Results 261 to 270 of about 804,900 (360)

Engineering Cortical Networks: An Open Platform for Controlled Human Circuit Formation and Synaptic Analysis In Vitro

Advanced Healthcare Materials, EarlyView.
An advanced on‐chip cortical network platform merges human stem cell‐derived neurons with microfabricated devices, enabling precise large‐format circuit design, optogenetic control, and molecular dissection of synaptic formation. This innovative system offers a powerful new tool to explore and model brain connectivity, disease mechanisms, can serve as ...
Pacharaporn Suklai, Taylor Minckley, Cathleen Hagemann, Karolina Faber, Rosalind Norkett, Ludovica Guetta, Kelly O'Toole, Bethany Geary, Michael J. Devine, Andrea Serio   +9 more
wiley   +1 more source

Distinct microbiota composition and dendritic cell activation in the appendix microenvironment of ulcerative colitis patients. [PDF]

Gut Microbes
Scarpa M, Castagliuolo I, Patuzzi I, Kotsafti A, Stepanyan A, Armellin C, Tagliente G, Savarino E, Zingone F, Ruffolo C, Saadeh L, Spolverato G, Angriman I, Scarpa M.   +13 more
europepmc   +1 more source

Dendritic Cells: Unique Leukocyte Populations Which Control the Primary Immune Response

, 1997
Derek N.J. Hart
openalex   +1 more source

Vibration‐Mediated Recovery of Irradiated Osteocytes and Their Regulatory Role in Breast Cancer Bone Metastasis

Advanced Healthcare Materials, EarlyView.
Radiotherapy damages bone and disrupts osteocyte function, yet mechanically mediated protection remains largely unexplored. This study demonstrates that low‐magnitude, high‐frequency (LMHF) vibration mitigates irradiated osteocyte apoptosis, restores their ability to regulate breast cancer extravasation, and acts synergistically with radiotherapy to ...
Xin Song, Kimberly Seaman, Amel Sassi, Chun‐Yu Lin, Tiankuo Chu, Liyun Wang, Yu Sun, Lidan You   +7 more
wiley   +1 more source

Corrigendum to SLAMF7 and SLAMF8 receptors shape human plasmacytoid dendritic cell responses to intracellular bacteria. [PDF]

J Clin Invest
Pellegrini JM, Keriel A, Gorvel L, Hanniffy S, Arce-Gorvel V, Bosilkovski M, Solera J, Méresse S, Mémet S, Gorvel JP.   +9 more
europepmc   +1 more source

Multiscale Profiling of Nanoscale Metal‐Organic Framework Biocompatibility and Immune Interactions

Advanced Healthcare Materials, EarlyView.
A multi‐scale, hierarchical ‘Safety‐by‐Design’ pipeline combining machine learning, ex vivo human blood assays, and in vivo models enables the systematic immunotoxicity and biocompatibility profiling of nanoscale metal‐organic frameworks, accelerating their safe clinical translation. Abstract The clinical translation of metal‐organic frameworks (MOFs) –
Yunhui Zhuang, Bárbara B. Mendes, Dhruv Menon, Jhenifer Oliveira, Xu Chen, Fatma Demir Duman, João Conniot, Sergio Mercado, Xiewen Liu, Shi‐Yuan Zhang, João Conde, Rachel E. Hewitt, David Fairen‐Jimenez   +12 more
wiley   +1 more source

Galectin-9 regulates dendritic cell polarity and uropod contraction by modulating RhoA activity. [PDF]

J Cell Biol
Franken GA, Warner H, Cuenca-Escalona J, Stehle IF, van Reijmersdal VPA, Klomp SE, Schreurs K, Rodgers-Furones A, Gokhale RR, Vullings M, Classens R, Di Blasio S, Dolen Y, van Deventer S, Wolf K, Wortel IMN, Hetmanski JHR, van Spriel AB, Querol Cano L.   +18 more
europepmc   +1 more source

Inhalability and Bioactivity of Spray‐Dried versus Pressurized Gas eXpanded Liquid Technology‐Processed Yeast Beta‐Glucan Microparticles for Anti‐Fibrotic Therapies

Advanced Healthcare Materials, EarlyView.
PGXTEC) liquid technology is utilized to develop highly respirable yeast beta‐glucan (YBG) microparticles for the treatment of pulmonary fibrosis. Compared to conventionally processed spray‐dried YBG, PGXTEC‐YBG exhibits greatly improved aerodynamic properties, enhanced pro‐fibrotic macrophage uptake, and effective downregulation of pro‐fibrotic ...
Nate Dowdall, Safaa Naiel, Quan Zhou, Pareesa Ali, Tamana Rubina Yousof, Emily Wong, Ricardo Couto, Byron Yépez, Bernhard Seifried, Paul Moquin, Rod Rhem, Myrna Dolovich, Martin Rainer Kolb, Kjetil Ask, Todd Hoare   +14 more
wiley   +1 more source

Advanced Nanoparticle Therapeutics for Targeting Neutrophils in Inflammatory Diseases

Advanced Healthcare Materials, EarlyView.
This review highlights recent advances in nanoparticle‐based strategies to modulate neutrophil activity in inflammatory diseases. By targeting inflammatory neutrophils, NET formation, and neutrophil apoptosis or recruitment, these approaches aim to improve therapeutic precision.
Min Ji Byun, Elizabeth S. Nakasone, Ha Eun Shin, Hyojin Lee, Jong‐Chan Park, Wonhwa Lee, Wooram Park, Chun Gwon Park, Juwon Park, Se‐Na Kim   +9 more
wiley   +1 more source

Histone methyltransferase DOT1L differentially affects the development of dendritic cell subsets

Bouma RG, de Leeuw W, Wang AZ, Malik M, Stolwijk JG, Konijn VA, Mensink A, Proost N, Nijen Twilhaar MK, van Welsem T, Seyed Toutounchi N, Affandi AJ, van Dinter JT, van Leeuwen F, den Haan JM.   +14 more
europepmc   +1 more source