Results 61 to 70 of about 82,510 (260)

The Role of Cytokines in Activation of Coagulation and Fibrinolysis in Dengue Shock Syndrome [PDF]

, 2002
In a prospective clinical study of 50 patients with Dengue Shock Syndrome (DSS), we investigated the association of tumor necrosis factor- (TNF-), interleukin-1 (IL-1), IL-1 receptor antagonist (IL-1Ra), and IL-6 with activation markers of coagulation
Dolmans, Wil M.V., van der Meer, Jos W. M., Wil Dolmans, Setiati, T.E., Dolmans, W.M.V., C. Hack, Jos van der Meer, Hugo ten Cate, Hack, C. Erik, Hack, C.E., Djokomoeljanto, R.J., Cate, H. ten, Djokomoeljanto, Robert J., Cate, Hugo ten, Suharti, C., Catharina Suharti, Djokomoeljanto, Robert J., Gorp, E. van, Meer, J.W.M. van der, Dolmans, Wil M. V., Setiati, Tatty E., Meer, Jos W.M. van der, Eric van Gorp, Napel, C.H.H. ten, Gorp , Eric C.M. van, ten, Cate Hugo, Suharti, Catharina, Setiati , Tatty E., Robert Djokomoeljanto, Gorp, E.C.M. van, van Gorp, Eric C. M., Tatty Setiati   +31 more
core   +1 more source

Domperidone inhibits dengue virus infection by targeting the viral envelope protein and nonstructural protein 1

Scientific Reports
Dengue is a mosquito-borne disease caused by dengue virus (DENV) infection, which remains a major public health concern worldwide owing to the lack of specific treatments or antiviral drugs available.
Nuttapong Kaewjiw, Thanawat Thaingtamtanha, Damini Mehra, Wanida Chawnawa, Tanapan Prommool, Chunya Puttikhunt, Adisak Songjaeng, Kessiri Kongmanas, Panisadee Avirutnan, Prasit Luangaram, Chatchawan Srisawat, Sittiruk Roytrakul, Stephan A. Bäurle, Sansanee Noisakran   +13 more
doaj   +1 more source

N‐acetylcysteine for non‐paracetamol‐induced acute liver failure in children: A systematic review and meta‐analysis

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Non‐surgical treatment of acute liver failure (ALF) is primarily supportive and depends on the underlying cause. While N‐acetylcysteine (NAC) is proven effective in paracetamol‐induced ALF, its potential benefits in non‐paracetamol ALF for paediatric patients remain unclear.
Alise D. E. de Groot, Désanka M. Stoppels, Arno R. Bourgonje, Willemien F. J. Hof, Martin C. J. Kneyber, Daan J. Touw, Henkjan J. Verkade, Paola Mian   +7 more
wiley   +1 more source

Role of the chemokine receptors CCR1, CCR2 and CCR4 in the pathogenesis of experimental dengue infection in mice [PDF]

, 2010
Dengue virus (DENV), a mosquito-borne flavivirus, is a public health problem in many tropical countries. Recent clinical data have shown an association between levels of different chemokines in plasma and severity of dengue.
Mauro M Teixeira, Besnard, Anne-Gaëlle, Danielle G Souza, Fagundes, C.T., Teixeira, Mauro M, Guabiraba Rodrigo, Fagundes Caio T., Teixeira Mauro M., Anne-Gaëlle Besnard, Souza, Danielle G., Souza Danielle G., Danielle G. Souza, Mauro M. Teixeira, Teixeira, M.M., Caio T Fagundes, Ryffel Bernhard, Bernhard Ryffel, Souza, Danielle G, Besnard, A., Marques, Rafael Elias, Fagundes, Caio T., Ryffel, Bernhard, Rodrigo Guabiraba, Fagundes, Caio T, Marques Rafael Elias, Marques, R.E., Guabiraba, Rodrigo, Guabiraba Brito, R., Besnard Anne-Gaëlle, Rafael Elias Marques, Caio T. Fagundes   +30 more
core   +1 more source

Single‐Cell Profiling Identifies CLEC5A+ Macrophages as Key Drivers of Thoracic Aortic Aneurysm Via CCL5‐Mediated M1 Polarization

Journal of Clinical Laboratory Analysis, EarlyView.
Thoracic aortic aneurysm (TAA) is a life‐threatening cardiovascular disease with limited therapeutic options. Through single‐cell RNA sequencing of aortic tissues from healthy individuals and TAA patients (105,541 cells), we identified CLEC5A+macrophages as the predominant pathogenic cell population exhibiting the highest M1 polarization score. Machine
Xiangyu Li, Chunguang Guo, Mingyao Luo, Chang Shu   +3 more
wiley   +1 more source

Fever in a traveler returning from the Amazon. Do not forget hepatitis A

IDCases, 2016
Travelers returning from the tropics with fever remain a diagnostic challenge. Fever and chills suggest malaria, but may be present in dengue, chikungunya and influenza, and splenomegaly favors malaria or typhoid fever.
Burke A. Cunha, Rina Seerke Teper, Muhammad Raza   +2 more
doaj   +1 more source

Analysis of Gene Expression in Aedes aegypti Suggests Changes in Early Genetic Control of Mosquito Development

Journal of Experimental Zoology Part B: Molecular and Developmental Evolution, EarlyView.
ABSTRACT Aedes aegypti, a critical vector for tropical diseases, poses significant challenges for studying its embryogenesis due to difficulties in removing its rigid chorion and achieving effective fixation for in situ hybridization. Here, we present novel methodologies for fixation, dechorionation, DAPI staining, and in situ hybridization, enabling ...
Renata Coutinho‐dos‐Santos, Danielle Santos, Lupis Ribeiro, Jonathan J. Mucherino‐Muñoz, Marcelle Uhl, Carlos Logullo, A. Mendonça‐Amarante, M. Fantappie, Rodrigo Nunes‐da‐Fonseca   +8 more
wiley   +1 more source

Validity and Usefulness of Revised WHO Guidelines in Children with Dengue Fever [PDF]

Journal of Clinical and Diagnostic Research, 2018
Introduction: Dengue fever is the most rapidly spreading mosquito borne viral infection with a 30-fold increase in the disease burden over last five decades with a variable clinical course and outcome.
Sriram Pothapregada, Vijayalakshmi Sivapurapu, Banupriya Kamalakannan, Mahalakshmy Thulasingham   +3 more
doaj   +1 more source

Economic burden of dengue fever in China: A retrospective research study.

PLoS Neglected Tropical Diseases, 2022
BackgroundDengue fever has been a significant public health challenge in China. This will be particularly important in the context of global warming, frequent international travels, and urbanization with increasing city size and population movement.
Meng Xu, Nan Chang, Taotian Tu, Jimin Sun, Jinyong Jiang, Yu Xia, Wenge Tang, Hengqing Ji, Xiaotao Zhao, Jin Zhu, Li Qi, Xiaobo Liu, Qiyong Liu   +12 more
doaj   +1 more source

17‐epi‐Melianodiol, a new protolimonoid from Melia azedarach fruits, exhibits larvicidal activity and is associated with oxidative imbalance and midgut epithelial damage in Aedes aegypti larvae

Pest Management Science, EarlyView.
The bio‐guided phytochemical study resulted in the new compound 17‐epi‐melianodiol. The compound eliminated 100% of Aedes aegypti larvae at 100 ppm, causing pronounced morphological changes, cuticular damage, and extensive vacuolization. Abstract BACKGROUND In Brazil, Aedes aegypti is the primary vector of arboviruses such as dengue, chikungunya ...
Kethleen Duarte Crespo Soares, Thalya Soares Ribeiro Nogueira, Maria Aparecida Aride Bertonceli, Renata Rodrigues da Silva Robaina, Leticia Oliveira da Rocha, Francisco José Alves Lemos, Kátia Valevski Sales Fernandes, Raimundo Braz‐Filho, Ivo José Curcino Vieira   +8 more
wiley   +1 more source