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Dendritic cells

ANZ Journal of Surgery, 2002
Dendritic cells (DC) are the most effective or ‘professional’ of the antigen‐presenting cells (APC) that initiate primary immune responses. They are located at surveillance sites where they capture and process antigens. They then initiate and regulate T‐ and B‐cell responses by expressing lymphocyte costimulatory molecules, migrating to lymphoid organs
Veronica Yao   +2 more
openaire   +5 more sources

Dendritic cells in glomerulonephritis

Virchows Archiv B Cell Pathology Including Molecular Pathology, 1992
Renal biopsies (n = 45) from patients with various forms of glomerulonephritis (GN), comprising mesangial IgA-GN (n = 25), focal glomerular sclerosis (n = 13) and acute GN (n = 7), were examined by double staining immunocytochemistry (APAAP, streptavidin-peroxidase) using unconjugated monoclonal antibodies (Ab) against--(i) the CD1b antigen expressed ...
Snjezana Cuzic   +2 more
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Dendritic Cells

Current Opinion in Hematology, 1998
Dendritic cells are potent stimulators of immune responses against foreign antigens. Recent advances in this area include the delineation of distinct developmental pathways for different dendritic cell subsets; the emerging concept that one dendritic cell subset has regulatory functions that may contribute to induction of tolerance to self antigens ...
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Dendritic Cell Biology

2005
Dendritic cells (DCs) are a special type of leukocytes able to alert the immune system to the presence of infections. They play a central role in the initiation of both innate and adaptive immune responses. This particular DC feature is regulated by the activation of specific receptors at the cell surface called Toll-like receptors (TLRs) that bind a ...
GRANUCCI, FRANCESCA   +2 more
openaire   +3 more sources

Dendritic cells in asthma

Current Opinion in Immunology, 2013
The lungs are constantly exposed to antigens, most of which are non-pathogenic and do not require the induction of an immune response. Dendritic cells (DCs) are situated at the basolateral site of the lungs and continuously scan the environment to detect the presence of pathogens and subsequently initiate an immune response.
Mary J. van Helden   +2 more
openaire   +4 more sources

Follicular Dendritic Cells and Dendritic Cell Nomenclature

1993
In the 10 years since the last nomenclature committee on dendritic cells met (Tew, Thorbecke and Steinman, J. Reticuloendothelial Society 31:371, 1982), considerable evidence has accumulated supporting the concept that Langerhans cells, interdigitating cells, and veiled cells are the same cell in different stages of maturation. It also appears that the
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Dendritic Cell Vaccines

2012
Despite progress in brain tumor therapy, the prognosis of malignant glioma patients remains dismal. Among the new treatments currently being investigated, immunotherapy is theoretically very attractive since it offers the potential for high tumor-specific cytotoxicity.
Yamanaka, Ryuya, Kajiwara, Koji
openaire   +3 more sources

Dendritic cell subsets

Seminars in Cell & Developmental Biology, 2018
Dendritic cells (DC) are professional antigen presenting cells comprising a variety of subsets, as either resident or migrating cells, in lymphoid and non-lymphoid organs. In the steady state DC continually process and present antigens on MHCI and MHCII, processes that are highly upregulated upon activation.
Timothy Patton   +3 more
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Pulmonary Dendritic Cells

American Journal of Respiratory and Critical Care Medicine, 2005
Dendritic cells (DCs) are leukocytes that are emerging as chief orchestrators of immune responses. The crucial task of DCs is the continuous surveillance of antigen-exposed sites throughout the body, and their unique responsibility is to decide whether to present sampled antigen in an immunogenic or tolerogenic way.
Romain Pauwels, Karim Vermaelen
openaire   +2 more sources

Dendritic Cells

2009
Dendritic cells (DCs) are sparsely but widely distributed cells of hematopoietic origin that are specialized for the capture, processing and presentation of antigens to T cells. They also play an important role in innate immune function. DCs are heterogeneous and differ in location, migratory pathways and immunologic function.
Pai, Saparna, Thomas, Ranjeny
openaire   +3 more sources

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