An In-Silico Investigation of Phytochemicals as Antiviral Agents Against Dengue Fever
: A virtual screening analysis of our library of phytochemical structures with dengue virus protein targets has been carried out using a molecular docking approach. A total of 2194 plant-derived secondary metabolites have been docked.
Chelsea N. Powers, W. Setzer
semanticscholar +1 more source
The Difference of C-Reactive Protein Levels in Acute Fever caused by Dengue and Typhoid Infections
Introduction. Dengue infection and typhoid fever are endemic disease in Indonesia. But in the early days of onset sometimes it is difficult to distinguish them. A simple modality test is needed to support the diagnosis.
Adeputri Tanesha Idhayu+3 more
doaj +1 more source
Dengue Hemorrhagic Fever: A State-of-the-Art Review Focused in Pulmonary Involvement
Dengue fever is an arboviral disease transmitted to humans through the bites of infected female Aedes mosquitoes. Dengue virus is a member of the Flaviviridae family, and human infection can be caused by any of the four antigenically distinct serotypes ...
Renata Rocha de Almeida+7 more
semanticscholar +1 more source
CLEC18A is a previously poorly characterized C‐type lectin. We mapped the expression of CLEC18A to the proximal tubule of the kidney and found CLEC18A to interact with sulfated glycosaminoglycans on proteoglycans. Furthermore, we found that CLEC18A plays an important role in hindering the progression of clear cell renal cell carcinomas in humans and in
Gustav Jonsson+10 more
wiley +1 more source
Unusual Presentation of Dengue Fever Leading to Unnecessary Appendectomy
Dengue fever is the most important arbovirus illness with an estimated incidence of 50–100 million cases per year. The common symptoms of dengue include fever, rash, malaise, nausea, vomiting, and musculoskeletal pain.
Lovekesh Kumar+7 more
doaj +1 more source
Infections Caused by Carbapenem-Resistant Enterobacteriaceae: An Update on Therapeutic Options
Carbapenems are considered as last-resort antibiotics for the treatment of infections caused by multidrug-resistant Gram-negative bacteria. With the increasing use of carbapenems in clinical practice, the emergence of carbapenem-resistant pathogens now ...
Chau-Chyun Sheu+10 more
doaj +1 more source
Progress towards understanding the pathogenesis of dengue hemorrhagic fever
Dengue virus (DENV) is a mosquito-borne virus belonging to the Flaviviridae family. There are 4 serotypes of DENV that cause human disease through transmission by mosquito vectors.
X. Pang, Rudian Zhang, G. Cheng
semanticscholar +1 more source
The possibly neglected victims: Re‐examining the involvement of children in the chikungunya epidemic
Pediatric Investigation, EarlyView.
Ran Wang, Kevin C. Kain, Zhengde Xie
wiley +1 more source
Flagellins as Vaccine Adjuvants and Cancer Immunotherapy: Recent Advances and Future Prospects
The figure depicts the role of flagellin in immune cells. Flagellin interacts with TLR5, resulting in the formation of homodimers and the recruitment of MyD88, which activates the IκB and MAPK signalling pathways. This results in the activation of NF‐κB and AP‐1, producing TNF‐α, IL‐6, IL‐8, and IL‐12.
Asma Talukder+4 more
wiley +1 more source
Should We Advance Our Understanding of Immunoglobulin E in Viral Immunity?
Immunoglobulin E has been extensively studied in allergies and parasitic diseases. Antigen‐specific IgE has been identified as part of the humoral response to viruses. This revision speculates on possible functionalities for IgE, such as neutralisation, cytotoxicity and immunopathology of viral diseases, and provide insights about gaps to fill in ...
Amanda Izeli Portilho+3 more
wiley +1 more source