Results 41 to 50 of about 924,020 (209)

Orally administered boldine reduces muscle atrophy and promotes neuromuscular recovery in a rodent model of delayed nerve repair

open access: yesFrontiers in Cellular Neuroscience, 2023
Peripheral nerve injury often results in poor functional recovery due to a prolonged period of muscle denervation. In particular, absent axonal contact, denervated muscle can undergo irrevocable atrophy and diminished receptiveness for reinnervation over
Justin C. Burrell   +12 more
doaj   +1 more source

Denervation in hemiplegic muscles. [PDF]

open access: yesStroke, 1990
This study examined the frequency of denervation activity in hemiplegic muscles in relation to the size and location of the central lesion. We studied 20 patients, 14 with major unilateral cerebral infarctions in the middle cerebral or internal carotid territories; four with a single lacune in the pons, internal capsule, or thalamus; and two with ...
W F, Brown, R, Snow
openaire   +2 more sources

Targeted Muscle Reinnervation for Intuitive Prosthetic Control

open access: yesMuscle &Nerve, EarlyView.
ABSTRACT The convergence of medical and technological advances has led to a substantial expansion of therapeutic approaches for patients with limb amputations. Targeted muscle reinnervation (TMR) is one of the strategies to improve control of bionic arms and has been applied for more than two decades. Through surgical rewiring of the nerves responsible
Nitay Maile   +5 more
wiley   +1 more source

Quantitative Ultrasound Analysis of Muscle Reinnervation Following Anterior Interosseous Nerve‐To‐Ulnar Motor Branch Supercharged End‐To‐Side Transfer Surgery: A Preliminary Study

open access: yesMuscle &Nerve, EarlyView.
ABSTRACT Introduction/Aims Routine assessment of muscle reinnervation primarily relies on clinical and electromyographic evaluation. The aim of this preliminary study was to evaluate sensitivity of quantitative ultrasound analysis for monitoring intrinsic hand muscle recovery following anterior interosseous nerve (AIN)‐to‐ulnar motor branch ...
Rémy Liechti, Esther Vögelin
wiley   +1 more source

18 F-ASEM PET/MRI targeting alpha7-nicotinic acetylcholine receptor can reveal skeletal muscle denervation

open access: yesEJNMMI Research
Background The increased expression of the nicotinic acetylcholine receptor (nAChR) in muscle denervation is thought to be associated with electrophysiological acetylcholine supersensitivity after nerve injury.
Yong-il Kim   +10 more
doaj   +1 more source

Absence of physiological Ca2+ transients is an initial trigger for mitochondrial dysfunction in skeletal muscle following denervation

open access: yesSkeletal Muscle, 2017
Background Motor neurons control muscle contraction by initiating action potentials in muscle. Denervation of muscle from motor neurons leads to muscle atrophy, which is linked to mitochondrial dysfunction.
Chehade Karam   +11 more
doaj   +1 more source

Regenerative Injection Laryngoplasty With Scaffold‐Forming Oligomer and Autologous Motor Endplate‐Expressing Cells: A 6‐Month Porcine Study

open access: yesOtolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective Injection laryngoplasty is a standard‐of‐care intervention for unilateral vocal fold paralysis (UVFP), offering minimally invasive medialization with limited durability. We evaluated a regenerative injectable approach integrating an immunotolerant scaffold‐forming collagen (Oligomer) with autologous motor‐endplate expressing (MEE ...
Gabriel G. Sobczak   +9 more
wiley   +1 more source

Dynamic properties of denervated rat muscle treated with electrotherapy

open access: yes, 1963
Denervated rat gastrocnemii, compared with normal controls, showed slower shortening velocity and less shortening, performed less work, exhibited decreased values for Hill's constant a (shortening heat per centimeter shortening), a low P0 (maximum ...
D. R. Elliott, J. D. Thomson
core   +1 more source

Excitation-contraction coupling and mechano-sensitivity in denervated skeletal muscles

open access: yesEuropean Journal of Translational Myology, 2010
Skeletal muscle atrophy can be defined as a wasting or decrease in muscle mass and muscle force generation owing lack of use, ageing, injury or disease. Thus, the etiology of atrophy can be different.
Fabio Francini, Roberta Squecco
doaj   +1 more source

The predictive nature of diagnostic nerve blocks for lower extremity spasticity management with botulinum toxin and neurotomy: A systematic review

open access: yesPM&R, EarlyView.
Abstract Introduction/Objective Diagnostic nerve blocks (DNBs) involve the injection of anesthetic around peripheral nerves to temporarily reduce motor tone. Although they are used clinically to inform spasticity treatment with neurotomy and chemodenervation, there is little research exploring the predictive nature of DNBs.
Katherine Archibold   +3 more
wiley   +1 more source

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