Results 71 to 80 of about 85,577 (346)

Toxicity of Hexyl Acrylate Modified PAMAM Dendrimer [PDF]

Trends in Pharmaceutical Sciences, 2018
The aim of this study was to evaluate the effect of the hexyl acrylate conjugated polyamidoamine (PAMSM) dendrimer on different cell lines in the presence and absence of serum.
Mohammad Ashkan Naderian, Amin Reza Akbarizadeh, Akram Jamshidzadeh, Ali Dehshahri   +3 more
doaj  

Evaluation of the Dual Impact of Nanotechnologies on Health and Environment Through Alternative Bridging Models

Advanced Healthcare Materials, EarlyView.
This review explores how alternative invertebrate and small‐vertebrate models advance the evaluation of nanomaterials across medicine and environmental science. By bridging cellular and organismal levels, these models enable integrated assessment of toxicity, biodistribution, and therapeutic performance.
Marie Celine Lefevre, Margherita Bernardeschi, Matteo Battaglini, Gianni Ciofani   +3 more
wiley   +1 more source

Novel water soluble dendrimer nanocarrier for enhanced photodynamic efficacy of protoporphyrin Ⅸ

Nano Biomedicine and Engineering, 2012
The present study describes the development and evaluation of a novel biocompatible dendrimer-based nano drug delivery system which is readily soluble in water prepared by condensing Phloroglucinol and Succinic Acid (PGSA) and could efficiently ...
Murugesan Suresh Kumar, Anish Babu, Ramachandran Murugesan, Kadarkaraithangam Jeyasubramanian   +3 more
doaj   +1 more source

Intrinsically Disordered Protein‐Inspired Nanovector‐Based Coacervates for the Direct Cytosolic Transport of Biomacromolecules

Advanced Materials, EarlyView.
Intrinsically disordered protein‐inspired nanovectors (IDP‐NVs) form stable nanocoacervates (NCs) with diverse biomacromolecules. In situ conformational changes confer stability and adaptability to NCs under dynamically changing physiological conditions.
Soyeong Jin, Hyemin Park, Seuk‐Min Ryu, Dagyeong Guk, Jaeeun Lee, Seongeon Jin, Changjoon Keum, Jinyoung Park, Myoung‐Hwan Park, Chaekyu Kim, Hojun Kim, Jaegeun Noh, Kwan Hyi Lee, Ja‐Hyoung Ryu, Youngdo Jeong   +14 more
wiley   +1 more source

Comparison of generation 3 polyamidoamine dendrimer and generation 4 polypropylenimine dendrimer on drug loading, complex structure, release behavior, and cytotoxicity

International Journal of Nanomedicine, 2011
Naimin Shao1, Yunzhang Su1, Jingjing Hu2, Jiahai Zhang3, Hongfeng Zhang1, Yiyun Cheng1,41School of Life Sciences, East China Normal University, Shanghai, 2CAS Key Laboratory of Soft Matter Chemistry, Department of Chemistry, University of Science and ...
Shao N, Su Y, Hu J, Zhang J, Zhang H, Cheng Y   +5 more
doaj  

Structure of DNA-Functionalized Dendrimer Nanoparticles

, 2012
Atomistic molecular dynamics simulations have been carried out to reveal the characteristic features of ethylenediamine (EDA) cored protonated poly amido amine (PAMAM) dendrimers of generation 3 (G3) and 4 (G4) that are functionalized with single ...
Aldaye, Alivisatos, Bao, Berendsen, Blab, Bliznyuk, Carbone, Choi, Choi, Condon, Dai, Dai, Duan, Esfand, Feldkamp, Gurtovenko, Hainfeld, Hill, Hsu, Huang, Hurst, Jain, Jain, Jorgensen, Kalogianni, Karatasos, Ke, Klos, Lara, Largo, Lee, Lee, Lee, Lee, Li, Liu, Lu, Lyulin, Macfarlane, Maiti, Maiti, Maiti, Maiti, Maiti, Mattaparthi Venkata Satish Kumar, Mayo, Mijovic, Mirkin, Mizutani, Nandy, Niemeyer, Niemeyer, Nykypanchuk, Paciotti, Padovan-Merhar, Park, Park, Pearlman, Prabal K Maiti, Rosi, Rosi, Ryckaert, Seeman, Sosinsky, Starr, Stechemesser, Storhoff, Suek, Sun, Thankappan, Tomalia, Tomalia, Tomalia, Tomalia, Tomalia, Uppuluri, Vasumathi, Xiong, Zhao   +78 more
core   +1 more source

A Formalism for Scattering of Complex Composite Structures. 1 Applications to Branched Structures of Asymmetric Sub-Units [PDF]

, 2012
We present a formalism for the scattering of an arbitrary linear or acyclic branched structure build by joining mutually non-interacting arbitrary functional sub-units.
Carsten Svaneborg, de Gennes P. G., Freed K. F., Guinier A., Guinier A., Hansen J.-P., Higgins J. S., Itzykson G., Jan Skov Pedersen, Lindner P.   +9 more
core   +2 more sources

Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy

Advanced Materials, EarlyView.
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa, Gracia Mendoza, Silvia Irusta, Manuel Arruebo   +3 more
wiley   +1 more source

An Anti-Inflammatory Poly(PhosphorHydrazone) Dendrimer Capped with AzaBisPhosphonate Groups to Treat Psoriasis

Biomolecules, 2020
Dendrimers are nanosized, arborescent macromolecules synthesized in a stepwise fashion with attractive degrees of functionality and structure definition. This is one of the reasons why they are widely used for biomedical applications. Previously, we have
Ranime Jebbawi, Abdelouahd Oukhrib, Emily Clement, Muriel Blanzat, Cédric-Olivier Turrin, Anne-Marie Caminade, Eric Lacoste, Séverine Fruchon, Rémy Poupot   +8 more
doaj   +1 more source

Spatial segregation of mixed-sized counterions in dendritic polyelectrolytes

Scientific Reports, 2021
Langevin dynamics simulations are utilized to study the structure of a dendritic polyelectrolyte embedded in two component mixtures comprised of conventional (small) and bulky counterions.
J. S. Kłos, J. Paturej
doaj   +1 more source