Results 141 to 150 of about 58,744 (263)

A data-driven framework for modeling the dendritic spine continuum using dimensionality reduction and clustering toward understanding synaptic plasticity. [PDF]

PLoS One
Sharma US, LeDuc PR, Zhang YJ.
europepmc   +1 more source

Thermal Injury Producing Melanoma‐Like Features on Reflectance Confocal Microscopy

Lasers in Surgery and Medicine, EarlyView.
ABSTRACT Objectives Reflectance confocal microscopy (RCM) improves diagnostic specificity for equivocal pigmented lesions; however, certain conditions may mimic melanoma and limit its accuracy. We aimed to characterize RCM features of thermally injured lesions that mimic melanoma.
Noa Kremer, Isabella N. Dana, Miguel Cordova, Aditi Sahu, Cristian Navarrete‐Dechent, Ashfaq A. Marghoob   +5 more
wiley   +1 more source

Pathogenic human autoantibodies against NMDA receptor alter dendritic spine size. [PDF]

Sci Rep
Matsuda S, Mori T, Kasai M, Kohyama K, Shimada T, Sakuma H.   +5 more
europepmc   +1 more source

Analysis of Carbohydrates and Glycoconjugates by Matrix‐Assisted Laser Desorption/Ionization Mass Spectrometry: An Update for 2023–2024

Mass Spectrometry Reviews, EarlyView.
ABSTRACT The use of MALDI mass spectrometry for the analysis of carbohydrates and glycoconjugates is a well‐established technique and this comprehensive review is the twelfth update of the original article published in 1999 and brings coverage of the literature to the end of 2024.
David J. Harvey
wiley   +1 more source

Regional Specificity of Cortical Layer 3 Dendritic Spine Deficits in Schizophrenia. [PDF]

JAMA Psychiatry
Fish KN, Sweet RA, MacDonald ML, Lewis DA.   +3 more
europepmc   +1 more source

Organoid Coculture Models for Cancer Research and Immunotherapy

Med Research, EarlyView.
This review summarizes organoid coculture platforms, including submerged Matrigel culture, air–liquid interface, microfluidic/organoid‐on‐a‐chip, and 3D bioprinting, for reconstructing the tumor microenvironment to study tumor–stroma/immune crosstalk, evaluate immunotherapies, and enable drug screening.
Zhuo Yang, Huihui Yang, Guangxin Li, Guobang Liu, Zhulan Chen, Wenzhi Tian, Meiyang Huang, Xiaoling Liu, Yongsheng Zhao, Dong Chen   +9 more
wiley   +1 more source

Cerebrolysin Ameliorates Age-Induced Dendritic Spine Degeneration and Memory Decline in C57BL6 Mice. [PDF]

Neurochem Res
Aguilar-Hernández L, Flores-Gómez GD, Nacher J, Morales-Medina JC, Flores G.   +4 more
europepmc   +1 more source

Navigating the Complexity: A Comprehensive Review of GSK‐3 Inhibition in Regenerative Medicine

Medicinal Research Reviews, EarlyView.
ABSTRACT Glycogen synthase kinase‐3 (GSK‐3) is a central regulator of numerous cellular signaling pathways, with critical roles in metabolism, proliferation, differentiation, and tissue regeneration. This review explores the multifaceted effects of pharmacological GSK‐3 inhibition across multiple body districts, focusing on its highly context‐dependent
Davide Schiroli, Alessia Merra, Chiara Marraccini, Lucia Merolle, Graziella Pellegrini, Eleonora Maurizi   +5 more
wiley   +1 more source

AI‐Driven Rational Design of Nanotherapeutics for Pancreatic Ductal Adenocarcinoma

Medicinal Research Reviews, EarlyView.
ABSTRACT Pancreatic ductal adenocarcinoma (PDAC) remains a formidable malignancy characterized by late diagnosis, high recurrence rates, and pronounced chemoresistance. While nanoparticle‐based drug delivery systems (NDDS) offer theoretical advantages over conventional therapies, their clinical translation in PDAC has been severely limited.
Seohyun Choo, Kaeun Chae, Jueun Lee, Inseon Kim, Seunghun S. Lee   +4 more
wiley   +1 more source

A non-canonical ARMS-GABARAP interaction modulates dendritic spine formation and synaptic development. [PDF]

EMBO J
Jiang W, Ye J, Chen J, Wang X, Li Y, Li J, Mei Y, Lyu Y, Hu W, Wang C.   +9 more
europepmc   +1 more source