Results 91 to 100 of about 1,391,312 (259)

Evaluation of the performance of a dengue outbreak detection tool for China [PDF]

open access: yes, 2014
An outbreak detection and response system, using time series moving percentile method based on historical data, in China has been used for identifying dengue fever outbreaks since 2008.
Wang, Liping   +31 more
core   +1 more source

Contribution of endosomal proteins EHD1 and EHD4 to the HIV‐1 replication cycle

open access: yesThe FEBS Journal, EarlyView.
EHD1 and EHD4, two key trafficking proteins, regulate multiple stages of HIV‐1 infection: In producer cells, they help produce fully infectious virus particles, regulate Envelope protein incorporation in a cell‐type‐dependent manner, and limit the accumulation of antiviral IFITM proteins in virions.
Grégory Pacini   +4 more
wiley   +1 more source

Conserved dimerization architecture in C‐type lectins from virus‐vector mosquitoes

open access: yesThe FEBS Journal, EarlyView.
C‐type lectins (CTLs) are involved in the detection of viral/microbial carbohydrates. We studied a family of soluble CTLs in the mosquito Aedes aegypti, which acts as a vector for viruses like dengue and Zika. Using crystallography, biophysics, and structure prediction approaches, we found that these proteins consistently pair together in the same ...
Mattia Bertinelli   +6 more
wiley   +1 more source

Prophylactic platelets in dengue: survey responses highlight lack of an evidence base. [PDF]

open access: yes, 2012
Dengue is the most important arboviral infection of humans. Thrombocytopenia is frequently observed in the course of infection and haemorrhage may occur in severe disease.
Guzman Maria G.   +164 more
core   +2 more sources

Structures of the UBR4 complex reveal a giant arena to capture diverse substrates for ubiquitin chain elongation

open access: yesThe FEBS Journal, EarlyView.
This review summarizes recent structures of the UBR4 complex, a giant E4 ubiquitin ligase which recognizes proteins with pre‐existing ubiquitin modifications and marks them for degradation. The UBR4 complex uses a large arena lined with substrate interaction modules to select features on ubiquitinated substrates, such as the presence of N‐degrons or ...
Daniel B. Grabarczyk, Tim Clausen
wiley   +1 more source

Casos de malaltia per Virus Chikungunya, Dengue i Zika a Catalunya: informe 2018 [PDF]

open access: yes, 2019
Virus Chikungunya; Dengue; ZinkaChikungunya virus; Dengue; ZinkaVirus Chikungunya; Dengue; ZinkaDocument que ofereix el resum dels casos de malaltia per Virus Chikungunya, Dengue i Zika a Catalunya durant un període de l'any ...
Garcia-Prado, Maria S.   +1 more
core  

Roles for Endothelial Cells in Dengue Virus Infection

open access: yesAdvances in Virology, 2012
Dengue viruses cause two severe diseases that alter vascular fluid barrier functions, dengue hemorrhagic fever (DHF) and dengue shock syndrome (DSS). The endothelium is the primary fluid barrier of the vasculature and ultimately the effects of dengue ...
Nadine A. Dalrymple, Erich R. Mackow
doaj   +1 more source

Virus Dengue: Dasar Molekuler, Mekanisme Masuknya ke dalam Sel Target serta Imunopathogenesis yang Ditimbulkannya

open access: yesJurnal Vektor Penyakit, 2017
Dengue hemorrhagic fever is still one of the major public health problem worldwide, particularly in sub tropical and tropical regions. The disease is caused by the presence of dengue virus infection (DENVa), member of the Flaviviridae family.
Triwibowo Ambar Garjito
doaj   +1 more source

STUDIES ON DENGUE VIRUS (XI)

open access: yesVIRUS, 1957
Electron micrographs of dengue viruses of Hawaiian strain and Mochizuki strain, which were adapted to mouse brain and chick embryo have been taken using purified virus materials.Purification methods employed were as follows: (I) Combination of partial purification of the virus adsorption to and elution from erythrocytes and ultracentrifuge, (2 ...
YOH NAKAGAWA, MASAHISA SHINGU
openaire   +3 more sources

A comparative analysis of cell death signalling in RNA and DNA virus infections and potential inhibitory strategies

open access: yesThe FEBS Journal, EarlyView.
RNA and DNA viruses can manipulate host cell death through various mechanisms. RNA viruses (H1N1, SARS‐CoV‐2) induce acute apoptosis, necroptosis, and pyroptosis to promote rapid viral transmission and epithelial barrier damage. In contrast, DNA viruses (HSV‐1, EBV) regulate these mechanisms to sustain a lytic‐latency cycle, evade immune response and ...
Panagiotis Keramidas   +4 more
wiley   +1 more source

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