Results 171 to 180 of about 58,744 (263)

Dendritic spine degeneration is associated with age-related decline in recognition and spatial memory in male mice. [PDF]

Brain Struct Funct
Monroy E, Aguilar-Hernandez L, de la Cruz-López F, Flores G, Morales-Medina JC.   +4 more
europepmc   +1 more source

Large‐Scale Applications of Plasma Technologies: Progresses and Challenges

High Voltage, EarlyView.
ABSTRACT Plasma technologies convert electrical power into energetic electrons, ions, reactive species, radiation and heat, thereby breaking through the bottleneck of purely thermal or chemical routes and bringing impressive changes to our world. This roadmap reviews the progress and challenges of plasma technologies from a large‐scale and application ...
Pankaj Attri, Liuyang Bai, Dmitry Batomunkuev, Xueke Che, Guoxing Chen, Zhitong Chen, Wei Cui, Liguang Dou, Zhi Fang, Yangyang Fu, Fausto Gallucci, Yiming Guo, Bangdou Huang, Yinghong Li, Sirui Li, Hua Liang, Liangliang Lin, Dingxin Liu, Xiangyang Liu, Xinpei Lu, Ruonan Ma, Lanlan Nie, Guanghui Niu, Yuge Ouyang, Tao Shao, Jing Sun, Yong Tang, Xin Tu, Sergey P. Vashchenko, Hang Wang, Xianjie Wang, Anke Weidenkaff, Yun Wu, Haohan Xie, Shaojun Xu, Zongxian Yang, Fangli Yuan, Cheng Zhang, Hao Zhang, Jishen Zhang, Shuai Zhang, Yejian Zhang, Zhe Zhang, Zhibo Zhang, Peng Zhao, Shicheng Zhao, Linlin Zhong, Renwu Zhou, Zhenhua Zhou, Xi Zhu, Yifei Zhu, Haohua Zong   +51 more
wiley   +1 more source

Assessing a Model for a Complex Systemic Disorder—The Value of Male Mice With a Supernumerary X Chromosome for Klinefelter Syndrome Research

Andrology, EarlyView.
ABSTRACT Introduction Direct experimental investigation of Klinefelter syndrome (KS) in patients is limited because the syndrome manifests heterogeneously and affects multiple organ systems. Studying KS therefore requires a model that captures this complexity as accurately as possible while still permitting controlled experimental manipulation ...
Fariba Saadati, Joachim Wistuba
wiley   +1 more source

Distinctly altered TRPC3 and TRPC6 expression patterns in human Alzheimer's disease cortex and hippocampus

Brain Pathology, EarlyView.
Divergent remodeling of TRPC channels occurs in Alzheimer's disease, with TRPC3 increased in neurons and reactive astrocytes and TRPC6 reduced in pyramidal neurons. These alterations may contribute to calcium dysregulation, neuroinflammation, and synaptic dysfunction during AD progression.
Xingyong Chen, Zhengjun Wang, Jiaxing Wang, Dehui Kong, Xusheng Wang, Lu Lu, Peter T. Nelson, Fu‐Ming Zhou, Francesca‐Fang Liao   +8 more
wiley   +1 more source

Principles for Dendritic Spine Size and Density in Human and Mouse Cortical Pyramidal Neurons. [PDF]

J Comp Neurol
Benavides-Piccione R, Fernaud-Espinosa I, Kastanauskaite A, DeFelipe J.   +3 more
europepmc   +1 more source

Non‐Alzheimer Aβ deposits in the human CNS: Implications with hypoxia and related conditions

Brain Pathology, EarlyView.
An Aβ deposit in a non‐Alzheimer's brain from an individual who experienced hypoxia/energy failure. Abstract We recently reported the deposition of Aβ in the frontal cortex of individuals who died of acute coronavirus disease 2019 (COVID‐19), or who did not have COVID‐19 but had respiratory distress, or infants with severe cardiac malformations.
Esma Karlovich, David S. Priemer, Charles Harker Rhodes, Daniel P. Perl, Kurenai Tanji, James E. Goldman   +5 more
wiley   +1 more source

Peripheral targets for neuropathic pain

British Journal of Pharmacology, EarlyView.
Neuropathic pain represents a significant clinical challenge, with still limited pharmacological approaches to symptomatic relief. This review focuses on molecular targets implicated in neuropathic pain, particularly those involved in peripheral mechanisms. Using the IUPHAR/BPS database of biological targets, their occurrence together with ‘neuropathic
Amirhossein Afsharipour, Cosmin I. Ciotu, Felix J. Resch, Michael J. M. Fischer   +3 more
wiley   +1 more source

The MCPH7 Gene Product STIL Is Essential for Dendritic Spine Formation. [PDF]

Cells
Matsuki T, Tabata H, Ueda M, Ito H, Nagata KI, Tsuneura Y, Eda S, Kasai K, Nakayama A.   +8 more
europepmc   +1 more source

CD93—An emerging vascular target in cancer therapy

British Journal of Pharmacology, EarlyView.
Abstract CD93 is a single‐pass transmembrane glycoprotein that belongs to the C‐type lectin domain group XIV family of proteins. Although it is known to be expressed in other cell types, namely, in some subsets of immune cells, CD93 is primarily expressed on endothelial cells, where it acts as a crucial regulator of angiogenesis.
Beatriz de Alves Pereira, Stefano Barbera, Roberta Lugano, Anna Dimberg   +3 more
wiley   +1 more source

Gestational hypothyroxinemia causes an inflammatory environment at maternal-fetal tissues and fetal brain with impaired hippocampal dendritic spine maturation in the offspring. [PDF]

Sci Rep
González-Madrid E, Rangel-Ramírez MA, Opazo MC, Espinoza SA, Elgueta D, Cancino GI, Mery E, Ardiles ÁO, Duarte LF, Soto JA, Carreño LJ, Simon F, Bueno SM, González PA, Kalergis AM, Riedel CA.   +15 more
europepmc   +1 more source