fate in Hyperuricemic Nephropathy

Advanced Science, EarlyView.
Hyperuricemia induces NLRP3 inflammasome signaling activation and downregulation of GPX3 in proximal tubular epithelial cells, leading to oxidative stress–driven VCAM1 upregulation, emergence of pro‐fibrotic proximal tubule cells, macrophage recruitment, and renal fibrosis.
Yunfei Qi, Qiang Zhao, Yue Lve, Yaming Yuan, Tingting Zhou, Yue Yuan, Dexi Wu, Yifan Tang, Yan Liu, Zhigang Li, Chunping Jiang, Qiurong Ding   +11 more
wiley   +1 more source

Detection of Human DNA Polymorphisms with a Simplified Denaturing Gradient Gel Electrophoresis Technique. [PDF]

, 1987
Single base pair differences between otherwise identical DNA molecules can result in altered melting behavior detectable by denaturing gradient gel electrophoresis.
Noll, Walter W, Collins, Mary
core  

Mutation detection in the alpha-1 antitrypsin gene (PI) using denaturing gradient gel electrophoresis

, 2001
A method for mutation detection in the alpha-1 antitrypsin gene (protease inhibitor 1; PI) has been developed using denaturing gradient gel electrophoresis of PCR amplified gene fragments.
Lodewyckx, L, VANDERVORST, Carine, MICHIELS, Luc, VANDEVYVER, Caroline, Van Steenbergen, W, RAUS, Jef   +5 more
core   +1 more source

Helicobacter pylori‐Induced Persistent IGF2BP1 Activation Promotes Ferroptosis Resistance in Gastric Tumorigenesis

Advanced Science, EarlyView.
Helicobacter pylori infection induces sustained upregulation of the RNA‐binding protein IGF2BP1 in gastric epithelial cells, establishing a persistent epitranscriptomic program. IGF2BP1 stabilizes SLC7A11 mRNA in an m6A‐dependent manner to suppress ferroptosis and promote epithelial survival under oxidative stress. Pharmacological inhibition of IGF2BP1
Jing Ning, Xin Guan, Xinyu Hao, Jing Zhang, Deyao Li, Ying Xiong, Wenlin Zhang, Xiurui Han, Yanfei Lang, Meiling Zhou, Mengjie Yang, Zhi Huang, Tinghui Qu, Ming Zu, Qiao Meng, Weiwei Fu, Fengmin Lu, Jing Zhang, Xiangmei Chen, Tong Liu, Shigang Ding   +20 more
wiley   +1 more source

Community analysis and recovery of phenol-degrading bacteria from drinking water biofilters

Frontiers in Microbiology, 2016
Phenol is a ubiquitous organic contaminant in drinking water. Biodegradation plays an important role in the elimination of phenol pollution in the environment, but the information about phenol removal by drinking water biofilters is still lacking. Herein,
Qihui eGu, Qingping eWu, Jumei eZhang, Weipeng eGuo, Huiqing eWu, Ming eSun   +5 more
doaj   +1 more source

Denaturing Gradient Gel Electrophoresis Analysis of Archaeal and Bacterial Populations in a Submerged Anaerobic Membrane Bioreactor Treating Landfill Leachate at Low Temperatures

, 2012
This study investigated the evolution of archaeal and bacterial populations of two submerged anaerobic membrane bioreactors (SAMBRs) operating at a mean solids residence time of 30 (SAMBR30) and 300 days (SAMBR300) at mesophilic and psychrophilic ...
David C. Stuckey, Trzcinski, Antoine P., Antoine P. Trzcinski, Stuckey, David C.   +3 more
core   +1 more source

Autogenic versus environmental control during development of river biofilm [PDF]

, 2009
In the natural environment, microbial community structure of river biofilm is controlled by biotic and abiotic factors. This study explored the capacity to manipulate the structure of microbial communities by modifying environmental conditions during the
Émilie Lyautey, Paule, Armelle, Armelle Paule, Frédéric Garabetian, Rols, Jean-Luc, Lyautey, Emilie, Garabétian, Frédéric, Jean-Luc Rols   +7 more
core   +1 more source

A Comprehensive In Vitro Approach for Assessing the Physiological Degradation of Medical Implants: The Silkothane Arteriovenous Graft Case Study

Advanced NanoBiomed Research, EarlyView.
Evaluating the degradation of absorbable medical devices in vitro demands physiologically relevant conditions. This study presents a comprehensive framework applied to a three‐layered silk fibroin/polyurethane arteriovenous graft, employing human enzymes at physiological concentrations over 6 months. Multiparametric analyses of both graft structure and
Cristina Oldani, Alice Caldiroli, Federica Barzaghi, Nina Bono, Gabriele Candiani, Stefania Adele Riboldi   +5 more
wiley   +1 more source

Screening for mutations in human alpha-globin genes by nonradioactive single-strand conformation polymorphism

Brazilian Journal of Medical and Biological Research, 2003
Point mutations and small insertions or deletions in the human alpha-globin genes may produce alpha-chain structural variants and alpha-thalassemia.
S.B. Jorge, M.B. Melo, F.F. Costa, M.F. Sonati   +3 more
doaj   +1 more source