Results 161 to 170 of about 200,382 (281)

Ferritin‐Doped Nanoparticles Triggered Tumor‐Specific Darkening for Enhanced Photothermal Tumor Ablation and Immune Activation

Advanced Healthcare Materials, EarlyView.
Ferritin‐doped hybrid nanoparticles triggered accurate tumor‐specific hemorrhage for enhanced in situ photothermal therapy and evoked anti‐tumor immunity. Notably, HFn/GA‐Fe specifically induced tumor hemorrhage 12 h after intravenous injection, resulting in visible color darkening. Through photoacoustic imaging, tumor vessels could be clearly observed
Haidong Zha, Xiao Liang, Long Xi, Jiamao Chen, Wenzhao Zhong, Zhen Yuan, Meng Xu, Ying Zheng   +7 more
wiley   +1 more source

Deep learning-based segmentation and density estimation of corneal nerves and dendritic cells from In Vivo confocal microscopy images. [PDF]

Sci Rep
Ji M, Song Y, Roth J, Dashti A, Lazo J, Lincke A, Macedo AFT, Löwe W, Lagali N.   +8 more
europepmc   +1 more source

From RNA to DNA: How Cargo Identity Reprograms Lipid Nanoparticle Architecture and Function

Advanced Healthcare Materials, EarlyView.
The evolution of lipid nanoparticles (LNPs) spans from RNA‐LNPs, used in mRNA vaccines, to DNA‐LNPs, ideal for gene therapies. Emerging bionano architectures, decorated with DNA and plasma proteins, pave the way for advanced DNA‐based therapies that are more stable, targeted, and customizable.
Erica Quagliarini, Daniela Pozzi, Giulio Caracciolo   +2 more
wiley   +1 more source

Investigation of synaptic connectivity in functional in vitro neuronal assemblies. [PDF]

Cell Rep Methods
Zaccaria C, Malkoç A, Auslender I, Heydari Y, Canossa M, Vignoli B, Pavesi L.   +6 more
europepmc   +1 more source

Bioengineered 3D hPSC‐Cholangiocyte Ducts With Physiological Signals for Biliary Disease Modeling

Advanced Healthcare Materials, EarlyView.
Tian and colleagues generated a bioengineered bile duct from human pluripotent stem cell (hPSC)‐derived intrahepatic cholangiocytes within a high‐throughput, 384‐well platform to systematically examine the influence of biliary physiological signals including fluid flow, stromal cells and bile acids, and models intrahepatic biliary disease progression ...
Britney Tian, Mina Ogawa, Manami Kondo, Gabrielle Langeveld, Ling Jun Huan, Feng Zhang, Andrew Hollinger, Sara Deir, Christine Bear, Boyang Zhang, Shinichiro Ogawa   +10 more
wiley   +1 more source

Neuropsin-expressing cells in the retina affect melanopsin expression and response to light in mice. [PDF]

Sci Rep
Calligaro H, Khov B, Kim KY, Le H, Ellisman M, Panda S.   +5 more
europepmc   +1 more source

Injectable Stimuli‐Responsive Amphiphilic Hydrogel for Rapid Hemostasis, Robust Tissue Adhesion, and Controlled Drug Delivery in Trauma and Surgical Care

Advanced Healthcare Materials, EarlyView.
Fast‐acting hydrogel seals bleeding wounds as the illustrated injectable, pH‐responsive network rapidly gels in situ to stop hemorrhage, adhere strongly to wet tissue, and release antibiotics in a controlled, pH‐dependent manner. The material withstands high pressures, shows excellent biocompatibility, and degrades safely, offering a versatile platform
Arvind K. Singh Chandel, Runali Patil, Abrar Ali Khan, Deeksha Pandit, Kaushik Chatterjee, Maurice N. Collins   +5 more
wiley   +1 more source

Circular RNA <i>circHomer1</i> mediates hippocampal functions via ribonucleoprotein granule transport and dendritic targeting of synaptic RNAs. [PDF]

Sci Adv
Cai Y, Zheng Z, Xu H, Zhu Y, Zepeda JC, Grueter BA, Wang X, Ku T, Duan Y, Tsang HWS, Fu WY, Fu AKY, Mellios N, Wong HH, Lai KO, Ip JPK.   +15 more
europepmc   +1 more source

An In Situ Embedded B‐MOF Sponge With Shape‐Memory for All‐in‐One Diabetic Wound Therapy

Advanced Healthcare Materials, EarlyView.
A smart shape‐memory sponge dressing (P1A3@B‐MOF) is developed for accelerated diabetic wound healing. It achieves pH‐responsive corelease of Zn2+ and salvianolic acid B, synergistically providing antibacterial action, repolarizing macrophages to the M2 phenotype, and promoting angiogenesis.
Hai Zhou, Chaoyang Huang, Yanqi Chen, Tingzi Zhao, Fengyi Zhu, Gong Jun, Jinrong Zhang, Yingsong Pan, Qiulan Wen, Lei Yang, Huihui Zhang, Lianglong Chen   +11 more
wiley   +1 more source

Sex differences in neurobehavior and the adult hippocampal neurogenic niche: influence of traumatic brain injury and CLIP antagonism. [PDF]

Front Behav Neurosci
Iannucci J, Venkatasamy L, Davis M, Nguyen TA, Yadav GS, Nugeness V, Dominy R, Arisi GM, Newell-Rogers MK, Shapiro LA.   +9 more
europepmc   +1 more source