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Dengue and Dengue Hemorrhagic Fever [PDF]

Clinical Microbiology Reviews, 1997
SUMMARYDengue fever, a very old disease, has reemerged in the past 20 years with an expanded geographic distribution of both the viruses and the mosquito vectors, increased epidemic activity, the development of hyperendemicity (the cocirculation of multiple serotypes), and the emergence of dengue hemorrhagic fever in new geographic regions.
E B, Hayes, D J, Gubler
openaire   +5 more sources

Development of a Singleplex Real-Time Reverse Transcriptase PCR Assay for Pan-Dengue Virus Detection and Quantification

Viruses, 2022
Dengue virus (DENV) infection is a significant global health problem. There are no specific therapeutics or widely available vaccines. Early diagnosis is critical for patient management.
Adisak Songjaeng, Somchai Thiemmeca, Dumrong Mairiang, Nuntaya Punyadee, Kessiri Kongmanas, Prachya Hansuealueang, Nattaya Tangthawornchaikul, Thaneeya Duangchinda, Juthathip Mongkolsapaya, Kanokwan Sriruksa, Wannee Limpitikul, Prida Malasit, Panisadee Avirutnan   +12 more
doaj   +1 more source

Dengue virus NS1 secretion is regulated via importin-subunit β1 controlling expression of the chaperone GRp78 and targeted by the clinical drug ivermectin

mBio, 2023
Dengue virus (DENV) is a major human pathogen. An important pathogenicity factor is non-structural protein 1 (NS1) required for viral replication and secreted from infected cells.
Solène Denolly, Hongbo Guo, Miriam Martens, Anna Płaszczyca, Pietro Scaturro, Vibhu Prasad, Kessiri Kongmanas, Nuntaya Punyadee, Adisak Songjaeng, Dumrong Mairiang, Andreas Pichlmair, Panisadee Avirutnan, Ralf Bartenschlager   +12 more
doaj   +1 more source

Synergistic anti-SARS-CoV-2 activity of repurposed anti-parasitic drug combinations

BMC Pharmacology and Toxicology, 2022
Background COVID-19 pandemic has claimed millions of lives and devastated the health service system, livelihood, and economy in many countries worldwide.
Kunlakanya Jitobaom, Chompunuch Boonarkart, Suwimon Manopwisedjaroen, Nuntaya Punyadee, Suparerk Borwornpinyo, Arunee Thitithanyanont, Panisadee Avirutnan, Prasert Auewarakul   +7 more
doaj   +1 more source

Genetic Variation in the Domain II, 3′ Untranslated Region of Human and Mosquito Derived Dengue Virus Strains in Sri Lanka

Viruses, 2021
Genetic variations in dengue virus (DENV) play a distinct role in epidemic emergence. The DENV 3′ UTR has become a recent interest in research. The objective of the study was to examine the genetic variation in the domain II, 3′ UTR region of human and ...
P. D. Dayananda, Harendra de Silva, LakKumar Fernando, B. G. D. N. K. de Silva   +3 more
doaj   +1 more source

Facial nerve palsy: An atypical presentation of dengue fever

Asian Journal of Medical Sciences, 2023
Dengue fever is a grave public health concern in tropical countries. The disease spectrum of dengue fever is multi-systemic, although neurologic complications of dengue fever is relatively uncommon. The pathogenesis of neurologic manifestations in dengue
Rishav Mukherjee , Debarup Das
doaj   +1 more source

Predictive value of persistent NS1 antigen positivity beyond 3rd day for dengue haemorrhagic fever in Sri Lankan children

BMC Research Notes, 2019
Objective Dengue haemorrhagic fever (DHF) is a major public health concern responsible for significant morbidity in both adult and paediatric populations in Sri Lanka.
Mihira Manamperi, Bernard Deepal Wanniarachchi Jayamanne, Thilini Somaratne, Natasha Perera, LakKumar Fernando   +4 more
doaj   +1 more source

Frequency of Capillary leak syndrome in Dengue fever Patients

Journal of Rawalpindi Medical College, 2021
Background: Dengue fever is the world’s fastest spreading mosquito borne viral infection. It is prevalent throughout both subtropical and tropical region if the world.
Safina Hameed Qureshi, Sania Hameed Qureshi, Syed Fahd Shah, Farid Ullah Shah, Syed Zubair Shah, Syed Hussain Shah   +5 more
doaj   +1 more source

Unmasking the role of mast cells in dengue

eLife, 2013
Immune cells called mast cells can hinder rather than help the body's response to dengue virus, which suggests that mast cell products could be used as biomarkers to identify severe forms of the disease.
Panisadee Avirutnan, Ponpan Matangkasombut   +1 more
doaj   +1 more source

Ultrastructural Features of Human Liver Specimens from Patients Who Died of Dengue Hemorrhagic Fever

Tropical Medicine and Infectious Disease, 2019
Recent advances in electron microscopy and tomography have revealed distinct virus-induced endoplasmic reticulum (ER) structures unique for dengue virus (DV) and other flaviviruses in cell culture models, including hepatocytes.
Min Min Win, Komgrid Charngkaew, Nuntaya Punyadee, Khin Saw Aye, Ne Win, Urai Chaisri, Nusara Chomanee, Panisadee Avirutnan, Sutee Yoksan, Prida Malasit   +9 more
doaj   +1 more source